49 Results for "

RB1

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "RB1" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-N0039
CAS No.: 41753-43-9
Synonyms: Gypenoside III
Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na +, K +-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
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5
5 Cited Publications
Cat. No.: HY-N0904
CAS No.: 39262-14-1
Synonyms: Ginsenoside compound K; Ginsenoside K
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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1
1 Cited Publications
Cat. No.: HY-124962
CAS No.: 35922-06-6
Purity:  99.74%
Synonyms: (1R,2R)-B13
Target:  

iGluR

Research Areas:  

Neurological Disease Cancer

D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates NMDA receptor properties by enhancing endogenous production of ceramides. D-NMAPPD has anticancer effecs [1] .
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1
1 Cited Publications
Cat. No.: HY-N7678
CAS No.: 110261-98-8
Gypenoside LXXV, isolated from Gynostemma pentaphyllum, is one of the deglycosylated shapes of ginsenoside Rb1. Gypenoside LXXV significantly reduces cancer cell viability and displays an anti-cancer effect [1].
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Cat. No.: HY-159805
CAS No.: 2813260-27-2
Target:  

CDK

Research Areas:  

Cancer

CDK2-IN-31 is a CCNE1:CDK2 complex inhibitor with an IC50 of 0.13 μM. CDK2-IN-31 binds to a cryptic allosteric pocket at the CCNE1:CDK2 interface, inducing structural rearrangements of the CDK2 A-loop that disrupt the kinase's active conformation and interfere with substrate binding. CDK2-IN-31 inhibits phosphorylation of retinoblastoma protein 1 (RB1) in CCNE1-dependent ovarian cancer cells. CDK2-IN-31 impairs coenrichment of protein PRC1 with CCNE1-N112C:CDK2 complexes. CDK2-IN-31 can be used for the research of ovarian cancer [1].
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Cat. No.: HY-N0039R
CAS No.: 41753-43-9
Synonyms: Gypenoside III (Standard)
Ginsenoside Rb1 (Standard) is the analytical standard of Ginsenoside Rb1. This product is intended for research and analytical applications. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na +, K +-ATPase activity with an IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65 .
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Cat. No.: HY-W130610R
CAS No.: 124-26-5
Ginsenoside C-K (Standard) is the analytical standard of Ginsenoside C-K. This product is intended for research and analytical applications. Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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Cat. No.: HY-RS11713
Research Areas:  

Others

RB1 Human Pre-designed siRNA Set A contains three designed siRNAs for RB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0904R
CAS No.: 39262-14-1
Synonyms: Ginsenoside compound K(Standard); Ginsenoside K (Standard)
Ginsenoside C-K (Standard) is the analytical standard of Ginsenoside C-K. This product is intended for research and analytical applications. Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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Cat. No.: HY-RS16852
Research Areas:  

Others

Rb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N18382
CAS No.: 1268459-69-3
5,6-Didehydroginsenoside Rb1 is a dammarane-type saponin. 5,6-Didehydroginsenoside Rb1 can be isolated from the dried roots of Panax notoginseng [1].
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Cat. No.: HY-RS23293
Research Areas:  

Others

Rb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-176853
CAS No.: 3056083-14-5
Target:  

Wee1

Research Areas:  

Cancer

Myt1-IN-6 (Compound formula (1)) is a highly selective MYT1 kinase inhibitor. Myt1-IN-6 is promising for research of RB1-deficient cancers (e.g., triple-negative breast cancer) [1].
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Cat. No.: HY-N8030
CAS No.: 1012886-99-5
Pseudoginsenoside Rg3 (compound 8) is the product of ginsenoside Rb1 fermentation with Acremonium strictum AS 3.2058 [1].
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Cat. No.: HY-125848R
CAS No.: 62025-49-4
Ginsenoside F2 (Standard) is the analytical standard of Ginsenoside F2. This product is intended for research and analytical applications. Ginsenoside F2, a metabolite from Ginsenoside Rb1, induces apoptosis accompanied by protective autophagy in breast cancer stem cells [1].
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Cat. No.: HY-N2330R
CAS No.: 96829-59-3
Ginsenoside F2 (Standard) is the analytical standard of Ginsenoside F2. This product is intended for research and analytical applications. Ginsenoside F2, a metabolite from Ginsenoside Rb1, induces apoptosis accompanied by protective autophagy in breast cancer stem cells [1].
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Cat. No.: HY-N18029
CAS No.: 1679350-46-9
(24S)-Ginsenoside V is a monooxygenated derivative of Ginsenoside Rb1 (HY-N0039). (24S)-Ginsenoside V is the major circulating metabolite of Ginsenoside Rb1 in rat plasma. (24S)-Ginsenoside V appears in rat urine after intravenous and oral administration of Ginsenoside Rb1 to rats [1].
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Cat. No.: HY-N18026
CAS No.: 1395101-76-4
Ginsenoside V is a metabolite of Ginsenoside Rb1 (HY-N0039) [1].
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Cat. No.: HY-174640
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL12RB1 mRNA encodes the human interleukin 12 receptor subunit beta 1 (IL12RB1) protein, a type I transmembrane protein that belongs to the hemopoietin receptor superfamily.
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Cat. No.: HY-P703588
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Retinoblastoma-associated protein; p105-RB; p110-RB1; pRB; RB; pp110; RB1; Homo sapiens; Human; RB; Chromatin regulator; DNA-binding; Repressor
Species:  
Source:  
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