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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
THY1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "THY1" in MCE Product Catalog:
Research Areas:
R-268712 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-β signaling, which can be used in studies of renal fibrosis and cancer [1] .
Cat. No.: HY-P990157
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Cat. No.: HY-P990156
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Benarthin is an orally active Pyroglutamyl peptidase inhibitor, THY1 inhibitor (with a Kd value of 5.13e-08 M) and competitive PGP-1 inhibitor (Ki = 1.2 µM). Benarthin is isolated from the culture broth of Streptomyces xanthophaeus MJ244-SF1. Benarthin disrupts the THY1-SFRP1 interaction, inhibits the activation of the GSK3α/β-β-catenin pathway, and reduces the upregulation of FASLG. Benarthin attenuates urothelial anoikis and reduces cell Apoptosis. Benarthin possesses iron-chelating activity. Benarthin maintains urothelial barrier integrity and blocks the pathological cascade of renal interstitial fibroblasts induced by HAP stimulation. Benarthin can be used in studies related to kidney stones [1] .
Cat. No.: HY-RS17457
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Thy1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Thy1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14511
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THY1 Human Pre-designed siRNA Set A contains three designed siRNAs for THY1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23914
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Thy1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Thy1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81132
Synonyms: CD90 / THY1; CD7; CD90 antigen; CDw90; FLJ33325; MGC128895; T25; Theta antigen; THY-1; THY 1; THY 1 cell surface antigen; THY-1 membrane glycoprotein; THY 1 membrane glycoprotein precursor; THY 1.2; THY-1 T-cell antigen; THY1 antigen; THY1 T cell antigen; THY1.1; THY1.2; THYmus cell antigen 1, theta; THY1_RAT; THY1_HUMAN.
Cat. No.: HY-P76105
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: THY-1 membrane glycoprotein; THY-1 antigen; CD90; THY-1
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Cat. No.: HY-106611
CAS No.: 89622-90-2
Synonyms: SR 33287
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Brinazarone (SR 33287) is an inhibitor for acid lysosomal sphingomyelinase, and leads to cellular lipidosis. Brinazarone potentiates the cytotoxic effects of anti-Thy 1.2 AT15E RTA-IT on T2 cells and anti-CD5 T101 on CEM cells [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
