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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
MSN
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "MSN" in MCE Product Catalog:
39
39 Publications Verification
Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis . Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .
39
39 Publications Verification
Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis . Rhosin promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .
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4 Cited Publications
Target:
Forschungsgebiete:
MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity .
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1 Cited Publications
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MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection .
Synonyms: mPEG10000-NH2
Art. -Nr.: HY-42984
CAS. Nr.: 916753-62-3
Art. -Nr.: HY-174929A
Synonyms: DBCO-PEG5000-NH2
Art. -Nr.: HY-P1386
CAS. Nr.: 251939-41-0
Synonyms: Dynamin II (828–842)
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Forschungsgebiete:
Art. -Nr.: HY-RS18452
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Forschungsgebiete:
Msn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Msn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-149410
CAS. Nr.: 1314798-31-6
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Forschungsgebiete:
MSN8C, an analog of mansonone E, is a novel catalytic inhibitor of human DNA topoisomerase II. MSN8C induces cancer cell apoptosis. MSN8C shows significant anti-tumor cell proliferation activity in vitro .
Art. -Nr.: HY-174929
Synonyms: DBCO-PEG3400-NH2
Art. -Nr.: HY-RS08723
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Forschungsgebiete:
MSN Human Pre-designed siRNA Set A contains three designed siRNAs for MSN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS24933
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Forschungsgebiete:
Msn Rat Pre-designed siRNA Set A contains three designed siRNAs for Msn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
