32 Results for "

Streptococcus mutans

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "Streptococcus mutans" in MCE Product Catalog:

1
Rhein 8-O-β-D-Glucopyranoside
Rhein 8-O-β-D-Glucopyranoside
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1 Cited Publications
Cat. No.: HY-N6082
CAS No.: 34298-86-7
Category:  

Quinones Monophenols Rheum palmatum L. Polygonaceae Anthraquinones Metabolic Disease Phenols Plants Disease Research Fields

Target:  

Apoptosis Bcl-2 Family Caspase TGF-beta/Smad Bacterial

Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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2-Amino-5-chlorobenzophenone
2-Amino-5-chlorobenzophenone
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1 Cited Publications
Cat. No.: HY-77785
CAS No.: 719-59-5
Synonyms: 5-Chloro-2-aminobenzophenone
2-Amino-5-chlorobenzophenone (5-Chloro-2-aminobenzophenone) is a chemical intermediate. Derivatives of 2-Amino-5-chlorobenzophenone serve as skeletal muscle relaxants. 2-Amino-5-chlorobenzophenone acts as a starting material for the synthesis of anti-biofilm 2-amino-5-chlorobenzophenone Schiff bases. 2-Amino-5-chlorobenzophenone is applicable to research related to bacterial infections .\n
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D(+)-Raffinose pentahydrate
D(+)-Raffinose pentahydrate
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Cat. No.: HY-N1938
CAS No.: 17629-30-0
Synonyms: D-Raffinose pentahydrate
Category:  

other families Polysaccharides Other Diseases Plants Endogenous metabolite Disease Research Fields Saccharides

Target:  

Endogenous Metabolite Glucosylceramide Synthase (GCS) Bacterial Phosphodiesterase (PDE) Interleukin Related

D(+)-Raffinose pentahydrate is an orally active inhibitor of LecA (Kd = 32 μM) and GtfC. D(+)-Raffinose pentahydrate reduces cyclic diguanylate (c-di-GMP) by increased activity of a c-di-GMP specific phosphodiesterase. D(+)-Raffinose pentahydrate interferes with GTF function. D(+)-Raffinose pentahydrate decreases IL-4 and IL-5 mRNA. D(+)-Raffinose pentahydrate exhibits biofilm-inhibitory activity against Pseudomonas aeruginosa and Streptococcus mutans and inhibits allergic airway eosinophilia .
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D-Cysteine
D-Cysteine
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Cat. No.: HY-W018555
CAS No.: 921-01-7
Category:  

Human Gut Microbiota Metabolites Microorganisms Amino acids Endogenous metabolite

Target:  

Endogenous Metabolite Bacterial

D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day .
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Rebaudioside A
Rebaudioside A
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Cat. No.: HY-N0466
CAS No.: 58543-16-1
Category:  

Plants Compositae Endogenous metabolite Sweeteners Food Research Trifolium hybridum L. Terpenoids Other Diseases Diterpenoids Disease Research Fields

Target:  

Glycosidase HMG-CoA Reductase (HMGCR) Fatty Acid Synthase (FASN) LDLR

Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC50 value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity .
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Ceanothic acid
Ceanothic acid
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Cat. No.: HY-N3558
CAS No.: 21302-79-4
Synonyms: Emmolic acid
Category:  

Other Terpenoids other families Terpenoids Plants Disease Research Fields Cancer

Target:  

Bacterial

Ceanothic acid (Emmolic acid) is an orally active pentacyclic triterpenoid. Ceanothic acid inhibits the growth of various oral bacteria, including Streptococcus mutans, Actinomyces viscosus, Porphyromonas gingivalis, and Prevotella intermedia. Ceanothic acid scavenges DPPH and H2O2 free radicals. Ceanothic acid inhibits acetic acid (HY-Y0319)-induced writhing response, xylene-induced ear swelling, and carrageenan-induced paw swelling in mice. Ceanothic acid can be used in research related to oral bacterial infections, ovarian cancer, liver cancer, and liver injury .
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Guaijaverin
Guaijaverin
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Cat. No.: HY-N2224
CAS No.: 22255-13-6
Category:  

Infection Flavonols Flavonoids Rosaceae Phenols Polyphenols Plants Disease Research Fields Eriobotrya japonica (Thunb.) Lindl.

