10234 Results for "

Natural Products,Emodin derivative

" in MedChemExpress (MCE) Product Catalog:
Products (10234)

10234 Results for "Natural Products,Emodin derivative" in MCE Product Catalog:

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229
229 Cited Publications
Cat. No.: HY-18085A
CAS No.: 849061-97-8
Quercetin hydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
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224
224 Cited Publications
Cat. No.: HY-N0146
CAS No.: 6151-25-3
Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively .
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167
167 Cited Publications
Cat. No.: HY-17031
CAS No.: 182410-00-0
Synonyms: Sulfobutylether-β-Cyclodextrin
SBE-β-CD is a sulfobutylether β-cyclodextrin derivative used as an excipient or a formulating agent to increase the solubility of poorly soluble agents .
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150
150 Cited Publications
Cat. No.: HY-14649
CAS No.: 302-79-4
Purity:  99.81%
Synonyms: Vitamin A acid; all-trans-Retinoic acid; ATRA
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
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138
138 Cited Publications
Cat. No.: HY-N0005
CAS No.: 458-37-7
Synonyms: Diferuloylmethane; Natural Yellow 3; Turmeric yellow
Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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98
98 Cited Publications
Cat. No.: HY-112675
CAS No.: 3133-16-2
Purity:  99.92%
Synonyms: 4-OI
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 .
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98
98 Cited Publications
Cat. No.: HY-17393
CAS No.: 41575-94-4
Synonyms: NSC 241240
Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.
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83
83 Cited Publications
Cat. No.: HY-18258
CAS No.: 633-65-8
Synonyms: Natural Yellow 18 chloride
Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties .
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80
80 Cited Publications
Cat. No.: HY-N0716B
CAS No.: 633-66-9
Synonyms: Natural Yellow 18 sulfate
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .
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77
77 Cited Publications
Cat. No.: HY-17577
CAS No.: 68030-18-2
Synonyms: Natural Yellow 18 chloride hydrate
Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties .
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61
61 Cited Publications
Cat. No.: HY-14650
CAS No.: 53-43-0
Purity:  99.93%
Synonyms: Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone
DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
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54
54 Cited Publications
Cat. No.: HY-N0716A
CAS No.: 316-41-6
Synonyms: Natural Yellow 18 hemisulfate
Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
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51
51 Cited Publications
Cat. No.: HY-N1201
CAS No.: 520-36-5
Synonyms: 4',5,7-Trihydroxyflavone; Apigenol; C.I. Natural Yellow 1
Apigenin (4',5,7-Trihydroxyflavone) is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
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48
48 Cited Publications
Cat. No.: HY-D1374
CAS No.: 1144107-82-3
Sulfo-Cy5 carboxylic acid potassium is a Cy5 derivative that can be used for chemical synthesis. Cy5 is a red fluorescent label dye for imaging (Ex/Em=642/670 nm) .
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47
47 Cited Publications
Cat. No.: HY-N0174
CAS No.: 35825-57-1
Synonyms: Cryptotanshinon; Tanshinone c
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC50 of 4.6 μM.
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44
44 Cited Publications
Cat. No.: HY-N1428
CAS No.: 77-92-9
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
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38
38 Cited Publications
Cat. No.: HY-13624
CAS No.: 56420-45-2
Synonyms: 4'-Epidoxorubicin
Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase . Epirubicin inhibits DNA and RNA synthesis. Epirubicin is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity .
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38
38 Cited Publications
Cat. No.: HY-13624A
CAS No.: 56390-09-1
Purity:  99.15%
Synonyms: 4'-Epidoxorubicin hydrochloride
Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase . Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity .
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38
38 Cited Publications
Cat. No.: HY-10529
CAS No.: 472-15-1
Purity:  99.06%
Synonyms: Lupatic acid; Betulic acid
Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties . Betulinic acid can cross the blood-brain barrier .
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