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Results for "

IMP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (1) Antibiotic (2) Apoptosis (1) ATP Synthase (2) Autophagy (1) Bacterial (20) Bcl-2 Family (1) Beta-lactamase (19) Biochemical Assay Reagents (3) CDK (2) Cytochrome P450 (1) Dengue Virus (1) Deubiquitinase (2) DNA/RNA Synthesis (6) Dopamine Transporter (2) Drug Intermediate (3) Drug Isomer (1) Drug Metabolite (3) EGFR (1) Endogenous Metabolite (8) Environmental Pollutants (1) Flavivirus (1) Hapten (1) Hedgehog (1) HIV (1) HSV (1) IGF-1R (1) IMPDH (1) Insulin Receptor (4) Isotope-Labeled Compounds (4) LAG-3 (2) Microtubule/Tubulin (1) Mitophagy (1) Monoamine Transporter (1) N-myristoyltransferase (2) Nucleoside Antimetabolite/Analog (2) Orthopoxvirus (1) Parasite (4) PARP (2) Reference Standards (4) SARS-CoV (1) Serotonin Transporter (1) Small Interfering RNA (siRNA) (9) STING (2)
By Research Areas:	Cancer (23) Infection (32) Metabolic Disease (3) Neurological Disease (2)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (4) siRNAs (9)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15310

Ivermectin Maximum Cited Publications 48 Publications Verification MK-933; CD-5024; K-237	Environmental Pollutants Antibiotic Mitophagy Bacterial Parasite Autophagy Flavivirus HSV HIV SARS-CoV Dengue Virus	Infection Cancer
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

HY-108213

Inosinic acid 4 Publications Verification 5'-IMP; IMP; Inosine 5'-dihydrogen phosphate	Endogenous Metabolite	Others
Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-112258

IMP-1088 5+ Cited Publications	DNA/RNA Synthesis	Infection
IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC₅₀s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a K_d of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection .

HY-137450

Senaparib IMP4297; JS109	PARP	Cancer
Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models .

HY-103056

DDD85646 1 Publications Verification IMP-366	DNA/RNA Synthesis Parasite	Infection
DDD85646 (IMP-366) is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC₅₀=2 nM; hNMT IC₅₀=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis .

HY-164285

MYX1715 IMP1320	ADC Payload N-myristoyltransferase	Cancer
MYX1715 is an inhibitor of N-Myristoyltransferase (NMT) with a K_D value of 0.09 nM. MYX1715 inhibits the proliferation of LU0884 and LU2511 with IC₅₀ values of 44 nM and 9 nM. MYX1715 exhibits antitumor efficacy against neuroblastoma and gastric cancer in mouse models. MYX1715 can be used as ADC toxin .

HY-148493

MK-3402	Bacterial	Infection
MK-3402 (Compound303) is a metallo-beta-lactamase inhibitor, with IC₅₀ values of 0.53, 0.25 and 0.169 nM against *IMP-1, NDM-1, and VIM-1*, respectively. MK-3402 can be used in bacterial research and shows a synergistic effect when used in combination with beta-lactam antibiotics .

HY-16933

L-Alanosine 1 Publications Verification NSC-153353; SDX-102	Antibiotic DNA/RNA Synthesis	Infection Cancer
L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine is the inhibitor for methylthioadenosine phosphorylase (MTAP) .

HY-D0887

Disodium 5'-inosinate 1 Publications Verification IMP disodium salt; Disodium inosinate	Others	Metabolic Disease
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .

HY-135396

(1S,2S)-Bortezomib	Drug Isomer	Others
(1S,2S)-Bortezomib (Compound Imp-D (1S,2S)) is a diastereomeric impurity of Bortezomib (HY-10227) .

HY-138995

IMP-1710 1 Publications Verification	Deubiquitinase	Others
IMP-1710 is a potent and selective deubiquitylating enzyme UCHL1 inhibitor with an IC₅₀ value of 38 nM. IMP-1710 has antifibrotic activity. IMP-1710 is a UCHL1 probe to identify and quantify target proteins in intact human cells . IMP-1710 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IMP-1710 can be used in the research of idiopathic pulmonary fibrosis .

