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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
PROS1
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "PROS1" in MCE Product Catalog:
2
2 Cited Publications
Research Areas:
BTZO-1, a chemical probe, binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro [1].
1
1 Cited Publications
X77 is a potent non-covalent inhibitor of the main protease of SARS-CoV-2 (SARS-CoV-2 M pro) . X77 binds to SARS-CoV-2 M pro with a Kd value of 0.057 μM .
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Cat. No.: HY-D0918
CAS No.: 152068-09-2
Cat. No.: HY-RS11202
Target:
Research Areas:
PROS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PROS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18835
Target:
Research Areas:
Pros1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pros1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P4388
CAS No.: 167698-69-3
Cat. No.: HY-RS25327
Target:
Research Areas:
Pros1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pros1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
(Rac)-X77?is a racemate of X77. X77 is a potent non-covalent inhibitor of the main protease of SARS-CoV-2 (SARS-CoV-2 M pro) . X77 binds to SARS-CoV-2 M pro with a Kd value of 0.057 μM .
Cat. No.: HY-168050
Target:
Research Areas:
SGC-NSP2PRO-1 is a potent irreversible covalent inhibitor of Chikungunya (CHIKV) nsP2 cysteine protease with an IC50 value of 60 nM. SGC-NSP2PRO-1 demonstrates potent antialphavirus activity, inhibiting CHIKV and VEEV replication with EC50 = 0.01 and 0.3 µM, respectively [1].
Cat. No.: HY-174352
CAS No.: 2412120-47-7
Research Areas:
TERT ligand-1 is a PROTAC target protein ligand that can be used to synthesize the PROTAC NU-PRO-1 (HY-174351). NU-PRO-1 induces TERT degradation in cancer cells [1].
Cat. No.: HY-P704850
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Vitamin K-dependent protein S; PROS1; PROS
Cat. No.: HY-157145
CAS No.: 78471-90-6
SARS-CoV-2-IN-69 (Compound 7E) is a non-covalent SARS-CoV-2 inhibitor with an EC50 value of 7.4 μM. SARS-CoV-2-IN-69 is a potent inhibitor of SARS-CoV-2 main protease (M pro) and a non-covalent inhibitor of papain (PL pro) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
