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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
RNR
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "RNR" in MCE Product Catalog:
5
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COH29 (RNR Inhibitor COH29) is a potent ribonucleotide reductase (RNR) inhibitor with anticancer activity. COH29 inhibits α and β subunit of RNR with IC50s of 16 μM.
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Monobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and exhibits good potential for vitiligo research. Monobenzone is a potent inhibitor of RNR (Ribonucleotide reductase) enzyme activity by targeting RRM2 (a regulatory small subunit M2 of RNR) protein, and thus has significant anti-leukemia efficacy in vitro and in vivo. Monobenzone inhibits acute myeloid leukemia (AML) cells proliferation and DNA synthesis, induces cell cycle arrest, and Apoptosis .
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2 Cited Publications
Cat. No.: HY-P700300
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ribonuclease R; RNR; RNase R; Protein VacB; vacB; yjeC
Cat. No.: HY-P10622
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Cat. No.: HY-164497
CAS No.: 605685-94-7
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NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. NSC 641396 is also a protein arginine N-methyltransferase 9 (PRMT9) inhibitor. NSC 641396 has antitumor activity .
Cat. No.: HY-RS09540
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NR2E3 Human Pre-designed siRNA Set A contains three designed siRNAs for NR2E3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11841
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Ren1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ren1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10621
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Cat. No.: HY-P10624
CAS No.: 1191923-95-1
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Cat. No.: HY-P10623
CAS No.: 1191923-94-0
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Cat. No.: HY-P10625
CAS No.: 368431-25-8
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Cat. No.: HY-RS16371
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RNR1 Human Pre-designed siRNA Set A contains three designed siRNAs for RNR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703481
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Mitochondrial-derived peptide MOTS-c; Mitochondrial open reading frame of the 12S rRNA-c; MT-RNR1; Homo sapiens; Human; DNA-binding
Cat. No.: HY-W791041
CAS No.: 116371-66-5
Synonyms: dFdCDP
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Gemcitabine 5'-diphosphate (dFdCDP) is a core active metabolic intermediate of Gemcitabine (HY-17026) and a potent ribonucleotide reductase (RNR) inhibitor. Gemcitabine 5'-diphosphate depletes deoxyribonucleotide pools, consumes deoxycytidine triphosphate and increases the phosphorylation level of gemcitabine. Gemcitabine 5'-diphosphate prolongs the intracellular retention duration of gemcitabine metabolites, enhances the nucleic acid incorporation of gemcitabine, and exerts anti-tumor/cytotoxic effects .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