HY-114570

Tiazofurin 1 Publications Verification NSC 286193; Riboxamide	Nucleoside Antimetabolite/Analog Orthopoxvirus	Infection Neurological Disease Cancer
Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH). Tiazofurin enhances the autosecretion of IL-6 in K562 cells. Tiazofurin also has anti-orthopoxvirus and anti-variola activities. Tiazofurin can be used for the study of leukemia and lung cancer .

HY-146178

IMP2-IN-1	Insulin Receptor	Cancer
IMP2-IN-1 (compound 4) is a potent *IMP2* inhibitor with IC₅₀ value of 81.3~127.5 for IMP2 RNA sequence. IMP2-IN-1 reduces IMP2 in SW480 cells. IMP2-IN-1 significantly reduces the viability of both differentiated and non-differentiated Huh7 cells .

HY-133157

FAICAR 5-Formamidoimidazole-4-carboxamide ribotide	DNA/RNA Synthesis	Infection
FAICAR (5-Formamidoimidazole-4-carboxamide ribotide) is a purine nucleotide and the IMP cyclohydrolase substrate of Cryptococcus neoformans ATIC. It is a key intermediate in the de novo purine synthesis pathway. FAICAR can be used in studies related to Cryptococcus neoformans infection .

HY-108213R

Inosinic acid (Standard) 5'-IMP (Standard); IMP (Standard); Inosine 5'-dihydrogen phosphate (Standard)	Reference Standards Endogenous Metabolite	Others
Inosinic acid (Standard) is the analytical standard of Inosinic acid. This product is intended for research and analytical applications. Inosinic acid is an endogenous metabolite. Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-D2188

IMP-2373	Deubiquitinase	Cancer
IMP-2373 is a low-toxicity activity-based probe targeting covalent pan-deubiquitinase (DUB), which modulates and monitors DUB activity via covalent binding to the catalytic cysteine and active site of DUB. IMP-2373 enables real-time tracking of dynamic intracellular DUB activity in physiologically relevant living cell systems, and quantitative analysis of activity changes induced by pharmacological inhibition or MYC dysregulation. IMP-2373 can be used for research on related diseases such as B-cell lymphoma .

HY-P991301

IMP-761	LAG-3	Cancer
IMP-761 is a human IgG4 monoclonal antibody (mAb) targeting CD223/LAG3. IMP-761 binds to D1 of human LAG32. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003) .

HY-146179

IMP2-IN-2	Insulin Receptor	Cancer
IMP2-IN-2 (compound 6) is a potent and selective *IMP2* inhibitor, with IC₅₀s of 120.9 μM and 236.7 μM for IMP2 interaction with RNA_A and RNA_B, respectively. IMP2-IN-2 can be used for the research of cancer .

HY-129972

Ribavirin 5'-monophosphate dilithium RMP dilithium	Nucleoside Antimetabolite/Analog	Others
Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent .

HY-P99027

Ieramilimab LAG525; IMP701; Hu5A8	LAG-3	Cancer
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules. Ieramilimab restores T-cell and NK-cell-mediated antileukemic immunity by reducing exhaustion and augmenting cytokine output and cytotoxicity. Ieramilimab increases the infiltration of cytotoxic T lymphocytes and reduces baseline densities of regulatory T cells (Tregs) and ADAM10-expressing tumor cells. Ieramilimab can be used for the study of various malignancies including melanoma, RCC, and advanced solid tumors .

HY-136498A

T-705RMP ammonium	Drug Metabolite	Infection
T-705RMP (ammonium) is the ammonium form of T-705RMP. T-705RMP (ammonium)’s the inhibition of IMP dehydrogenase (IMPDH) activity is weak .

HY-W717548

Safinamide acid	Drug Metabolite	Others
Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples .

HY-161712

IMPDH-IN-4	IMPDH	Cancer
IMPDH-IN-4 is a derivative of N-pyridinylthiophene carboxamid that exhibits activity against peripheral nerve sheath carcinoma cells. IMPDH-IN-4 is metabolized by NAMPT and NMNAT1 to an adenine dinucleotide (AD) derivative, which is an NAD analog and can inhibit inosine monophosphate dehydrogenase (IMPDH), leading to the accumulation of inosine monophosphate (IMP) in cells. IMPDH-IN-4 has good blood-brain barrier permeability and can be used in the study of central and peripheral nervous system cancers .

