28 Results for "

Ptk7

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "Ptk7" in MCE Product Catalog:

  • Targets Recommended:
1
1 Cited Publications
製品番号: HY-P78619
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
Rat
Source:  
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1
1 Cited Publications
製品番号: HY-P78761
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
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製品番号: HY-P99829
CAS 番号: 1869937-48-3
別名: PF-06647020; ABBV-647; h6M24-vc0101
Cofetuzumab pelidotin (PF-06647020) is a PTK7-targeting ADC comprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to an auristatin microtubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc)-based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with an EC50 of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research .
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製品番号: HY-P99828
CAS 番号: 1869928-62-0
別名: PF-06523435; hu24

Target:  

ADC Antibodies RET PERK ROR

研究分野:  

Cancer

Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7. The expression system of Cofetuzumab is typically CHO (Chinese hamster ovary) cells. Cofetuzumab downregulates PTK7 expression, modulates its downstream signaling pathways, and inhibits tumor sphere formation of ovarian cancer cells. Cofetuzumab can be used to synthesize the ADC molecule Cofetuzumab pelidotin (HY-P99829). Cofetuzumab is applicable to the research of tumors such as ovarian cancer .
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製品番号: HY-160488
CAS 番号: 906147-24-8
Target:  

β-catenin

研究分野:  

Cancer

PTK7/β-catenin-IN-1 (compound 01065) is a potent PTK7/β-catenin inhibitor with an IC50 of 8.9 μM and 56.5 μM for PTK7/β-catenin and p53/MDM2, respectively. PTK7/β-catenin-IN-1 has the potential for cancer research .
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製品番号: HY-RS11404
研究分野:  

Others

PTK7 Human Pre-designed siRNA Set A contains three designed siRNAs for PTK7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS17543
研究分野:  

Others

Ptk7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptk7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS24001
研究分野:  

Others

Ptk7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptk7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Sgc8c-M
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Sgc8c-M
製品番号: HY-177571
別名: Sgc8c-VcMMAE
Sgc8c-M is a PTK7-targeted aptamer-drug conjugate (ApDC). Sgc8c-M is composed of the classic PTK7-specific aptamer Sgc8c, a cathepsin B (CTSB)-cleavable valine-citrulline (VC)-based linker, and the potent antimitotic agent Monomethyl auristatin E (MMAE) (HY-15162) as the payload. Sgc8c-M inhibits the growth of PTK7-overexpressing cancer cells. Sgc8c-M can be used for the study of PTK7-expressing advanced solid tumors .
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製品番号: HY-160493
CAS 番号: 1219439-82-3
Target:  

Wnt β-catenin

研究分野:  

Cancer

PTK7/β-catenin-IN-6 (Compound 03653) is an inhibitor for PTK7/β-catenin interaction, which inhibits the Wnt signaling pathway, and exhibits an anticancer activity against colorectal cancer (CRC) .
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sgc8c aptamer sodium
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DNA, 5'-ATCTAACTGCTGCGCCGCCGGGAAAATACTGTACGGTTAGA-3', sodium salt
製品番号: HY-160065
sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. sgc8c aptamer sodium can precisely bring the nanotags connected to it to the surface of cells expressing PTK-7, thus achieving specific recognition and labeling of target cells .
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製品番号: HY-160489
CAS 番号: 902434-29-1
Target:  

β-catenin Wnt

研究分野:  

Cancer

PTK7/β-catenin-IN-2 (compound 04967) is an inhibitor of PTK7/β-catenin. It inhibits the binding of PTK7 to β-catenin (IC50: 5.6 μM), thereby inhibiting the signaling of the Wnt/β-catenin pathway. PTK7/β-catenin-IN-2 targets cell growth dependent on the Wnt signaling pathway and has anticancer properties. PTK7/β-catenin-IN-2 also showed inhibitory potency against p53 and MDM2 binding with an IC50 of 157.1 μM .
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製品番号: HY-160065F
FAM-sgc8c aptamer sodium is a 5-FAM labeled sgc8c aptamer sodium (HY-160065). sgc8c aptamer sodium is an aptamer that specifically targets the human protein tyrosine kinase PTK-7, which is mainly expressed on cervical cancer HeLa cells. Binding of FAM-sgc8c aptamer sodium to PTK-7 induces the assembly of nanotags on the cell surface, resulting in strong fluorescence and SERS signals .
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製品番号: HY-P84534
別名: CCK4; Ptk7

Host:  

Mouse

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human

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製品番号: HY-P703966
純度:  ≥ 95%, as determined by Bis-Tris PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
Source:  
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製品番号: HY-P705077
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
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製品番号: HY-P78398
純度:  ≥ 95%, as determined by Bis-Tris PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
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製品番号: HY-P703970
純度:  ≥ 95%, as determined by Bis-Tris PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
Source:  
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製品番号: HY-P84534A
別名: CCK4; Ptk7

Host:  

Mouse

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human

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製品番号: HY-P703967
純度:  ≥ 95%, as determined by Bis-Tris PAGE.
別名: Ptk7; Ptk7 Protein Tyrosine Kinase 7; Protein Tyrosine Kinase 7 (Inactive); Tyrosine-Protein Kinase-Like 7; CCK4; CCK-4; Colon Carcinoma Kinase 4; Protein Tyrosine Kinase 7; Inactive Tyrosine-Protein Kinase 7; Protein-Tyrosine Kinase 7; Pseudo Tyrosine Ki
Species:  
Source:  
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