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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
81 Results for "
IgM
" in MedChemExpress (MCE) Product Catalog:
Products (81)
81 Results for "IgM" in MCE Product Catalog:
6
2
2 Cited Publications
Cat. No.: HY-P72717
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD5L; CT-2; Prev. API6; Apoptosis Inhibitor Of Macrophage; Spalpha; CD5 Molecule-Like; CD5 Antigen-Like (Scavenger Receptor Cysteine Rich Family); SP-ALPHA; Apoptosis Inhibitor Expressed By Macrophages; SP-Alpha; IgM-Associated Peptide; PRO229; Apoptosis
Species:
Mouse
Source:
HEK293
1
Target:
Research Areas:
1
1
1 Cited Publications
Cat. No.: HY-P7144
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (Ligand) Superfamily Member 5; Prev. HIgM1; Tumor Necrosis Factor Ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen Ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
Species:
Human
Source:
E. coli
Synonyms: HR325
Research Areas:
Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH). Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 µM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor .
Cat. No.: HY-P99214
CAS No.: 885053-97-4
Synonyms: KBPA101
Cat. No.: HY-113553
CAS No.: 102185-28-4
Synonyms: (p-Aminophenyl)phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC
Target:
Research Areas:
4-Aminophenylphosphorylcholine ((p-Aminophenyl) phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC) is a phosphatidylcholine derivative that serves as a coupling ligand and antigen probe. When conjugated with gold nanoclusters, the phosphocholine head epitope of 4-Aminophenylphosphorylcholine is specifically recognized by anti-Pc IgM and CRP. It can be covalently coupled to human serum albumin (HSA) or glutathione-protected gold nanoclusters (Au-GSH) via covalent chemistry, respectively. The 4-Aminophenylphosphorylcholine-HSA complex acts as an ELISA coating antigen for detecting endogenous anti-Pc IgM antibodies in plasma; 4-Aminophenylphosphorylcholine-modified Au-GSH can be used to construct an ultra-stealthy NIR-II fluorescent gold nanocluster probe for imaging-related studies in mouse breast cancer and colon cancer models .
Cat. No.: HY-111782
CAS No.: 26001-38-7
Synonyms: 8-Thioguanosine
Target:
Research Areas:
8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll .
Cat. No.: HY-P990299
Target:
Research Areas:
Cat. No.: HY-120471
CAS No.: 1259522-94-5
Target:
Research Areas:
AM-0687 is a selective inhibitor for PI3Kδ with an IC50 of 2.9 nM. AM-0687 decreases the levels of IgG and IgM specific antibodies, inhibits the anti-IgM/CD40L-induced proliferation of human B cell (IC50=0.8 nM) and the phosphorylation of AKT (IC50=0.7 nM), and exhibits anti-inflammatory efficacy .
Cat. No.: HY-120255
CAS No.: 155976-53-7
Synonyms: 17(R)-HDoHE
Target:
Research Areas:
17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .
Cat. No.: HY-P99660
CAS No.: 2573121-53-4
Synonyms: IgM-2323
Research Areas:
Cat. No.: HY-124605
CAS No.: 1630804-24-8
IQS-019 is a B cell receptor (BCR) kinase inhibitor. IQS-019 can inhibit the de-phosphorylation of constitutive and IgM-activated Syk, Lyn, and Btk. IQS-019 can inhibit cell proliferation, migration and induce apoptosis. IQS-019 exhibits antitumor activity and can be used for the research of cancer, such as B cell lymphoma .
Cat. No.: HY-P990901
CAS No.: 2796349-94-3
Synonyms: IgM-8444
Target:
Research Areas:
Cat. No.: HY-P990162
Synonyms: AB1-2
Target:
Research Areas:
Cat. No.: HY-RS22206
Target:
Research Areas:
Ighm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ighm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16527
Target:
Research Areas:
Cd40 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd40 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02247
Target:
Research Areas:
CD40LG Human Pre-designed siRNA Set A contains three designed siRNAs for CD40LG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-118374
CAS No.: 1338483-10-5
Research Areas:
AM-9635 is a selective PI3Kδ inhibitor with oral bioavailability, good in vitro and in vivo activity and pharmacodynamic properties. AM-9635 inhibits PI3Kδ-dependent B cell receptor-mediated AKT phosphorylation and suppresses the production of specific IgG and IgM antibodies in rats immunized with Aplysia leocyanin (KLH).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