HY-161175

IMP-1575	Hedgehog	Cancer
IMP-1575 is the most potent Hedgehog acyltransferase (HHAT) inhibitor, with an IC₅₀ of 0.75 μM for inhibition of purified HHAT. IMP-1575 can be used for the research of cancer .

HY-108213A

Inosinic acid disodiumhydrate(1:2:X) 4 Publications Verification 5'-IMP disodiumhydrate(1:2:X); IMP disodiumhydrate(1:2:X); Inosine 5'-dihydrogen phosphate disodiumhydrate(1:2:X)	Endogenous Metabolite	Others
Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-W703376

2-(tert-Butylamino)-1-phenylpropan-1-one hydrochloride	Serotonin Transporter Monoamine Transporter Dopamine Transporter	Neurological Disease
2-(tert-Butylamino)-1-phenylpropan-1-one hydrochloride (Compound Imp.1) is a non-selective monoamine transporter (DAT/NET/SERT) agonist. tert-Butylcathinone hydrochloride is promising for research of depressive disorders .

HY-12826

IMB-XH1	Beta-lactamase Bcl-2 Family Bacterial	Cancer
IMB-XH1 is an inhibitor of myeloid cell factor 1 (Mcl-1) . IMB-XH1 is a non-competitive Delhi metallo-β-lactamase (NDM-1) inhibitor. The IC₅₀s of IMB-XH1 against metallo-β-lactamases NDM-1, IMP-4, ImiS and L1 are 0.4637 μM, 3.980 μM, 0.2287 μM and 1.158 μM, respectively .

HY-W145699

D-myo-Inositol 4-monophosphate	Biochemical Assay Reagents Endogenous Metabolite	Others
D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

HY-137724

C-di-IMP Cyclic-di-IMP	STING	Cancer
C-di-IMP (Cyclic-di-IMP) is a STING agonist. C-di-IMP can be used for the research of tumor .

HY-164434

Xanthosine-5'-monophosphate 5'-Xanthylic acid	Endogenous Metabolite	Others
Xanthosine-5'-monophosphate can be obtained by catalyzing inosine 5'-monophosphate (IMP) with inosine 5'-monophosphate dehydrogenase (IMPDH) .

HY-10250

Triciribine phosphate TCN-P	ATP Synthase	Metabolic Disease Cancer
Triciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity .

HY-175488

RPX 7546	Beta-lactamase Bacterial	Infection
RPX 7546 is a potent inhibitor of metallo-𝛽-lactamases (MBLs) with IC₅₀ values of 1.4 and 48 μM for IMP-1 and IMP-78, respectively. RPX 7546 has antibacterial activity .

HY-176519

ANT2681	Beta-lactamase Bacterial	Infection
ANT2681 is a potent NDM inhibitor with a K_i value of 0.04 μM against NDM-1. ANT2681 also inhibits other MBLs, such as VIM-1 and *IMP-1* with K_i values of 0.63 μM and 3.81 μM, respectively. ANT2681 can be used in combination with Meropenem (HY-13678) to inhibit infections caused by NDM-producing Enterobacteriaceae .

HY-W009666

6-Chloro-5-(2-chloroethyl)oxindole	Dopamine Transporter	Others
6-Chloro-5-(2-chloroethyl)oxindole (Imp Z2) is an impurity of Ziprasidone (HY-14542), a substrate of the human dopamine transporter (hDAT) .

HY-136498

T-705RMP	Drug Metabolite	Infection
T-705RMP, a phosphorylated metabolite of T-705, exhibits a very weak inhibitory effect on the IMP dehydrogenase (IMPDH) activities of the host cells, with an IC₅₀ of 601 μM .

HY-178976

YL6113	Beta-lactamase	Infection
YL6113 is a potent and selective dual inhibitor of metallo-β-lactamases (MBLs) and serine-β-lactamases (SBLs). YL6113 shows inhibitory effect to MBLs, such as NDm-1, VIM-2, IMP-1, with IC₅₀ values of 0.25, 27.16 and 3.55 μM. YL6113 shows inhibitory effect to SBLs, such as KPC-2, AmpC, OXA-48, with IC₅₀ values of 0.2, 34.1 and 1.31 μM. YL6113 enhances the antibacterial efficacy of Meropenem (HY-13678) against carbapenem-resistant Gram-negative bacteria. YL6113 can be used for the research of infection .

