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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

IgG1-κ antibody

" in MedChemExpress (MCE) Product Catalog:

671

Inhibitors & Agonists

4

Fluorescent Dyes

824

Inhibitory Antibodies

10

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P9999
    Trontinemab

    RG6102; RO-7126209

    		 Amyloid-β Neurological Disease
    Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human TFR1 .
    Trontinemab
  • HY-P9901
    Ipilimumab
    4 Publications Verification

    MDX-010; BMS-734016

    		 CTLA-4 Cancer
    Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies .
    Ipilimumab
  • HY-P9909
    Ustekinumab
    4 Publications Verification

    CNTO-1275; L04AC05; TT-20

    		 Interleukin Related Inflammation/Immunology Cancer
    Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.
    Ustekinumab
  • HY-P990007
    Tulisokibart

    PRA023

    		 TNF Receptor Inflammation/Immunology
    Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody. Tulisokibart targets to TNFSF15/TL1A. Tulisokibart can be used to study a variety of inflammatory/fibrotic diseases, such as Crohn's Disease (CD) and ulcerative colitis .
    Tulisokibart
  • HY-P9966
    Enoblituzumab
    1 Publications Verification

    MGA271

    		 CD276/B7-H3 Cancer
    Enoblituzumab (MGA271) is a humanized IgG1κ monoclonal antibody recognizing human B7-H3 protein, a member of the B7 family of immune regulators .
    Enoblituzumab
  • HY-P99778
    Ontuxizumab

    MORAb-004

    		 EGFR Cancer
    Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer .
    Ontuxizumab
  • HY-P99979
    Rat IgG1 kappa, Isotype Control
    2 Publications Verification

    		 Fc Receptor (FcR) Inflammation/Immunology
    Rat IgG1 kappa, Isotype Control, a rat monoclonal antibody, is an isotype control for Rat IgG1κ antibody.
    Rat IgG1 kappa, Isotype Control
  • HY-P990591
    GSK-1070806

    Aletekitug

    		 Interleukin Related Inflammation/Immunology
    GSK-1070806 (Aletekitug) is a humanized IgG1/κ monoclonal antibody targeting IL-18. GSK-1070806 neutralizes IL-18 activity.GSK-1070806 can be used for the research of inflammation. The isotype control for GSK-1070806 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001) .
    GSK-1070806
  • HY-P9993
    Peresolimab
    1 Publications Verification

    LY-3462817

    		 PD-1/PD-L1 Inflammation/Immunology
    Peresolimab is a humanized IgG1-κ antibody targeting to PD-1. Peresolimab potentially stimulates physiological immune inhibitory pathways to restore immune homeostasis. Peresolimab can be used in research of rheumatoid arthritis .
    Peresolimab
  • HY-P991728
    Zarutatug

    TORL-3-600 antibody

    		 Cadherin ADC Antibody Cancer
    Zarutatug (TORL-3-600 antibody) is an IgG1κ humanized antibody targeting cadherin 17 (CDH17). It selectively binds to cell-surface CDH17, triggering endocytosis and trafficking to lysosomes. Zarutatug can be used to construct ADCs, such as TORL-3-600 .
    Zarutatug
  • HY-P99368
    Lacnotuzumab

    MCS110

    		 c-Fms Metabolic Disease Cancer
    Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis .
    Lacnotuzumab
  • HY-P990906
    Bosakitug

    BSI-045B; TQC2731

    		 Interleukin Related Inflammation/Immunology
    Bosakitug (BSI-045B) is an TSLP-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Bosakitug can be used in the research of inflammatory diseases such as moderate to severe atopic dermatitis .
    Bosakitug
  • HY-P991280
    BMS-981164

    		Interleukin Related Inflammation/Immunology
    BMS-981164 is a human anti-IL31 IgG1-κ monoclonal antibody. BMS-981164 effectively inhibits the IL-31 signaling pathway. The isotype control of BMS-981164 can be referenced to Human IgG1 kappa, Isotype Control (HY-P99001). BMS-981164 is applicable to research related to atopic dermatitis .
    BMS-981164
  • HY-P99181
    Mupadolimab

    CPI-006

    		 CD73 Infection Inflammation/Immunology Cancer
    Mupadolimab (CPI-006) is an IgG1κ humanized FcγR binding-deficient anti-CD73 monoclonal antibody (mAb) that activates CD73 POS B cells .
    Mupadolimab
  • HY-P990933
    Ocankitug

