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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
TST
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "TST" in MCE Product Catalog:
8
Target:
Research Areas:
Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area .
Cat. No.: HY-P9991
CAS No.: 2460539-61-9
Synonyms: TST001
Target:
Research Areas:
Cat. No.: HY-W105505
CAS No.: 101020-79-5
Target:
Research Areas:
VU591 is a selective inhibitor of the renal outer medullary potassium channel (ROMK, Kir1.1). VU591 inhibits ROMK via binding to the intracellular pore region near residues Val168 and Asn171, with IC50 of 240 nM in Tl + flux assay and 300 nM in whole cell patch clamp electrophysiology, suppresses native ROMK mediated K + secretion in isolated perfused rat collecting ducts, and exerts antidepressive effects in the mouse tail suspension test (TST). VU591 can be used for the study of ROMK channel function, renal potassium handling, antidepressant mechanisms, and diuretic drug discovery .
Target:
Research Areas:
VU591 hydrochloride is a selective inhibitor of the renal outer medullary potassium channel (ROMK, Kir1.1). VU591 hydrochloride inhibits ROMK via binding to the intracellular pore region near residues Val168 and Asn171, with IC50 of 240 nM in Tl + flux assay and 300 nM in whole cell patch clamp electrophysiology, suppresses native ROMK mediated K + secretion in isolated perfused rat collecting ducts, and exerts antidepressive effects in the mouse tail suspension test (TST). VU591 hydrochloride can be used for the study of ROMK channel function, renal potassium handling, antidepressant mechanisms, and diuretic drug discovery .
Target:
Research Areas:
Mecamylamine is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine is also a ganglionic blocker. Mecamylamine can across the blood-brain barrier. Mecamylamine can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area .
Cat. No.: HY-162775
CAS No.: 50566-97-7
Target:
Research Areas:
TST1N-224 is a potent response regulator VraRC inhibitor. TST1N-224 can disrupt VraRC-DNA complex formation (IC50=60.2 μM). TST1N-224 exhibits interference with VraRC binding to its cognate DNA through a fast-on-fast-off binding mechanism (KD=23.4 μM). TST1N-224 predominantly interacts with the α9- and α10-helixes of the DNA-binding domain of VraR. TST1N-224 inhibits the growths of S. aureus (SA; MIC>126 μM), Methicillin-resistant S. aureus (MRSA; MIC>126 μM), and Vancomycin-intermediate S. aureus (VISA; MIC=63 μM). TST1N-224, an antimicrobial agent, evidently enhances the susceptibility of VISA to both Vancomycin (HY-B0671) and Methicillin (HY-B0974) .
Cat. No.: HY-RS23817
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Research Areas:
Tst Rat Pre-designed siRNA Set A contains three designed siRNAs for Tst gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W143822
CAS No.: 80441-55-0
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Research Areas:
6-(Tritylthio)hexanoic acid is a linker with a Tst group and a terminal carboxylic acid. The Tst group can be deprotected under acidic conditions to obtain the free thiol which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Cat. No.: HY-147735
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Research Areas:
GABAA receptor agonist 1 (compound 3e) is a potent GABAA receptor agonist. GABAA receptor agonist 1 shows anti-depression activities in classical mouse models of depression of FST and TST. GABAA receptor agonist 1 binds at the GABA binding site of GABAA receptor in order to produce GABAergic effects. GABAA receptor agonist 1 has the potential for the research of depression .
Cat. No.: HY-147736
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GABAA receptor agonist 2 (compound 4c) is a potent GABAA receptor agonist. GABAA receptor agonist 2 shows anti-depression activities in classical mouse models of depression of FST and TST. GABAA receptor agonist 2 binds at the GABA binding site of GABAA receptor in order to produce GABAergic effects. GABAA receptor agonist 2 has the potential for the research of depression .
Research Areas:
Mecamylamine (hydrochloride) (Standard) is the analytical standard of Mecamylamine (hydrochloride). This product is intended for research and analytical applications. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area .
Cat. No.: HY-RS15190
Target:
Research Areas:
TST Human Pre-designed siRNA Set A contains three designed siRNAs for TST gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17363
Target:
Research Areas:
Tst Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tst gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15191
Target:
Research Areas:
TSTD1 Human Pre-designed siRNA Set A contains three designed siRNAs for TSTD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P75418
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD37; Tspan-26; CD37 Molecule; CDNA FLJ25364 Fis, Clone TST01761, Highly Similar To LEUKOCYTE ANTIGEN CD37; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Antigen CD37; Leukocyte Surface Antigen CD37; Tetraspanin-26; Tetraspanin; CD37 Antigen; GP52-4
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P77886
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD37; Tspan-26; CD37 Molecule; CDNA FLJ25364 Fis, Clone TST01761, Highly Similar To LEUKOCYTE ANTIGEN CD37; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Antigen CD37; Leukocyte Surface Antigen CD37; Tetraspanin-26; Tetraspanin; CD37 Antigen; GP52-4
Species:
Human
Source:
HEK293
Cat. No.: HY-P704466
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD37; Tspan-26; CD37 Molecule; CDNA FLJ25364 Fis, Clone TST01761, Highly Similar To LEUKOCYTE ANTIGEN CD37; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Antigen CD37; Leukocyte Surface Antigen CD37; Tetraspanin-26; Tetraspanin; CD37 Antigen; GP52-4
Species:
Human
Source:
HEK293
Cat. No.: HY-P701276
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD37; Tspan-26; CD37 Molecule; CDNA FLJ25364 Fis, Clone TST01761, Highly Similar To LEUKOCYTE ANTIGEN CD37; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Antigen CD37; Leukocyte Surface Antigen CD37; Tetraspanin-26; Tetraspanin; CD37 Antigen; GP52-4
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