HY-171112

KSP-1007	Beta-lactamase Bacterial	Infection
KSP-1007 is a bicyclic boronate-based broad-spectrum β-lactamase inhibitor. KSP-1007 can effectively inhibit class A, B, C and D β-lactamases, including serine-type, metallo-type (such as NDM, VIM, IMP) and Acinetobacter baumannii OXA-type enzymes. KSP-1007 can enhance the antibacterial activity of Meropenem (HY-13678), reduce its MIC value, and be effective against carbapenemase-producing Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa. KSP-1007 can be used for the research of bacterial infection .

HY-155470

IMP 243	Biochemical Assay Reagents	Cancer
IMP 243 is a symmetric di-HSG (histamine-succinyl-glycine) bivalent hapten containing a Tscg-Cys ligand and two HSG groups. IMP 243 can be radiolabeled with ^99mTc-pertechnetate. IMP 243 can be conjugated to other peptides to design bispecific antibodies (bsMAbs) for cancer research .

HY-150255

IMP2-IN-3	IGF-1R Insulin Receptor	Cancer
IMP2-IN-3 is a potent IMP2 inhibitor. IMP2-IN-3 shows anticancer effects .

HY-155471

IMP 245	Biochemical Assay Reagents	Others
IMP 245 is a symmetric di-HSG bivalent hapten. IMP 245 has low toxicity, high affinity binding to available antibodies and absence of cross reactivity or non-specific binding with body components .

HY-155469

IMP 241	Hapten	Others
IMP 241 is a di-HSG bivalent hapten .

HY-137724A

*C-di-IMP* disodium** Cyclic-di-IMP disodium	STING	Cancer
C-di-IMP disodium is a STING agonist. C-di-IMP disodium can be used in tumor research .

HY-RS06794

IMP4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IMP4 Human Pre-designed siRNA Set A contains three designed siRNAs for IMP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IMP4 Human Pre-designed siRNA Set A IMP4 Human Pre-designed siRNA Set A

HY-RS06793

IMP3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IMP3 Human Pre-designed siRNA Set A contains three designed siRNAs for IMP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IMP3 Human Pre-designed siRNA Set A IMP3 Human Pre-designed siRNA Set A

HY-RS24431

Imp3 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Imp3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Imp3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Imp3 Rat Pre-designed siRNA Set A Imp3 Rat Pre-designed siRNA Set A

HY-108213S1

Inosinic acid-15N4 dilithium 5'-IMP-15N4 dilithium; IMP-15N4 dilithium; Inosine 5'-dihydrogen phosphate-15N4 dilithium	Isotope-Labeled Compounds	Others
Inosinic acid- ¹⁵N₄ dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is ¹⁵N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-W769319

Inosinic acid-13C5 5'-IMP-13C5; IMP-13C5; Inosine 5'-dihydrogen phosphate-13C5	Isotope-Labeled Compounds Endogenous Metabolite	Others
Inosinic acid- ¹³C₅ (5'-IMP- ¹³C₅) is the ¹³C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-137450A

Senaparib hydrochloride IMP4297 hydrochloride; JS109 hydrochloride	PARP	Cancer
Senaparib hydrochloride (IMP4297 hydrochloride) is an oral, selective PARP1/2 inhibitor with potent anti-tumor activity. Senaparib hydrochloride shows antitumor activity against advanced ovarian cancer .

HY-10250A

Triciribine phosphate sodium TCN-P sodium	ATP Synthase	Metabolic Disease Cancer
Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity .

HY-108213AR

Inosinic acid disodiumhydrate(1:2:X) (Standard) 5'-IMP disodiumhydrate(1:2:X) (Standard); IMP disodiumhydrate(1:2:X) (Standard); Inosine 5'-dihydrogen phosphate disodiumhydrate(1:2:X) (Standard)	Reference Standards Endogenous Metabolite	Others
Inosinic acid (disodium)(hydrate)(1:2:X) (Standard) is the analytical standard of Inosinic acid (disodium)(hydrate)(1:2:X). This product is intended for research and analytical applications. Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

Cat. No.	Product Name	Type

HY-D2188

IMP-2373

Fluorescent Dye

IMP-2373 is a low-toxicity activity-based probe targeting covalent pan-deubiquitinase (DUB), which modulates and monitors DUB activity via covalent binding to the catalytic cysteine and active site of DUB. IMP-2373 enables real-time tracking of dynamic intracellular DUB activity in physiologically relevant living cell systems, and quantitative analysis of activity changes induced by pharmacological inhibition or MYC dysregulation. IMP-2373 can be used for research on related diseases such as B-cell lymphoma .

