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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
NOS1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "NOS1" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-18732
CAS No.: 17035-90-4
Synonyms: Tilarginine; Methylarginine
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L-NMMA (Tilarginine) is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production . L-NMMA alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA is applicable to research related to nociception, bone cancer pain, and myopia [1] .
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8 Cited Publications
Cat. No.: HY-N6607
CAS No.: 13220-57-0
1
1 Cited Publications
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ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers [1].
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Cat. No.: HY-RS09433
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NOS1 Human Pre-designed siRNA Set A contains three designed siRNAs for NOS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NOS1-IN-1 is a selective and cell-permeable nNOS inhibitor with a Ki of 120 nM. NOS1-IN-1 exhibits 2617-fold and 325-fold selectivity over eNOS (Ki=39 μM) and iNOS (Ki=325 μM) , respectively [1]. NOS1-IN-1 can be used for the research of neurological disease, including cerebral palsy (CP) .
Cat. No.: HY-RS09434
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Nos1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nos1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N6607R
CAS No.: 13220-57-0
Cat. No.: HY-RS09435
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Nos1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nos1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09436
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NOS1AP Human Pre-designed siRNA Set A contains three designed siRNAs for NOS1AP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19265
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Nos1ap Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nos1ap gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25754
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Nos1ap Rat Pre-designed siRNA Set A contains three designed siRNAs for Nos1ap gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09021
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NANOS1 Human Pre-designed siRNA Set A contains three designed siRNAs for NANOS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-12117
CAS No.: 150403-89-7
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L-NIL hydrochloride is an inducible NO synthase inhibitor, with an IC50 of 3.3 μM for mouse inducible NOS .
Cat. No.: HY-124996
Purity: 98.96%
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(Rac)-ZLc-002, an inhibitor of nNOS interaction with nitric oxide synthase 1 adaptor protein (NOS1AP), suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with Paclitaxel (HY-B0015) to reduce tumor cell viability [1] .
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S-Isopropylisothiourea hydrobromide (S-isopropyl ITU; IPTU) is a blood-brain barrier (BBB) penetrant NOS inhibitor with IC50 values of 0.66, 0.75 and 0.29 μM against mouse spinal cord, cerebellar, bovine aortic and porcine endothelial cell NOS. S-Isopropylisothiourea exhibits a significant blood pressure-raising effect without damaging the perfusion of vital organs and can also inhibit the late-phase pain response induced by formalin. S-Isopropylisothiourea hydrobromide is used in the researchs for hemorrhagic shock and pain response based on NOS .
Cat. No.: HY-107720R
CAS No.: 866914-87-6
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ARL 17477 (Standard) is the analytical standard of ARL 17477 (HY-107720). This product is intended for research and analytical applications. ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers [1].
Cat. No.: HY-RS21891
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Nanos1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nanos1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