Target:  

Bacterial

Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .
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Kuwanon G
Kuwanon G
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Cat. No.: HY-N4247
CAS No.: 75629-19-5
Category:  

Infection Flavonoids Flavones Phenols Polyphenols Plants Moraceae Disease Research Fields Morus alba Linn.

Target:  

Bombesin Receptor Bacterial Apoptosis Reactive Oxygen Species (ROS) PI3K Akt GSK-3 MMP mTOR NF-κB LXR

Kuwanon G is a flavonoid compound and an antagonist of the bombesin receptor. Kuwanon G has multiple activities such as bactericidal, anti-tumor, anti-inflammatory, antioxidant, anti-atherosclerotic, and neuroprotective effects. Kuwanon G exhibits strong antibacterial activity against oral pathogens, especially cariogenic bacteria and periodontal pathogens. Kuwanon G can induce apoptosis and inhibit proliferation, migration, and invasion of tumor cells. Kuwanon G can be used in the research of diseases such as gastric cancer and atherosclerosis .
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5,6-O-Isopropylidene-L-ascorbic acid
5,6-O-Isopropylidene-L-ascorbic acid
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Cat. No.: HY-W014141
CAS No.: 15042-01-0
Synonyms: L-Ascorbic acid 5,6-acetonide
5,6-O-Isopropylidene-L-ascorbic acid (L-Ascorbic acid 5,6-acetonide) is an organic compound and a derivative of L-ascorbic acid (vitamin C). 5,6-O-Isopropylidene-L-ascorbic acid inhibits biofilm formation by pathogenic bacteria. 5,6-O-Isopropylidene-L-ascorbic acid is applicable to studies related to bacterial infections .
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Rhodomyrtone
Rhodomyrtone
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Cat. No.: HY-N13668
CAS No.: 468757-69-9
Category:  

Myrtaceae Phenols Polyphenols Rhodomyrtus tomentosa Plants

Target:  

Antibiotic Bacterial

Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections .
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Competence-stimulating peptide
Competence-stimulating peptide
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Cat. No.: HY-P11175
CAS No.: 438620-89-4
Target:  

Bacterial

Research Areas:  

Infection

Competence-stimulating peptide is a competence-stimulating peptide. Competence-stimulating peptide activates the Com-dependent quorum sensing system of S. mutans. Competence-stimulating peptide restores bacteriocin production .
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Strictinin
Strictinin
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Cat. No.: HY-135319
CAS No.: 517-46-4
Purity:  97.15%
Category:  

Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Theaceae

Target:  

Bacterial Antibiotic ERK JNK NF-κB ROR Apoptosis Caspase GSK-3 Akt PI3K

Strictinin is an orally active phenolic compound. Strictinin reduces xanthine oxidase activity, uric acid production, and the activation of ERK1/2, JNK, NF-κB, and NLRP3 inflammasome components in hepatocytes treated with Xanthine (HY-W017389). Strictinin decreases elevated serum uric acid levels and enhanced xanthine oxidase activity in mice treated with potassium oxonate. Strictinin acts as a ROR1 inhibitor and exhibits anticancer activity against highly aggressive non-androgen-dependent prostate cancer. Strictinin induces cancer cell apoptosis (apoptosis), arrests cell cycle, and inhibits cancer cell migration, invasion, and epithelial-mesenchymal transition. Strictinin modulates gut microbiota, inhibits bacterial growth and biofilm formation, accelerates small intestinal transit, and blocks viral entry and replication. Strictinin can be used in research related to hyperuricemia, androgen receptor-negative non-androgen-dependent prostate cancer, triple-negative breast cancer, bacterial infections, constipation, coronavirus infections, dental caries, and infections caused by influenza A, influenza B, and human parainfluenza virus type 1 .
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C16G2
C16G2
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Cat. No.: HY-P10696
CAS No.: 2154327-48-5
Target:  