Cat. No.	Product Name	Type

HY-W145699

D-myo-Inositol 4-monophosphate

Biochemical Assay Reagents

D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

Cat. No.	Product Name	Target	Research Area	Image

HY-P991301

IMP-761	LAG-3	Cancer
IMP-761 is a human IgG4 monoclonal antibody (mAb) targeting CD223/LAG3. IMP-761 binds to D1 of human LAG32. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003) .

HY-P99027

Ieramilimab LAG525; IMP701; Hu5A8	LAG-3	Cancer
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules. Ieramilimab restores T-cell and NK-cell-mediated antileukemic immunity by reducing exhaustion and augmenting cytokine output and cytotoxicity. Ieramilimab increases the infiltration of cytotoxic T lymphocytes and reduces baseline densities of regulatory T cells (Tregs) and ADAM10-expressing tumor cells. Ieramilimab can be used for the study of various malignancies including melanoma, RCC, and advanced solid tumors .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-15310

Ivermectin Maximum Cited Publications 48 Publications Verification MK-933; CD-5024; K-237	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Antiviral Anti-parasitic Disease Research Disease Research Fields Source Classification Cancer	Environmental Pollutants Antibiotic Mitophagy Bacterial Parasite Autophagy Flavivirus HSV HIV SARS-CoV Dengue Virus
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

HY-108213

Inosinic acid 4 Publications Verification 5'-IMP; IMP; Inosine 5'-dihydrogen phosphate	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-D0887

Disodium 5'-inosinate 1 Publications Verification IMP disodium salt; Disodium inosinate	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Disease Research Fields Source Classification Food Research	Others
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .

HY-133157

FAICAR 5-Formamidoimidazole-4-carboxamide ribotide	Source Classification	DNA/RNA Synthesis
FAICAR (5-Formamidoimidazole-4-carboxamide ribotide) is a purine nucleotide and the IMP cyclohydrolase substrate of Cryptococcus neoformans ATIC. It is a key intermediate in the de novo purine synthesis pathway. FAICAR can be used in studies related to Cryptococcus neoformans infection .

HY-108213R

Inosinic acid (Standard) 5'-IMP (Standard); IMP (Standard); Inosine 5'-dihydrogen phosphate (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite	Reference Standards Endogenous Metabolite
Inosinic acid (Standard) is the analytical standard of Inosinic acid. This product is intended for research and analytical applications. Inosinic acid is an endogenous metabolite. Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-129972

Ribavirin 5'-monophosphate dilithium RMP dilithium	Structural Classification Natural Products Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent .

HY-108213A

Inosinic acid disodiumhydrate(1:2:X) 4 Publications Verification 5'-IMP disodiumhydrate(1:2:X); IMP disodiumhydrate(1:2:X); Inosine 5'-dihydrogen phosphate disodiumhydrate(1:2:X)	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-W145699

D-myo-Inositol 4-monophosphate	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Biochemical Assay Reagents Endogenous Metabolite
D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

HY-108213AR

Inosinic acid disodiumhydrate(1:2:X) (Standard) 5'-IMP disodiumhydrate(1:2:X) (Standard); IMP disodiumhydrate(1:2:X) (Standard); Inosine 5'-dihydrogen phosphate disodiumhydrate(1:2:X) (Standard)	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Inosinic acid (disodium)(hydrate)(1:2:X) (Standard) is the analytical standard of Inosinic acid (disodium)(hydrate)(1:2:X). This product is intended for research and analytical applications. Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite. Inosinic acid (disodium)(hydrate)(1:2:X) is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

Species:	Human (7) Rhesus Macaque (1)
Tag:	T7 (1) His (7) Tag Free (1) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701535

	BRAP Protein, Human BRAP; BRCA1-associated protein; BRAP2; IMPedes mitogenic signal propagation; IMP; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; Renal carcinoma antigen NY-REN-63	Human	E. coli
	BRAP protein acts as a negative regulator of MAP kinase activation, inhibits the formation of the Raf/MEK complex, and may inactivate the KSR1 scaffolding protein. As a Ras-responsive E3 ubiquitin ligase, BRAP undergoes autopolyubiquitination upon Ras activation, releasing its inhibitory effect on Raf/MEK complex formation. BRAP Protein, Human is the recombinant human-derived BRAP protein, expressed by E. coli , with tag free.

