28 Results for "

Lipoamide

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "Lipoamide" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-B1142
CAS No.: 940-69-2
Synonyms: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .
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1
1 Cited Publications
Cat. No.: HY-P1103
CAS No.: 1030384-98-5
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-P1103A
Target:  

CXCR

Research Areas:  

Cancer

CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .
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Cat. No.: HY-P2800A
CAS No.: 9001-18-7
Research Areas:  

Metabolic Disease

Diaphorase, Clostridium sp. is a diaphorase derived from Clostridium sp. As a flavin-containing NAD (P) H dehydrogenase, Diaphorase, Clostridium sp. uses NADH as an electron donor to reduce artificial dyes such as DCPIP and NBT, and participates in energy metabolism .
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Cat. No.: HY-P11293
CAS No.: 1309855-53-5
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .
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Cat. No.: HY-P4757
CAS No.: 108081-77-2
Target:  

Parasite

Research Areas:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Cat. No.: HY-P1321
CAS No.: 158859-98-4
Synonyms: 1229U91; GW1229
Research Areas:  

Neurological Disease

GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pKi= 8.8) .
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Cat. No.: HY-141338
CAS No.: 1314378-19-2
Purity:  99.61%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Lipoamide-PEG3-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-141339
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Lipoamide-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-E70340
Research Areas:  

Others

Lipoamide dehydrogenase, porcine is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
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Cat. No.: HY-P1321A
Synonyms: 1229U91 TFA; GW1229 TFA
Research Areas:  

Neurological Disease

GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pKi of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC50=8.6; pKi=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pKi= 8.8) .
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Cat. No.: HY-N19829
CAS No.: 1173985-69-7
Target:  

Others

Lipoamide B is a lipoic acid amide present in marine Bacillus pumilus (SP21) .
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Cat. No.: HY-N19828
CAS No.: 1173985-68-6
Target:  

Others

Lipoamide A is a natural lipoic acid product isolated from marine Bacillus pumilus (SP21) .
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Cat. No.: HY-P81949
Synonyms: Diaphorase; DihydroLipoamide dehydrogenase; DLDD; DLDH; GCSL; LAD; Lipoamide dehydrogenase; Lipoamide reductase; Lipoyl dehydrogenase; PHE3

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81949A
Synonyms: Diaphorase; DihydroLipoamide dehydrogenase; DLDD; DLDH; GCSL; LAD; Lipoamide dehydrogenase; Lipoamide reductase; Lipoyl dehydrogenase; PHE3

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85504
Synonyms: mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase; Lipoamide; alpha 1; Pyruvate dehydrogenase complex, E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 component subunit alpha; Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; somatic form.

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse

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Cat. No.: HY-P74207
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; BCKAD-E2; DBT
Species:  
Source:  
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Cat. No.: HY-P11480
CAS No.: 3105660-96-3
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC50: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .
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Cat. No.: HY-P702948
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDH kinase; [3-methyl-2-oxobutanoate dehydrogenase [Lipoamide]] kinase; mitochondrial
Species:  
Source:  
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