    CM-326

    		 Interleukin Related Inflammation/Immunology
    Ocankitug (CM-326) is a humanized IgG1κ antibody targeting thymic stromal lymphopoietin (TSLP). It can be used for research on type 2 inflammatory respiratory diseases, including moderate to severe asthma, chronic sinusitis with nasal polyps, etc.
    Ocankitug
  • HY-P99899
    Samrotamab

    PR-1498487

    		 ADC Antibody Cancer
    Samrotamab (PR-1498487) is a humanized IgG1-κ chimeric antibody targeting LRRC15. Samrotamab markedly reduces bladder cancer cells viability and inhibits clonogenic growth, migratory and invasive capabilities. Samrotamab significantly increases LRRC15 mRNA level while suppressing SCG5 mRNA expression. Samrotamab can be used for synthesis of ADC ABBV-085 .
    Samrotamab
  • HY-P99424
    Afasevikumab

    RG 7624; RO 5553110; NI-1401

    		 Interleukin Related Inflammation/Immunology
    Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities .
    Afasevikumab
  • HY-P99313
    Quilizumab

    Anti-Human IGHE Recombinant antibody

    		 Apoptosis Inflammation/Immunology
    Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed IGHE/IgE, leading to IGHE/IgE switching and memory B cell depletion. Quilizumab has potential in asthma research .
    Quilizumab
  • HY-P991707
    Notiretatug

    SHR-A2102 antibody

    		 Nectin-4 Cancer
    Notiretatug is a humanized IgG1κ antibody targeting Nectin-4. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
    Notiretatug
  • HY-P990053
    Nelistotug

    GSK-6097608

    		 Small Interfering RNA (siRNA) Inflammation/Immunology Cancer
    Nelistotug (GSK 6097608; GSK6097608) is a human IgG1κ antibody targeting CD96 .
    Nelistotug
  • HY-P991703
    Mocertatug

    GSK5733584 antibody; HS-20089 antibody; hu2F7

    		 CD276/B7-H3 Cancer
    Mocertatug (GSK5733584 antibody) is a humanized IgG1κ antibody targeting B7-H4/VTCN1. Mocertatug can be used to construct ADCs, such as Mocertatug Rezetecan (HY-185280) .
    Mocertatug
  • HY-P99040
    Onvatilimab
    1 Publications Verification

    JNJ-61610588; CI-8993; VSTB112

    		 VISTA Cancer
    Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .
    Onvatilimab
  • HY-P99591
    Sontuzumab

    AS1402; huHMFG-1; Epitumomab

    		 Mucin Cancer
    Sontuzumab (AS1402) is a humanizedised IgG1κ MUC1 specific monoclonal antibody. Sontuzumab binds the extracellular MUC1 peptide sequence PDTR with a Kd of ~1 nM. Sontuzumab can be used for the research of breast cancer .
    Sontuzumab
  • HY-P991699
    Lixarkitug

    AZD9829 antibody; INT-020

    		 ADC Antibody Interleukin Related Cancer
    Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML) . The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).
    Lixarkitug
  • HY-P991723
    Varsetatug

    CX-2051 antibody

    		 ADC Antibody Transmembrane Glycoprotein Cancer
    Varsetatug (CX-2051 antibody) is a humanized IgG1κ monoclonal antibody inhibitor targeting EpCAM/TROP1/CD326. Varsetatug serves as the antibody component of the ADC compound CX-2051. It can be used in research on cancers including breast cancer, prostate cancer and ovarian cancer .
    Varsetatug
  • HY-P99669
    Iratumumab

    MDX-060

    		 TNF Receptor Cancer
    Iratumumab (MDX-060) a human anti-CD30 IgG1κ monoclonal antibody. Iratumumab inhibits the growth of CD30-expressing tumor cells. Iratumumab can be used for research of Hodgkin's lymphoma (HL) and anaplastic large-cell lymphoma (ALCL) .
    Iratumumab
  • HY-P990689
    Zifibancimig

    RO-7250284

    		 VEGFR Inflammation/Immunology
    Zifibancimig is an anti-VEGFA/ANGPT2 IgG1κ monoclonal antibody .
    Zifibancimig
  • HY-P990024
    Casdozokitug

    SRF-388

    		 Interleukin Related Cancer
    Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27 .
    Casdozokitug
  • HY-P99699
    Lesofavumab

    MHAB5553A; RG70026

    		 Influenza Virus Infection
    Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody .
    Lesofavumab
  • HY-P990898
    Amlenetug

    Lu-AF82422

    		 Sodium Channel Inflammation/Immunology
    HY-P990898 is an SNCA-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Amlenetug
  • HY-P990996
    Felmetatug