HY-P70197

	IMPA2 Protein, Human (His) rHuInositol monophosphatase 2/IMPA2, His; Inositol Monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-Monophosphatase 2; Myo-Inositol Monophosphatase A2; IMPA2; IMP.18P	Human	E. coli
	IMPA2, or Inositol monophosphatase 2, demonstrates enzymatic activity by utilizing various substrates such as myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP. Additionally, it has been implicated as the pharmacological target for the action of lithium ions (Li⁺) in the brain. IMPA2 Protein, Human (His) is the recombinant human-derived IMPA2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702799

	IMPDH2 Protein, Human (His) IMP dehydrogenase 2; IMPD 2; IMPDH 2	Human	E. coli
	IMPDH2 Protein, Human (His) is the recombinant human-derived IMPDH2, expressed by E. coli , with C-6*His labeled tag. ,

HY-P70335

	IMPA1 Protein, Human (His) rHuInositol monophosphatase 1/IMPA1, His; Inositol Monophosphatase 1; IMP 1; IMPase 1; Inositol-1(or 4)-Monophosphatase 1; Lithium-Sensitive Myo-Inositol Monophosphatase A1; IMPA1; IMPA	Human	E. coli
	IMPA1 protein provides essential inositol for the synthesis of phosphatidylinositol and polyphosphate inositol. IMPA1 Protein, Human (His) is the recombinant human-derived IMPA1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70950

	IGF2BP2 Protein, Human (T7-His) Insulin-Like Growth Factor 2 mRNA-Binding Protein 2; IGF2 mRNA-Binding Protein 2; IMP-2; Hepatocellular Carcinoma Autoantigen p62; IGF-II mRNA-Binding Protein 2; VICKZ Family Member 2; IGF2BP2; IMP2; VICKZ2	Human	E. coli
	The IGF2BP2 protein is an RNA-binding factor that coordinates the recruitment of target transcripts into cytoplasmic mRNP, promoting mRNA transport and transient storage. It regulates the contact of target transcripts with the translation machinery and protects them from microRNA-mediated degradation. IGF2BP2 Protein, Human (T7-His) is the recombinant human-derived IGF2BP2 protein, expressed by E. coli , with N-T7, C-6*His labeled tag.

HY-P703525

	IGF2BP3 Protein, Human (His) Insulin-like growth factor 2 mRNA-binding protein 3; IGF2 mRNA-binding protein 3; IMP-3; IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer (hKOC); VICKZ family member 3; IGF2BP3; IMP3; KOC1; VICKZ3	Human	E. coli
	IGF2BP3 Protein, Human (His) is the recombinant human-derived IGF2BP3 protein, expressed by E. coli, with N-6*His tag.

HY-P76409

	IGFBP-2 Protein, Rhesus Macaque (HEK293, His) Insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2	Rhesus Macaque	HEK293
	IGFBP‐2 is a member of a family of six insulin‐like growth factor (IGF) binding proteins. IGFBP-2 is the second most abundant IGFBP in the circulation and binds IGF-II with higher affinity than IGF-I. IGFBP-2 has been implicated in the regulation of IGF activity in most tissues and organs. IGFBP-2 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived IGFBP-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74850

	IGF2BP2 Protein, Human (sf9, His-GST) Insulin-like growth factor 2 mRNA-binding protein 2; IMP-2; IGF2BP2; VICKZ2	Human	Sf9 insect cells
	The IGF2BP2 protein is an RNA-binding factor that coordinates the recruitment of target transcripts into cytoplasmic mRNP, promoting mRNA transport and transient storage. It regulates the contact of target transcripts with the translation machinery and protects them from microRNA-mediated degradation. IGF2BP2 Protein, Human (sf9, His-GST) is the recombinant human-derived IGF2BP2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

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Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
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Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-108213S1

Inosinic acid-15N4 dilithium
Inosinic acid- ¹⁵N₄ dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is ¹⁵N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-W769319

Inosinic acid-13C5
Inosinic acid- ¹³C₅ (5'-IMP- ¹³C₅) is the ¹³C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-W769319A

Inosinic acid-13C5 TEA
Inosinic acid- ¹³C₅ (5'-IMP- ¹³C₅) TEA is the ¹³C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs .

