21 Results for "

MICA

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "MICA" in MCE Product Catalog:

Cat. No.: HY-155311
NKG2D-IN-1 (compound 21) is a natural killer group 2D receptor (NKG2D) inhibitor. NKG2D-IN-1 inhibits the protein-protein interaction between NKG2D and its ligands MICA and ULBP6, with IC50 values of 0.3 μM and 0.7 μM. NKG2D-IN-1 can be used in the research of autoimmune diseases .
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Cat. No.: HY-155312
Research Areas:  

Cancer

NKG2D-IN-2 (compound 47) is a natural killer group 2D receptor (NKG2D) inhibitor with IC50s of 0.1 µM and 0.2 µM in NKG2D/MICA and ULBP6 TR-FRET assays, respectively .
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Cat. No.: HY-151782
CAS No.: 2250437-45-5
Target:  

ADC Linkers

Research Areas:  

Others

The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No.: HY-RS08424
Research Areas:  

Others

MICA Human Pre-designed siRNA Set A contains three designed siRNAs for MICA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-101780A
CAS No.: 1793059-58-1
Synonyms: EDO-S101 hydrochloride; NL-101 hydrochloride
Target:  

HDAC

Research Areas:  

Cancer

Tinostamustine hydrochloride (EDO-S101 hydrochloride) is a compound with anti-multiple myeloma activity and the ability to promote CD38 expression. Tinostamustine hydrochloride enhances the sensitivity of tumor cells to the anti-CD38 monoclonal antibody daratumumab by increasing the acetylation level of histone H3. Tinostamustine hydrochloride can increase the expression of MICA and MICB, thereby activating NK cells. Tinostamustine hydrochloride can significantly delay tumor growth and improve the survival rate of mice .
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Cat. No.: HY-P700790
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704225
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P83760
Synonyms: HLA class I antigen antibody; FLJ36918 antibody; FLJ60820 antibody; MGC111087 antibody; MGC21250 antibody; MHC class I chain related gene A protein antibody; MIC A antibody; MICA antibody; MICA_HUMAN antibody; OTTHUMP00000029088 antibody; PERB11.1 antibody; Stress inducible class I homolog antibody; MHC class I chain related protein B antibody; MICB antibody MICB_HUMAN antibody PERB11.2 antibody Stress inducible class I homolog antibody

Host:  

Rabbit

Application:  

WB, IP, FC

Reactivity:  

Human

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Cat. No.: HY-P75928
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704788
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class I Related Chain A Isoform D; MHC Class I Chain-Related Protein A; MHC Class I Related Chain A Isoform A; Stress Inducible Class I Homolog; MHC Class I Chain-Related A Antigen; MHC Class I Related Sequence A; MHC Class I Chain-Related Protein; MIC-A; MHC Class I Related Chain A; Truncated Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class I-Related Chain A; Major Histocompatibility Complex Class I Chain-Related A; HLA Class I Antigen; Truncated MHC Class I Polypeptide-Related Sequence A; MHC Class I Antigen; Truncated MHC Class I Polypeptide-Related Protein A; Truncated MICA; Truncated MHC Class I Chain-Related Protein A; MICA Protein; MHC Class I Polypeptide-Related Protein A
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704964
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class I Related Chain A Isoform D; MHC Class I Chain-Related Protein A; MHC Class I Related Chain A Isoform A; Stress Inducible Class I Homolog; MHC Class I Chain-Related A Antigen; MHC Class I Related Sequence A; MHC Class I Chain-Related Protein; MIC-A; MHC Class I Related Chain A; Truncated Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class I-Related Chain A; Major Histocompatibility Complex Class I Chain-Related A; HLA Class I Antigen; Truncated MHC Class I Polypeptide-Related Sequence A; MHC Class I Antigen; Truncated MHC Class I Polypeptide-Related Protein A; Truncated MICA; Truncated MHC Class I Chain-Related Protein A; MICA Protein; MHC Class I Polypeptide-Related Protein A
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70157
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70579
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77997
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705233
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77998
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MICA; MHC Class I Related Chain A Isoform B1; MHC Class I Polypeptide-Related Sequence A; MHC Class I Related Chain A Isoform B2; PERB11.1; MHC Class I Related Chain A Isoform C; Major Histocompatibility Complex Class I Chain-Related Protein A; MHC Class
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703442
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Isocitrate lyase 1; EC:4.1.3.1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC:4.1.3.30; icl1; MT0483
Species:  
Others
Source:  
E. coli
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Cat. No.: HY-P992391
Synonyms: IPH43

Research Areas:  

Cancer

IPH4301 is a monoclonal antibody targeting MICA/B, with dual activities of cytotoxicity and immunoregulation . IPH4301 blocks the interaction between MICA/B and NKG2D, inhibits their hydrolysis into soluble sMICA/B, and mediates antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis against tumor cells expressing MICA/MICB. IPH4301 restores the expression and function of NKG2D on primary NK cells and T cells, reverses the immunosuppression induced by M2 macrophages, and enhances NK cell-mediated tumor cell apoptosis. IPH4301 can be used in research related to cancer and triple-negative breast cancer .
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Cat. No.: HY-P81719
Synonyms: PERB11.1; MICA; HLA class I antigen antibody; FLJ36918 antibody; FLJ60820 antibody; MGC111087 antibody; MGC21250 antibody; MHC class I chain related gene A protein antibody

Host:  

Rabbit

Application:  

WB, IP, FC

Reactivity:  

Human

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