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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
TXB 2
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "TXB 2" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N0677
CAS No.: 786593-06-4
Synonyms: Quadrisol; CERM 10202; PM 150
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Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition . Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM .
Synonyms: 11-dehydro-2,3-dinor TXB2
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11-dehydro-2,3-dinor Thromboxane B2 (11-dehydro-2,3-dinor TXB2) is a metabolite of the TXA2 inactive metabolite TXB2 (Item No. 19030). It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 are increased 5.2-fold in a surgery-induced rat model of tendon overuse.
Cat. No.: HY-177362
CAS No.: 398138-29-9
Synonyms: TXB2-EA
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Thromboxane B2 ethanolamide (TXB2-EA) is a metabolite of thromboxane A2 ethanolamide. Thromboxane B2 ethanolamide is formed from thromboxane A2 ethanolamide by hydrolysis .
Cat. No.: HY-126923
CAS No.: 63250-09-9
Synonyms: 2,3-Dinor-TXB2
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2,3-Dinor thromboxane B2 (2,3-Dinor-TXB2), a metabolite of urine, serves as an indicator of the production of thromboxane A2 (TxA2) in the body, and can be used as a tool to study the role of thromboxane in various pathophysiological processes in the human body .
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Thiazinamium (chloride) possesses potent anticholinergic and antiallergic activity and inhibits TxB2 synthesis with IC50 value of 0.2 µM. Thiazinamium (chloride) is structurally similar to H-1 antagonists Promethazine (HY-B1296). Thiazinamium (chloride) stimulates the phosphatidylcholine secretion in adult rat type II pneumocytes .
Cat. No.: HY-U00364
CAS No.: 104961-19-5
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CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.
Cat. No.: HY-111097
CAS No.: 924636-93-1
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AF3442 is a potent and selective mPGES-1 inhibitor (IC50 = 0.06 μM) which reduces monocyte PGE2 generation also in the presence of plasma proteins. AF3442 shows selectivity over other prostanoids (TXB2, PGF2α and 6-keto-PGF1α). AF3442 can be used for research in analgesia .
Cat. No.: HY-U00231
CAS No.: 127654-03-9
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KF 13218 is a potent, selective and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
Cat. No.: HY-U00170
CAS No.: 99107-52-5
Synonyms: U66858
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Bunaprolast (U66858) is a potent inhibitor of LTB4 production in human whole blood. Bunaprolast (U66858) also exhibits significant inhibition of lipoxygenase and TXB2 release.
Cat. No.: HY-165674S
Synonyms: 11-dehydo-2,3-dio TXB2-d9
Cat. No.: HY-19166
CAS No.: 144562-61-8
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E-6700 is an inhibitor of 5-LO and TXA2 synthetase, with IC50s of 16.3 μM and 0.026 μM respectively. E-6700 inhibits LTB4 and TXB2 production. E-6700 can be used for antiinflammatory research .
Cat. No.: HY-129786
CAS No.: 91505-18-9
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LG 82-4-00 is a thromboxane (TX) synthase inhibitor with an IC50 value of 1.1 μM. LG 82-4-00 can inhibit collagen-induced TXB2 formation and platelet aggregation in plasma. LG 82-4-00 can be used in studies related to thrombotic diseases .
Cat. No.: HY-118827S
CAS No.: 1185054-34-5
Cat. No.: HY-118827R
CAS No.: 71109-09-6
Synonyms: Quadrisol (Standard); CERM 10202 (Standard); PM 150 (Standard)
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Vedaprofen (Standard) is the analytical standard of Vedaprofen. This product is intended for research and analytical applications. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition . Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM .
Cat. No.: HY-105424
CAS No.: 83863-79-0
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Florifenine is a selective cyclooxygenase (COX) inhibitor with anti-inflammatory activity. Florifenine inhibits TXB2 in human whole blood with an IC50 of 32.5 nM. Florifenine exhibits anti-inflammatory effects in ear oedema. Florifenine inhibits neutrophil migration and reduces PGE2 levles in the inflamed ears. Florifenine inhibits leukocyte migration and PGE2 levels in the air pouch inflammation induced by Zymosan (HY-159069). Florifenine can be used for anti-inflammatory research .
Cat. No.: HY-W966480
CAS No.: 68548-99-2
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Oxindanac is a nonsteroidal anti-inflammatory agent. Oxindanac produces inhibition of serum TxB2 production. Oxindanac reduces the volume of swelling. Oxindanac shows analgesic activity .
Cat. No.: HY-N19723
CAS No.: 139501-36-3
Synonyms: Verbascosaponin B
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Cat. No.: HY-120095
CAS No.: 155944-23-3
Synonyms: ICI-230487
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ZM 230487 (ICI-230487) is an orally active, selective, non-redox 5-lipoxygenase (5-LO) inhibitor. ZM 230487 potently inhibits antigen-induced LTD4 release (IC50 ≈ 0.2 µM), but does not affect the release of TXB2 and histamine . ZM 230487 specifically blocks eosinophil accumulation and partial bronchoconstriction in guinea pig models . ZM 230487 can be used in studies related to allergic inflammation .
Cat. No.: HY-183433
CAS No.: 99435-38-8
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Ph CL 28A is a prostaglandin dehydrogenase (PGDH) inhibitor. Ph CL 28A increases the output of PGE2, PGF2α and endogenous arachidonic acid-derived PGI2 in isolated rat lungs, reduces the output of TxB2 and LTC4 in isolated rat hearts, and exhibits protective effects in rat models of inflammation and gastric mucosal injury. Ph CL 28A can be used in research related to acute inflammation and gastric ulcers .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
