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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
120 Results for "
P-388
" in MedChemExpress (MCE) Product Catalog:
Products (120)
120 Results for "P-388" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-N3308
CAS No.: 32383-76-9
Target:
3
Category:
Labiatae Terpenoids Ulex europaeus L. Diterpenoids Plants Disease Research Fields Oxytropis falcata Bunge Cancer
Target:
2
2 Cited Publications
Synonyms: 5,10-Methylenetetrafolate; ANX-510 free acid
Target:
1
N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells .
Cat. No.: HY-18351
CAS No.: 915303-09-2
Synonyms: LMP-400; NSC-724998
Target:
Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Cat. No.: HY-18351A
CAS No.: 1228035-68-4
Synonyms: LMP-400 hydrochloride; NSC-724998 hydrochloride
Target:
Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis .
Cat. No.: HY-P3116
CAS No.: 173046-02-1
Cat. No.: HY-108603
CAS No.: 87745-28-6
Synonyms: (+)-Bryostatin 2
Bryostatin 2 ((+)-Bryostatin 2) is a 20-membered ring lactone that can be found in Bryozoan Eugufa neritina L. Bryostatin 2 has the potential for the research of P-388 lymphocytic
leukemia .
Cat. No.: HY-N6955
CAS No.: 757202-08-7
Category:
Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Cancer
Target:
Cat. No.: HY-N10208
CAS No.: 1216840-17-3
Category:
Natural Products Microorganisms Marine natural products Disease Research Fields Marine microorganism Cancer
Target:
Cat. No.: HY-12458
CAS No.: 118292-36-7
Target:
Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml .
Cat. No.: HY-N1631
CAS No.: 53600-24-1
Synonyms: 1-Hydroxyrutaecarpine
Target:
Research Areas:
1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity .
Cat. No.: HY-125037
CAS No.: 1190948-58-3
Category:
Target:
Cat. No.: HY-N1655
CAS No.: 873999-88-3
Category:
Flavonoids Phenols Polyphenols Selaginella delicatula (Desv.) Alston Selaginellaceae Plants Disease Research Fields Biflavones Cancer
Target:
Target:
1-Hydroxyguanidine sulfate is an antitumor agent that inhibits mast cell P815, leukaemia P388, leukaemia L1210 and carcinosarcoma Walker 256 cells growth. 1-Hydroxyguanidine sulfate also has antiviral activity .
Synonyms: 2-Aminoadamantane-2-carboxylic acid
Target:
Research Areas:
Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
Cat. No.: HY-14769A
CAS No.: 133978-75-3
Synonyms: 5,10-Methylenetetrafolate calcium; ANX-510
Target:
Research Areas:
Folitixorin calcium (5,10-Methylenetetrafolate calcium; ANX-510) is a reduced form of Folic acid (HY-16637) and a cofactor of thymidylate synthase . Folitixorin calcium acts as an essential cofactor to promote the formation of a tight ternary complex between thymidylate synthase and FdUMP, thereby enhancing the inhibitory effect of FdUMP on thymidylate synthase. Folitixorin calcium in combination with 5-fluorouracil and αVEGF reduces tumor volume in colorectal tumor models of nude mice. Folitixorin calcium is used in related research on Yoshida sarcoma, P-388 leukemia, and colorectal cancer .
Cat. No.: HY-N15640
CAS No.: 62311-75-5
Synonyms: (-)-Filiformin
Target:
Cat. No.: HY-136514
CAS No.: 83166-17-0
Target:
Research Areas:
Tampramine (47), a phenothiazine, could reverse multidrug resistance, with ED50 values of 60 μM (P388 cells) and 60 μM (P388/ADR cells), respectively .
Cat. No.: HY-N2835
CAS No.: 62394-00-7
Category:
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