Bacterial

Research Areas:  

Infection

C16G2 is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutans. C16G2 specifically recognizes and disrupts the bacterial cell membrane, causing small molecule leakage and loss of membrane potential, leading to bacterial killing. C16G2 exhibits higher selectivity and efficacy against Streptococcus mutans, unlike broad-spectrum antimicrobial peptides .
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Gypsogenic acid
Gypsogenic acid
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Cat. No.: HY-W587957
CAS No.: 5143-05-5
Target:  

Bacterial Parasite

Research Areas:  

Infection

Gypsogenic acid is a triterpenoid acid that can be isolated from Miconia stenostachya and has antibacterial and trypanoidal activities. The MICs values of Gypsogenic acid for the oral bacterial pathogens Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans and sobrinus were 50-200 μg/mL. Gypsogenic acid can induce blood cortensite cleavage in isolated mice with IC50 56.6 μM .
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Isobavachromene
Isobavachromene
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Cat. No.: HY-N2208A
CAS No.: 52801-22-6
Category:  

Infection Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields

Target:  

Bacterial

Isobavachromene is an antibacterial agent .
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Farobin A
Farobin A
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Cat. No.: HY-N12743
CAS No.: 1245447-08-8
Category:  

Zea mays L. Flavonoids Flavones Gramineae Plants

Target:  

Bacterial

Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α .
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C16G2 TFA
C16G2 TFA
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Cat. No.: HY-P10696A
Target:  

Bacterial

Research Areas:  

Infection

C16G2 TFA is a specific targeted antimicrobial peptide (STAMP) that targets the cariogenic oral pathogen Streptococcus mutans. C16G2 TFA specifically recognizes and disrupts the bacterial cell membrane, causing small molecule leakage and loss of membrane potential, leading to bacterial killing. C16G2 TFA exhibits higher selectivity and efficacy against Streptococcus mutans, unlike broad-spectrum antimicrobial peptides .
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Guaijaverin (Standard)
Guaijaverin (Standard)
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Cat. No.: HY-N2224R
CAS No.: 22255-13-6
Category:  

Flavonols Flavonoids Rosaceae Phenols Polyphenols Plants Eriobotrya japonica (Thunb.) Lindl.

Target:  

Reference Standards Bacterial

Guaijaverin (Standard) is the analytical standard of Guaijaverin. This product is intended for research and analytical applications. Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities .
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Oleanolic aldehyde
Oleanolic aldehyde
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Cat. No.: HY-N12240
CAS No.: 17020-22-3
Category:  

Triterpenes Terpenoids Vitis vinifera cv. Zalema Plants Vitaceae

Target:  

Bacterial

Oleanolic aldehyde is an antimicrobial compound used to inhibit oral bacteria. Oleanolic aldehyde inhibits Streptococcus mutans and Porphyromonas gingivalis, which are associated with dental caries and periodontal disease, with minimum inhibitory concentrations (MICs) of 488 μg/mL and 250 μg/mL, respectively .
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o-Cymen-5-ol
o-Cymen-5-ol
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Cat. No.: HY-149155
CAS No.: 39660-61-2
Target:  

Bacterial

Research Areas:  

Infection

o-Cymen-5-ol is a broad-spectrum antimicrobial agent with direct antimicrobial activity. o-Cymen-5-ol showed effective minimum inhibitory concentrations (MICs) against a variety of bacteria and fungi, such as Streptococcus mutans and Candida albicans. The combination of o-Cymen-5-ol and zinc showed synergistic effects, enhancing the inhibitory effect against oral pathogens. o-Cymen-5-ol was able to inhibit the glycolysis process and co-enhanced this effect with zinc. o-Cymen-5-ol showed a stronger antibacterial effect in toothpaste than placebo .
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