HY-178375S

Imidacloprid impurity 1-d4
Imidacloprid impurity 1-d₄ is the deuterium labeled Imidacloprid impurity 1 (HY-131965). Imidacloprid impurity 1 (IMP-2) is the impurity found during the synthesis of Ivermectin (HY-15310) .

Host:	Mouse (7) Rabbit (10)
Reactivity:	Human (17) mouse (1) rat (1) Rat (6) Mouse (9)
Application:	WB FC ICC/IF (1) IHC-P (9) ICC/IF (10) IF-Tissue (1) IP (7) IHC-F (1) WB (16) FC (4) ELISA (3)
Isotype:	IgG (11) IgG1 (3)
Conjugation:	Non-conjugated (17)
Clonality:	Polyclonal (1) Monoclonal (10) Monoclonal Antibody (1) Recombinant (6)
Modification:	Unmodified (12)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83793

	IGF2BP3 Antibody (YA3490) KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3	WB, IHC-P, FC, ELISA	Human
	IGF2BP3 Antibody (YA3490) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IGF2BP3.

HY-P83793A

	IGF2BP3 Antibody (YA3490)(PBS only) KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3	WB, IHC-P, FC, ELISA	Human
	IGF2BP3 Antibody (YA3490) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IGF2BP3.

HY-P85593

	BRAP Antibody (YA5285) 3010002G07Rik; BRAP2; BRCA1 associated protein; Galectin 2 binding protein; IMP; IMPedes mitogenic signal propagation; Renal carcinoma antigen NY REN 63; RING finger protein 52; RNF52; zgc:92894.	WB	Human
	BRAP Antibody (YA5285) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to BRAP.

HY-P85553

	ATIC Antibody (YA5245) 5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase; 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase; 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase; AICARFT; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein PURH; FLJ93545; IMP cyclohydrolase; IMP synthase; IMP synthetase; IMPCHASE; Inosinicase; OK/SW-cl.86; Phosphoribosylaminoimidazolecarboxamide formyltransferase; Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PUR9_HUMAN; PURH.	WB	Human, Mouse, Rat
	ATIC Antibody (YA5245) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to ATIC.

HY-P83326

	IGF2BP1 Antibody (YA3071) insulin-like growth factor 2 mRNA binding protein 1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1	WB, IHC-P, IP	Human, Mouse
	IGF2BP1 Antibody (YA3071) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP1.

HY-P83326A

	IGF2BP1 Antibody (YA3071)(PBS only) insulin-like growth factor 2 mRNA binding protein 1; IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1	WB, IHC-P, IP	Human, Mouse
	IGF2BP1 Antibody (YA3071) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP1.

HY-P80724

	IMP3 Antibody Cancer/testis antigen 98; CT98; DKFZp686F1078; hKOC; IF2B3_HUMAN; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; IGF2 mRNA binding protein 3; IGF2 mRNA-binding protein 3; IGF2BP3; IMP 3; IMP-3; Insulin like growth factor 2 mRNA binding prot	WB, ICC/IF, IP, FC	Human, Mouse, Rat
	IMP3 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to IMP3.

HY-P85226

	IMP-3 Antibody (YA4918) IGF2BP3; IMP3; KOC1; VICKZ3; Insulin-like growth factor 2 mRNA-binding protein 3; IGF2 mRNA-binding protein 3; IMP-3; IGF-II mRNA-binding protein 3; KH domain-containing protein overexpressed in cancer; hKOC; VICKZ family member 3	WB, ICC/IF, IP, FC, IHC-P, IHC-F, IF-Tissue	Human
	IMP-3 Antibody (YA4918) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to IMP-3.

HY-P810469

	ATIC Antibody (YA9768) ATIC, 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase, PURH, IMPCHASE, AICARFT, Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase, AICAR Transformylase/Inosine Monophosphate Cyclohydrolase, Bifunctional Purine Biosynthesis Protein ATIC, 5-Aminoimidazole-4-Carboxamide-1-Beta-D-Ribonucleotide Transformylase/Inosinicase, AICAR Formyltransferase/IMP Cyclohydrolase Bifunctional Enzyme, Epididymis Secretory Sperm Binding Protein Li 70p, Bifunctional Purine Biosynthesis Protein PURH, AICARFT/IMPCHASE, HEL-S-70p, AICAR	WB FC ICC/IF	Human, mouse, rat
	ATIC Antibody (YA9768) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to ATIC.

