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Results for "

NDP

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Natural
Products

3

Recombinant Proteins

6

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107139
    JNJ-10229570

    		Melanocortin Receptor Endocrinology
    JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.
    JNJ-10229570
  • HY-113206
    D-Sedoheptulose 7-phosphate

    		Endogenous Metabolite Metabolic Disease
    D-Sedoheptulose 7-phosphate is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose 7-phosphate can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds .
    D-Sedoheptulose 7-phosphate
  • HY-113206A
    D-Sedoheptulose-7-phosphate barium
    1 Publications Verification

    		 Endogenous Metabolite Metabolic Disease
    D-Sedoheptulose-7-phosphate barium is a common precursor for the heptoses of septacidin (group III) and hygromycin B (group IV). D-Sedoheptulose-7-phosphate barium can be converted to NDP-heptoses through similar biosynthetic pathways in those compounds .
    D-Sedoheptulose-7-phosphate barium
  • HY-E70122
    Uridylate kinase

    		Others Others
    Uridylate kinase is a member of the nucleoside mono-phosphate (NMP) kinase family and catalyzes the reaction ATP+NMP ADP+NDP with moderate specificity for UMP .
    Uridylate kinase
  • HY-P2881
    Nucleoside diphosphate kinase

    Nucleoside 5′-diphosphate kinase

    		 Biochemical Assay Reagents Cancer
    Nucleoside diphosphate kinase (Nucleoside 5′-diphosphate kinase) belongs to the family of structurally and functionally conserved NDPK (Nucleotide diphosphate kinase) enzymes. Nucleoside diphosphate kinase catalyzes the reversible transfer of γ-phosphates between nucleoside di-(NDP) and triphosphates (NTP) through ping-pong bi-bi reaction kinetics. Nucleoside diphosphate kinase is the essential housekeeping proteins that produces CTP (cytidine triphosphate) for lipid syntheses, UTP (Uridine triphosphate) for polysaccharide syntheses, and GTP (guanosine triphosphate) for protein syntheses, signal transduction, and microtubules polymerization .
    Nucleoside diphosphate kinase
  • HY-RS09113
    NDP Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    NDP Human Pre-designed siRNA Set A contains three designed siRNAs for NDP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NDP Human Pre-designed siRNA Set A
    NDP Human Pre-designed siRNA Set A
  • HY-RS19302
    Ndp Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ndp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ndp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ndp Mouse Pre-designed siRNA Set A
    Ndp Mouse Pre-designed siRNA Set A
  • HY-121183
    Aprikalim

    RP 52891

    		 Potassium Channel Cardiovascular Disease
    Aprikalim (RP 52891), a potassium channel opener (KCO), activates ATP-sensitive K+ (KATP) channels in guinea pig ventricular myocytes. Using patch-clamp techniques, it was found that aprikalim enhances KATP channel activity more effectively in Mg-NDP solution compared to standard solutions. In Mg-NDP solution, aprikalim reduced the sensitivity of KATP channels to ATP, increasing the concentration of ATP required to inhibit channel activity by half (K1) from 56 μM to 180 μM. However, this effect diminished over time. Aprikalim's ability to activate KATP channels in Mg-NDP solution suggests potential therapeutic implications in modulating cardiac excitability and may relate to changes in channel protein enzymatic activity under experimental conditions .
    Aprikalim
  • HY-RS25793
    Ndp Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ndp Rat Pre-designed siRNA Set A contains three designed siRNAs for Ndp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ndp Rat Pre-designed siRNA Set A
    Ndp Rat Pre-designed siRNA Set A
  • HY-107139R
    JNJ-10229570 (Standard)

    		Reference Standards Melanocortin Receptor Endocrinology
    JNJ-10229570 (Standard) is the analytical standard of JNJ-10229570 (HY-107139). This product is intended for research and analytical applications. JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.
    JNJ-10229570 (Standard)

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