    		CD276/B7-H3 Inflammation/Immunology
    HY-P990996 is an VTCN1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Felmetatug
  • HY-P9998
    Semzuvolimab

    UB421

    		 HIV Cancer
    Semzuvolimab is a human IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4). Human CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection .
    Semzuvolimab
  • HY-P99544
    Tagitanlimab

    HBM-9167; KL-A167

    		 PD-1/PD-L1 Cancer
    Tagitanlimab (HBM-9167) is a humanized anti-PD-L1 antibody (IgG1κ type). Tagitanlimab selectively blocks the interaction of PD-L1 and PD-1. Tagitanlimab has the potential to be studied in recurrent or metastatic nasopharyngeal carcinoma (NPC) .
    Tagitanlimab
  • HY-P99727
    Mazorelvimab

    CTB012

    		 RABV Infection
    Mazorelvimab (CTB012) is an anti-rabies humanized IgG1κ monoclonal antibody that binds to the non-overlapping epitopes on the rabies virus (RABV) glycoprotein. Mazorelvimab binds to highly discontinuous conserved residues that are not in or near antigenic site III. Mezagitamab has potential application in the prevention of rabies .
    Mazorelvimab
  • HY-P9988
    Mecbotamab

    BA301

    		 ADC Antibody TAM Receptor Cancer
    Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .
    Mecbotamab
  • HY-P990929
    Misitatug

    RC-88 antibody

    		 Mesothelin Inflammation/Immunology
    HY-P990929 is an MSLN-targeting IgG1κ type chimeric antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Misitatug
  • HY-P991693
    Ipsoprubart

    ELA-026

    		 CD47 Inflammation/Immunology
    Ipsoprubart is a humanized IgG1κ antibody targeting SIRPa/CD172a. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
    Ipsoprubart
  • HY-P990977
    Bulumtatug

    MW282 mAb

    		 Nectin-4 Inflammation/Immunology
    HY-P990977 is an Nectin-4-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Bulumtatug
  • HY-P990904
    Azirkitug

    PR-1925514

    		 CCR Inflammation/Immunology
    HY-P990904 is an CCR8-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Azirkitug
  • HY-P990918
    Emiltatug

    XMT-1604; XMT-1660 antibody

    		 CD276/B7-H3 Inflammation/Immunology
    HY-P990918 is an VTCN1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Emiltatug
  • HY-P990941
    Rinatabart

    		Antifolate Inflammation/Immunology
    HY-P990941 is an FOLR1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Rinatabart
  • HY-P990908
    Cafelkibart

    LM-108

    		 CCR Inflammation/Immunology
    HY-P990908 is an CCR8-targeting IgG1κ type chimeric antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Cafelkibart
  • HY-P991010
    Nebokitug

    CM101

    		 CCR Inflammation/Immunology
    HY-P991010 is an CCL24-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Nebokitug
  • HY-P99310
    Perakizumab

    RG4934

    		 Interleukin Related Inflammation/Immunology
    Perakizumab (RG4934) is a humanized IgG1κ monoclonal antibody against IL-17A (Interleukin Related). Perakizumab can be uesd for the research of autoimmune diseases, such as psoriatic arthritis .
    Perakizumab
  • HY-P990057
    Picankibart

    IBI-112

    		 Interleukin Related Cancer
    Picankibart is a human-derived IgG1κ antibody targeting IL23A. Picankibart specifically binds to the IL23 p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.
    Picankibart
  • HY-P99869
    Ebdarokimab

    		Interleukin Related Others
    Ebdarokimab (AK101) is a humanized IgG1-κ antibody, usually expressed in CHO (Chinese Hamster Ovary) cells .
    Ebdarokimab
  • HY-P99888
    Pimurutamab

    		EGFR Others
    Pimurutamab is a humanized IgG1-κ antibody targeting EGFR. Mainly expressed by CHO-K1 cells .
    Pimurutamab
  • HY-P990085
    Verzistobart

    INCAGN02390

    		 Tim3 Infection
    Verzistobart is an IgG1κ antibody targeting the hepatitis A virus cellular receptor HAVCR2.
    Verzistobart
  • HY-P990994
    Emunkitug

    HFB-200301

    		 TNF Receptor Inflammation/Immunology
    HY-P990994 is an TNFRSF1B-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
    Emunkitug
  • HY-P990040
    Exlinkibart

    LVGN-6051

    		 TNF Receptor Cancer
    Exlinkibart (LVGN-6051) targets TNFRSF9 and is an IgG1κ antibody humanized through complementarity-determining region (CDR) grafting technology.
    Exlinkibart

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