HY-P81880

	Importin 9/RANBP9 Antibody (YA1625) IMPortin 9; IMP9; Ran-binding protein 9; RanBP9	WB, ICC/IF, IP	Human
	Importin 9/RANBP9 Antibody (YA1625) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Importin 9/RANBP9.

HY-P81880A

	Importin 9/RANBP9 Antibody (YA1625)(PBS only) IMPortin 9; IMP9; Ran-binding protein 9; RanBP9	WB, ICC/IF, IP	Human
	Importin 9/RANBP9 Antibody (YA1625) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Importin 9/RANBP9.

HY-P82288

	IGF2BP2 Antibody (YA2033) IGF2BP2; IMP2; VICKZ2; Insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	IGF2BP2 Antibody (YA2033) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP2.

HY-P82288A

	IGF2BP2 Antibody (YA2033)(PBS only) IGF2BP2; IMP2; VICKZ2; Insulin-like growth factor 2 mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IMP-2; Hepatocellular carcinoma autoantigen p62; IGF-II mRNA-binding protein 2; VICKZ family member 2	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	IGF2BP2 Antibody (YA2033) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2BP2.

HY-P85583

	IMP3 Antibody (YA5275) Cancer/testis antigen 98; CT98; DKFZp686F1078; hKOC; IF2B3_HUMAN; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; IGF2 mRNA binding protein 3; IGF2 mRNA-binding protein 3; IGF2BP3; IMP 3; IMP-3; Insulin like growth factor 2 mRNA binding protein 3; Insulin-like growth factor 2 mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; KOC 1; KOC1; VICKZ 3; VICKZ family member 3; VICKZ3.	IHC-P, WB, ICC/IF, ELISA	Human, Mouse
	IMP3 Antibody (YA5275) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to IMP3.

HY-P82241

	TNPO3 Antibody (YA1986) TNPO 3; IMP12; IMPortin 12; IPO12; MTR10A; TNPO3; Transportin 3; Transportin SR; TRN-SR2; TRNSR	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	TNPO3 Antibody (YA1986) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TNPO3.

HY-P82250

	RanBP9 Antibody (YA1995) B cell antigen receptor Ig beta associated protein 1; BPM 90; BPM L; BPM-L; BPM90; BPML; IBAP 1; IMP 9; IMPortin 9; Novel centrosomal protein RanBPM; RAN binding protein 9; Ran binding protein centrosomal; Ran Binding Protein in the Microtubule organizing center; Ran binding protein M; Ran BP9; Ran-binding protein 9; Ran-binding protein M; RANB9_HUMAN; RanBP 7; RANBP 9; RanBP7; RanBP9; RanBPM.	WB, ICC/IF	Human, Mouse, Rat
	RanBP9 Antibody (YA1995) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RanBP9.

HY-P85542

	RanBP9 Antibody (YA5234) B cell antigen receptor Ig beta associated protein 1; BPM 90; BPM L; BPM-L; BPM90; BPML; IBAP 1; IMP 9; IMPortin 9; Novel centrosomal protein RanBPM; RAN binding protein 9; Ran binding protein centrosomal; Ran Binding Protein in the Microtubule organizing center; Ran binding protein M; Ran BP9; Ran-binding protein 9; Ran-binding protein M; RANB9_HUMAN; RanBP 7; RANBP 9; RanBP7; RanBP9; RanBPM.	WB, ICC/IF, IP	Human
	RanBP9 Antibody (YA5234) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to RanBP9.

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Cat. No.	Product Name		Classification

HY-138995

IMP-1710 1 Publications Verification		Alkynes
IMP-1710 is a potent and selective deubiquitylating enzyme UCHL1 inhibitor with an IC₅₀ value of 38 nM. IMP-1710 has antifibrotic activity. IMP-1710 is a UCHL1 probe to identify and quantify target proteins in intact human cells . IMP-1710 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IMP-1710 can be used in the research of idiopathic pulmonary fibrosis .

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