27 Results for "

PH2

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "PH2" in MCE Product Catalog:

10
10 Publications Verification
Cat. No.: HY-123937
CAS No.: 2139287-33-3
Purity:  99.16%
Research Areas:  

Infection Cancer

THAL-SNS-032 is a selective CDK9 PROTAC degrader. THAL-SNS-032 recruits CRBN to form a ternary complex with CDK9, thereby triggering ubiquitination and proteasomal degradation of CDK9. THAL-SNS-032 also induces the degradation of CDK1, CDK2 and CDK7. THAL-SNS-032 elevates pH2AX levels, reduces MCL1s expression, and activates caspase-3. THAL-SNS-032 induces cancer cell apoptosis, regulates transcription, and inhibits the replication of human cytomegalovirus (CMV) and SARS-CoV-2. THAL-SNS-032 can be used in research related to breast cancer, leukemia, cytomegalovirus infection and SARS-CoV-2 infection [2] .
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3
3 Cited Publications
Cat. No.: HY-N0316
CAS No.: 55481-88-4
Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway [2] .
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2
2 Cited Publications
Cat. No.: HY-158082C
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 70000
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
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2
2 Cited Publications
Cat. No.: HY-158082
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 4000
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching [2] .
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Cat. No.: HY-158082A
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 20000
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching [2] .
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Cat. No.: HY-113377
CAS No.: 28305-26-2
L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2 [2].
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Cat. No.: HY-128369
CAS No.: 587-98-4
Purity:  ≥85.0%
Synonyms: Metanil Yellow
Acid Yellow 36 (Metanil Yellow) is an azo dye and a pH indicator. Acid Yellow 36 changes its color from red at pH 1.2 to yellow at pH 2.3. Acid Yellow 36 is used in the leather, paper and textile industries. Acid Yellow 36 acts as a bifunctional inducer of specific isozymes of P-450 and cytosolic enzymes [2] .
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Cat. No.: HY-158082D
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 150000
TRITC-dextran, MW 150000 (Tetramethyl rhodamine isothiocyanate glucan, MW 150000) is a fluorescent dye, with the molecular weight of 150 kD. TRITC-dextran, MW 150000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 150000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 150000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching [2] .
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Cat. No.: HY-D0812
CAS No.: 125-31-5
Xylenol Blue is a sulfonephthalein dye. It exhibits observable color changes in response to variations in pH. Xylenol Blue undergoes two distinct color transitions across two specific pH ranges: an acidic range and an alkaline range. In a neutral solution, Xylenol Blue appears yellow (at pH 8); in a strongly acidic medium, its color shifts to red (at pH 2.8); and in an alkaline medium, the yellow hue transitions to blue (at pH 9.6) .
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Cat. No.: HY-158082E
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 500000
TRITC-dextran, MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye, with the molecular weight of 500 kD. TRITC-dextran, MW 500000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 500000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 500000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching [2] .
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Cat. No.: HY-158082H
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 2000000
TRITC-dextran, MW 2000000 (Tetramethyl rhodamine isothiocyanate glucan, MW 2000000) is a fluorescent dye, with the molecular weight of 2000 kD. TRITC-dextran, MW 2000000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 2000000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 2000000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching [2] .
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Cat. No.: HY-113377A
CAS No.: 146298-95-5
Purity:  ≥99.0%
L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2 [2].
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Cat. No.: HY-D0015
CAS No.: 1733-12-6
Cresol red, 97% is an acidic phenolsulfonphthalein triphenylmethane dye. Cresol red, 97% generates reactive oxygen species and singlet oxygen under ultrasonic irradiation, interacts with bovine serum albumin, alters the structure of bovine serum albumin, and oxidizes the fluorescent amino acid residues of bovine serum albumin. Cresol red, 97% can be decolorized and biodegraded by *Absidia spinosa* M15, producing phenylacetic acid and benzoic acid metabolites. Cresol red, 97% serves as a pH indicator (orange at pH 1.8-yellow at pH 2.0, yellow at pH 7.0-purple at pH 8.8). Cresol red, 97% can be used to indicate pH, temperature and salinity [2].
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Cat. No.: HY-N0316R
CAS No.: 55481-88-4
Mollugin (Standard) is the analytical standard of Mollugin. This product is intended for research and analytical applications. Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway [2] .
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Cat. No.: HY-P88708
Synonyms: GLXR; GLYD; PH2

Host:  

Mouse

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P88708A
Synonyms: GLXR; GLYD; PH2

Host:  

Mouse

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-RS05790
Research Areas:  

Others

GRHPR Human Pre-designed siRNA Set A contains three designed siRNAs for GRHPR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS10410
Research Areas:  

Others

PHC2 Human Pre-designed siRNA Set A contains three designed siRNAs for PHC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-149036
PAA5 is a methide carbon-centered polynuclear Au(I) cluster. PAA5 can release Au(I) causing Pro-oxidant response and accelerated ferroptosis. PAA5 increases the expression of pH2AX in a time-dependent manner. PAA5 has anticancer activity .
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Cat. No.: HY-162985
Target:  

CDK

Research Areas:  

Cancer

JHD205 is a CDK4/6 inhibitor that induces apoptosis and DNA damage. JHD205 inhibits DNA repair by upregulating Caspase3 and p-H2AX. JHD205 has superior potency to Abemaciclib (HY-16297A) in a xenograft chick embryo breast cancer model. .
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