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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
55 Results for "
SCA
" in MedChemExpress (MCE) Product Catalog:
Products (55)
55 Results for "SCA" in MCE Product Catalog:
8
6
6
6 Cited Publications
Cat. No.: HY-P701341
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CASP3; Protein Yama; Caspase 3; Caspase-3; Apopain; CASP-3; CPP32; CPP-32; CPP32B; SCA-1; Caspase 3, Apoptosis-Related Cysteine Peptidase; Yama; Caspase 3, Apoptosis-Related Cysteine Protease; PARP Cleavage Protease; SREBP Cleavage Activity 1; Procaspase3
Species:
Human
Source:
E. coli
5
Target:
Research Areas:
Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
3
2
Target:
Research Areas:
Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels). Rimtuzalcap can be used for the research of movement disorders including essential tremor (ET) and spinocerebellar ataxia (SCA) .
2
2 Cited Publications
Cat. No.: HY-P71340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STUB1; CLL-Associated Antigen KW-8; STIP1 Homology And U-Box Containing Protein 1; Antigen NY-CO-7; CHIP; STIP1 Homology And U-Box Containing Protein 1, E3 Ubiquitin Protein Ligase; SDCCAG7; Heat Shock Protein A Binding Protein 2 (C-Terminal); HSPABP2; STIP1 Homology And U Box-Containing Protein 1; NY-CO-7; Serologically Defined Colon Cancer Antigen 7; UBOX1; RING-Type E3 Ubiquitin Transferase; Carboxy Terminus Of Hsp70-Interacting Protein; SCAR16; RING-Type E3 Ubiquitin Transferase CHIP; SCA48; E3 Ubiquitin-Protein Ligase CHIP
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P72874
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CASP3; Protein Yama; Caspase 3; Caspase-3; Apopain; CASP-3; CPP32; CPP-32; CPP32B; SCA-1; Caspase 3, Apoptosis-Related Cysteine Peptidase; Yama; Caspase 3, Apoptosis-Related Cysteine Protease; PARP Cleavage Protease; SREBP Cleavage Activity 1; Procaspase3
Species:
Human
Source:
E. coli
Target:
Research Areas:
NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias .
Cat. No.: HY-W982613
CAS No.: 142744-39-6
Target:
Research Areas:
SCA-40 is a vasodilator for bronchial smooth muscle. SCA-40 produces biphasic relaxation on bronchi with spontaneous tension, and the relaxation effect is not inhibited by various potassium channel blockers. SCA-40 can be used for research on bronchial conditions .
Cat. No.: HY-P60514S1
Target:
Research Areas:
Cat. No.: HY-109160R
CAS No.: 2167246-24-2
Synonyms: CAD-1883 (Standard)
Target:
Research Areas:
Rimtuzalcap (Standard) is the analytical standard of Rimtuzalcap (HY-109160). This product is intended for research and analytical applications. Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels). Rimtuzalcap can be used for the research of movement disorders including essential tremor (ET) and spinocerebellar ataxia (SCA) .
Cat. No.: HY-111200R
CAS No.: 887258-94-8
Synonyms: SCA 136 (Standard)
Target:
Research Areas:
Vabicaserin hydrochloride (Standard) is the analytical standard of Vabicaserin hydrochloride (HY-111200). This product is intended for research and analytical applications. Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
Cat. No.: HY-111200A
CAS No.: 887258-95-9
Synonyms: SCA-136 free base
Research Areas:
Vabicaserin is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.
Cat. No.: HY-P77365
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF14; Nystagmus 4, Congenital Autosomal Dominant; Fibroblast Growth Factor 14; Fibroblast Growth Factor; FHF4; SCA27A; SCA27; SCA27B; Fibroblast Growth Factor Homologous Factor 4; NYS4; FGF-14; FGF; FHF-4
Species:
Canine
Source:
E. coli
Cat. No.: HY-P700058AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF14; Nystagmus 4, Congenital Autosomal Dominant; Fibroblast Growth Factor 14; Fibroblast Growth Factor; FHF4; SCA27A; SCA27; SCA27B; Fibroblast Growth Factor Homologous Factor 4; NYS4; FGF-14; FGF; FHF-4
Species:
Human
Source:
E. coli
Cat. No.: HY-P75193
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF14; Nystagmus 4, Congenital Autosomal Dominant; Fibroblast Growth Factor 14; Fibroblast Growth Factor; FHF4; SCA27A; SCA27; SCA27B; Fibroblast Growth Factor Homologous Factor 4; NYS4; FGF-14; FGF; FHF-4
Species:
Human
Source:
E. coli
Cat. No.: HY-180155
CAS No.: 3105470-83-2
Target:
Keap1-Nrf2 Cholinesterase (ChE) Interleukin Related TNF Receptor Reactive Oxygen Species (ROS) Heme Oxygenase (HO) Quinone Reductase
Research Areas:
Keap1/Nrf2/ARE activator 2 is an activator of Keap1/Nrf2/ARE pathway and non-competitively inhibits AChE with an IC50 of 14.79 μM and a Ki of 1.35 μM. Keap1/Nrf2/ARE activator 2 promotes Nrf2 nuclear translocation, leading to antioxidant gene upregulation and enhanced cellular defense against oxidative stress. Keap1/Nrf2/ARE activator exhibits robust neuroprotection against both H2O2- and Scopolamine (SCA) (HY-N0296)-induced injury in PC12 cells. Keap1/Nrf2/ARE activator 2 ameliorates memory impairment and the neuro-inflammation associated with SCA-initiated cognitive dysfunction in a zebrafish model. Keap1/Nrf2/ARE activator 2 can be used for the research of Alzheimer's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
