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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
VE-Cadherin
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "VE-Cadherin" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-125864B
CAS No.: 9001-32-5
Research Areas:
Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .
2
2 Cited Publications
Cat. No.: HY-P81097
Synonyms: VE-Cadherin; 7B4 antigen; VECD; Vascular endothelial cell Cadherin; 7B 4; 7B4; 7B4 antigen; Cadherin 5; Cadherin 5 type 2; Cadherin-5; Cadherin5; CD 144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Vascular endothelial Cadherin; VE Cad antibody VEC; CADH5_HUMAN.
Target:
Cat. No.: HY-P10580
CAS No.: 1359657-45-6
Research Areas:
Synonyms: Fibrin-deriVEd peptide Bβ15-42
Target:
Research Areas:
Cat. No.: HY-P10580A
Research Areas:
Cat. No.: HY-P73557
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH5; Cadherin 5, Type 2, VE-Cadherin (Vascular Epithelium); Cadherin 5; Cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial Cadherin; 7B4 Antigen; VE-Cadherin; CDNA FLJ51088, Highly Similar To Cadherin-5; Cadherin-5; Endothelial-Specific Cadh
Species:
Rat
Source:
HEK293
Cat. No.: HY-P73559
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDH5; Cadherin 5, Type 2, VE-Cadherin (Vascular Epithelium); Cadherin 5; Cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial Cadherin; 7B4 Antigen; VE-Cadherin; CDNA FLJ51088, Highly Similar To Cadherin-5; Cadherin-5; Endothelial-Specific Cadh
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P73560A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDH5; Cadherin 5, Type 2, VE-Cadherin (Vascular Epithelium); Cadherin 5; Cadherin 5, Type 2 (Vascular Endothelium); Vascular Endothelial Cadherin; 7B4 Antigen; VE-Cadherin; CDNA FLJ51088, Highly Similar To Cadherin-5; Cadherin-5; Endothelial-Specific Cadh
Species:
Human
Source:
HEK293
Cat. No.: HY-183377
CAS No.: 1260071-76-8
Target:
EGFR Akt MMP HIF/HIF Prolyl-Hydroxylase mTOR VEGFR NF-κB Reactive Oxygen Species (ROS) Cadherin
Research Areas:
DMBT is an orally effective anti-tumor metastasis and anti-angiogenesis agent. DMBT downregulates key molecules such as EGFR/p-Akt/HIF-1α/VEGF/MMP-9, inhibits the HIF-1α/VE-cadherin (cadherin)/MMPs and Nrf2/HO-1 signaling pathways, and reduces hypoxia-induced ROS levels as well as the secretion and activity of MMP-9. DMBT inhibits hypoxia-induced vasculogenic mimicry, cancer cell migration, invasion and metastasis, and exhibits no obvious cytotoxicity to normal cells. DMBT reduces the area of laser-induced choroidal neovascularization lesions. DMBT can be used in studies related to breast cancer, melanoma and macular degeneration .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
