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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
70 Results for "
IgM
" in MedChemExpress (MCE) Product Catalog:
Products (70)
70 Results for "IgM" in MCE Product Catalog:
6
1
1 Cited Publications
Cat. No.: HY-W020658
CAS No.: 97281-52-2
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1
Cat. No.: HY-P99901
CAS No.: 2382896-07-1
Synonyms: VIS649
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Cat. No.: HY-170333
CAS No.: 2996998-09-3
Synonyms: CICL1
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Lipid A-11 (Compound A-11) (CICL1) is an ionizable cationic lipid. Lipid A-11 can be used to prepare lipid nanoparticles. Lipid A-11 can be used in research involving T cell-targeted transfection .
Cat. No.: HY-P990070
CAS No.: 2642175-46-8
Synonyms: BION-1301
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Cat. No.: HY-160719
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NHS-activated 2-octynoic acid-BSA is an immunogen used to establish a mouse model of primary biliary cholangitis (PBC). When used in combination with Complete Freund's Adjuvant (HY-153808), NHS-activated 2-octynoic acid-BSA stimulates the body's immune system, which recognizes it as a foreign antigen and triggers an immune response against autologous biliary epithelial cells. This leads to the production of anti-PDC-E2 antibodies, causing bile duct damage and inflammation. NHS-activated 2-octynoic acid-BSA is promising for use in primary biliary cholangitis research .
Synonyms: HR325
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Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
Cat. No.: HY-P99214
CAS No.: 885053-97-4
Synonyms: KBPA101
Cat. No.: HY-P991086
Synonyms: PRV-3279
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Cat. No.: HY-111782
CAS No.: 26001-38-7
Synonyms: 8-Thioguanosine
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8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll .
Cat. No.: HY-P990299
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Cat. No.: HY-120471
CAS No.: 1259522-94-5
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AM-0687 is a selective inhibitor for PI3Kδ with an IC50 of 2.9 nM. AM-0687 decreases the levels of IgG and IgM specific antibodies, inhibits the anti-IgM/CD40L-induced proliferation of human B cell (IC50=0.8 nM) and the phosphorylation of AKT (IC50=0.7 nM), and exhibits anti-inflammatory efficacy .
Cat. No.: HY-120255
CAS No.: 155976-53-7
Synonyms: 17(R)-HDoHE
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17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .
Cat. No.: HY-P99660
CAS No.: 2573121-53-4
Synonyms: IgM-2323
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Cat. No.: HY-124605
CAS No.: 1630804-24-8
IQS-019 is a B cell receptor (BCR) kinase inhibitor. IQS-019 can inhibit the de-phosphorylation of constitutive and IgM-activated Syk, Lyn, and Btk. IQS-019 can inhibit cell proliferation, migration and induce apoptosis. IQS-019 exhibits antitumor activity and can be used for the research of cancer, such as B cell lymphoma .
Cat. No.: HY-P990162
Synonyms: AB1-2
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Cat. No.: HY-P990901
CAS No.: 2796349-94-3
Synonyms: IgM-8444
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Cat. No.: HY-RS22206
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Ighm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ighm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
