41 Results for "

Pro-Gly-Pro

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "Pro-Gly-Pro" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P4846
CAS No.: 292171-04-1
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .
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2
2 Cited Publications
Cat. No.: HY-P1349
CAS No.: 202801-92-1
Synonyms: Rat orexin B; Orexin B (mouse)
Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.
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1
1 Cited Publications
Cat. No.: HY-P4860
CAS No.: 1802086-30-1
Target:  

Akt Gli JNK PKA

Research Areas:  

Metabolic Disease

Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway .
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1
1 Cited Publications
Cat. No.: HY-P1146
CAS No.: 80714-61-0
Semax is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu 2+. Semax is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax has immunomodulatory, nootropic and neuroprotective activities. Semax can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .
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1
1 Cited Publications
Cat. No.: HY-P1146A
CAS No.: 2828433-33-4
Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide and can form stable complexes with Cu 2+. Semax acetate is a synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10). Semax acetate has immunomodulatory, nootropic and neuroprotective activities. Semax acetate can be used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia .
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Cat. No.: HY-P4486
CAS No.: 7561-51-5
Synonyms: Pro-Gly-Pro
Target:  

Drug Derivative

Research Areas:  

Others

H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .
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Cat. No.: HY-105042
CAS No.: 129954-34-3
Synonyms: Selanc; TP-7
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Selank (Selanc; TP-7) is a GABAA receptor modulator with anxiolytic activity. Selank allosterically modulates the specific binding of GABA to GABAA receptors and alters the affinity of endogenous ligands for these receptors. Selank reduces elevated anxiety levels, attenuates stress-induced exacerbation of anxiety, and produces a synergistic anxiolytic effect with diazepam. Selank can be used in the research of anxiety disorders .
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Cat. No.: HY-P0179
CAS No.: 72122-62-4
Synonyms: β-Casomorphin-7 (bovine); Bovine β-casomorphin-7
Target:  

Opioid Receptor

β-Casomorphin, bovine (β-Casomorphin-7 (bovine) ) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay .
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Cat. No.: HY-P10904
CAS No.: 51486-77-2
Synonyms: ST-100
Target:  

Collagen

Research Areas:  

Others

Vezocolmitide (ST-100) is a collagen mimetic peptide. Vezocolmitide can rapidly repair damaged collagen triple helix structures, thereby quickly reversing damage to the ocular surface and extracellular matrix, and restoring corneal nerve function while repairing the epithelium. Vezocolmitide can be used for research of dry eye disease (DED) .
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Cat. No.: HY-105042A
Purity:  99.90%
Synonyms: Selanc diacetate; TP-7 diacetate
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Selank diacetate (Selanc diacetate; TP-7 diacetate) is a GABAA receptor modulator with anxiolytic activity. Selank diacetate allosterically modulates the specific binding of GABA to GABAA receptors and alters the affinity of endogenous ligands for these receptors. Selank diacetate reduces elevated anxiety levels, attenuates stress-induced exacerbation of anxiety, and produces a synergistic anxiolytic effect with diazepam. Selank diacetate can be used in the research of anxiety disorders .
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Cat. No.: HY-P11087
CAS No.: 134335-45-8
Target:  

Collagen

Research Areas:  

Others

P15 is a collagen mimetic peptide with the sequence of GTPGPQGIAGQRGVV. P15 can mimic the cell-binding domain of human type I collagen. P15 is capable of promoting the adhesion, proliferation, and differentiation of osteoblasts. Biomaterials modified with P15 can be used in research related to bone regeneration .
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Cat. No.: HY-P1064
CAS No.: 252642-12-9
Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC50=8.61). Apelin-36 has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-P5731
Target:  

Bacterial

Research Areas:  

Infection

Bac7(1-35) is a proline-rich antimicrobial peptide. Bac7(1-35) efficiently binds to different regions of prokaryote ribosomes, leading to the inhibition of protein synthesis. Bac7(1-35) demonstrates in vitro activity against P. aeruginosa strains .
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Cat. No.: HY-P3588
CAS No.: 2920938-90-3
N-Acetyl semax amidate is a synthetic heptapeptide with nootropic and neuroprotective activities, derived from Met-Glu-His-Phe-Pro-Gly-Pro via N-terminal acetylation and C-terminal amidation modifications. N-Acetyl semax amidate exerts neuroprotective effects by upregulating the expression of BDNF and NGF, inhibiting neuronal apoptosis, alleviating oxidative stress, and reducing glutamate excitotoxicity. N-Acetyl semax amidate can be used in relevant research on central nervous system diseases such as ischemic stroke, cognitive impairment, and neurodegenerative diseases .
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Cat. No.: HY-P3395
CAS No.: 197151-46-5
Synonyms: Human chromogranin A 352–372
Target:  

nAChR

Catestatin human, a catecholamine release-inhibitory peptide, is a pleiotropic peptide involved in cardiovascular protection with its antihypertensive and angiogenic effects. Catestatin human can be used in the study of inflammatory diseases .
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Cat. No.: HY-P1064A
Apelin-36(human) TFA is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) TFA shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC550=8.61). Apelin-36(human) TFA has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-P11281A
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

GYGGGP(GPP)5GFOGER(GPP)5GPC TFA is a type I collagen mimic that can bind to integrins and modify hydrogels .
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Cat. No.: HY-P11281
CAS No.: 3063714-39-3
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

GYGGGP(GPP)5GFOGER(GPP)5GPC is a type I collagen mimic that can bind to integrins and modify hydrogels .
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Cat. No.: HY-P1067
CAS No.: 117830-79-2
Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.
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Cat. No.: HY-P5731A
Target:  

Bacterial

Research Areas:  

Infection

Bac7(1-35) acetate is a proline-rich antimicrobial peptide. Bac7(1-35) acetate efficiently binds to different regions of prokaryote ribosomes, leading to the inhibition of protein synthesis. Bac7(1-35) acetate demonstrates in vitro activity against P. aeruginosa strains .
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