383 Results for "

N-Acetyl-

" in MedChemExpress (MCE) Product Catalog:
Products (383)

383 Results for "N-Acetyl-" in MCE Product Catalog:

757
757 Publications Verification
Cat. No.: HY-B0215
CAS No.: 616-91-1
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
Acetylcysteine (N-Acetylcysteine) is a mucolytic agent that can cross the blood-brain barrier, which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine ​​is the most stable form of cysteine ​​during drug delivery and can be used in disulfidptosis studies .
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149
149 Cited Publications
Cat. No.: HY-B0075
CAS No.: 73-31-4
Synonyms: N-Acetyl-5-methoxytryptamine
Melatonin is a hormone made by the pineal gland that can activate melatonin receptor and inhibit PANoptosis. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties . Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation . Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress .
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14
14 Cited Publications
Cat. No.: HY-134495
CAS No.: 59587-09-6
Purity:  98.26%
Synonyms: N-Acetylcysteine ethyl ester; NACET
Research Areas:  

Metabolic Disease

N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .
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11
11 Cited Publications
Cat. No.: HY-127090
CAS No.: 53678-77-6
Purity:  ≥98.0%
Synonyms: MDP
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .
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7
7 Cited Publications
Cat. No.: HY-121526
CAS No.: 67776-06-1
Purity:  98.76%
Synonyms: SNAP
Target:  

NO Synthase

Research Areas:  

Cardiovascular Disease Cancer

S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation .
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4
4 Cited Publications
Cat. No.: HY-125798
CAS No.: 24967-27-9
Purity:  ≥98.0%
Synonyms: Neu5Ac2en; DANA
Target:  

Influenza Virus

Research Areas:  

Infection

N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .
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4
4 Cited Publications
Cat. No.: HY-P2161B
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
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3
3 Cited Publications
Cat. No.: HY-A0132
CAS No.: 7512-17-6
Synonyms: N-Acetyl-2-amino-2-deoxy-D-glucose
N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits .
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3
3 Cited Publications
Cat. No.: HY-107854
CAS No.: 1210-83-9
Purity:  99.96%
Synonyms: N-Acetylserotonin; Normelatonin; O-Demethylmelatonin
N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor.
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3
3 Cited Publications
Cat. No.: HY-136386
CAS No.: 26117-28-2
Purity:  ≥97.0%
Research Areas:  

Inflammation/Immunology

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
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2
2 Cited Publications
Cat. No.: HY-125039
CAS No.: 1287585-40-3
Purity:  99.57%
N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation .
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2
2 Cited Publications
Cat. No.: HY-W012499
CAS No.: 65-82-7
Synonyms: N-Acetylmethionine
N-Acetyl-L-methionine is a dietary supplementation. N-Acetyl-L-methionine increases caspase-3 activity and inhibits mitochondrial activity. N-Acetyl-L-methionine promotes lactation and improves meat quality .
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2
2 Cited Publications
Cat. No.: HY-139093A
CAS No.: 1331891-93-0
Purity:  ≥99.0%
Synonyms: APAP-Cys TFA
Target:  

Drug Derivative

Research Areas:  

Others

Paracetamol-cysteine TFA (APAP-Cys TFA) is a cysteine adduct of Acetaminophen (HY-66005). It forms when Acetaminophen is oxidized to the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) .
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2
2 Cited Publications
Cat. No.: HY-104050
CAS No.: 281224-40-6
Purity:  99.79%
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM .
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1
1 Cited Publications
Cat. No.: HY-113524
CAS No.: 997-55-7
Purity:  99.45%
N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease) .
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1
1 Cited Publications
Cat. No.: HY-101411
CAS No.: 3025-96-5
Purity:  ≥98.0%
Synonyms: N-Acetyl GABA
4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .
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1
1 Cited Publications
Cat. No.: HY-Y0068
CAS No.: 2018-61-3
Synonyms: N-Acetylphenylalanine
N-Acetyl-L-phenylalanine (N-Acetylphenylalanine) is a principal acylamino acid. N-Acetyl-L-phenylalanine can be synthesized from L-phenylalanine and acetyl-CoA. N-Acetyl-L-phenylalanine can be used in kidney research .
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1
1 Cited Publications
Cat. No.: HY-W014130
CAS No.: 155-84-0
Synonyms: Ac-Arg-OH
N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population. N-Acetyl-L-arginine shows synergistic activity with glycine buffer. N-Acetyl-L-arginine suppresses the aggregation of intravenous immunoglobulins with a minimum decrease in transition temperature. N-Acetyl-L-arginine dramatically reduces IL-1 expression in the presence of silicone oil. N-Acetyl-L-arginine also demonstrates colloidal stability .
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1
1 Cited Publications
Cat. No.: HY-B1442
CAS No.: 99-15-0
Synonyms: N-Acetyl-DL-leucine
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Acetylleucine (N-Acetyl-DL-leucine), orally active compound, can be used for the research of acute vestibular vertigo, cerebellar ataxia and nystagmus .
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1
1 Cited Publications
Cat. No.: HY-17490
CAS No.: 33996-33-7
Synonyms: N-Acetyl-L-hydroxyproline
Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis .
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