Search Result
Results for "
agricultural pests
" in MedChemExpress (MCE) Product Catalog:
1
Bibliotecas de Screening
5
Isotope-Labeled Compounds
| Cat. No. |
Nombre del producto |
Target |
Áreas de investigación |
Chemical Structure |
-
- HY-15311
-
-
-
- HY-118504
-
|
|
Environmental Pollutants
nAChR
|
Neurological Disease
|
|
Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the α-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc .
|
-
-
- HY-B0827
-
|
MTI-446
|
Environmental Pollutants
Parasite
nAChR
|
Infection
Cardiovascular Disease
|
|
Dinotefuran is an orally active and competitive inhibitor and insecticide targeting insect nicotinic acetylcholine receptors (nAChRs). Dinotefuran blocks neural signaling and induces neural dysfunction in insects. Dinotefuran binds to [ 3H]epibatidine in the neural cord membrane of American cockroach with an IC50 of 890 nM and to [ 3H]α-bungarotoxin with an IC50 of 36.1 μM. Dinotefuran exhibits knockdown activity (KD50=0.351 nmol/g) and lethal activity (LD50=0.173 nmol/g) against German cockroach. Dinotefuran is mainly used for agricultural pest control, such as field control of piercing-sucking and chewing insects (e.g., aphids, planthoppers), while its environmental toxicological effects (e.g., oxidative stress and reproductive neurotoxicity on earthworms) are also a research focus to assess ecological risks .
|
-
-
- HY-B1072A
-
|
(-)-trans-Phenothrin
|
Parasite
|
Infection
|
|
D-Phenothrin ((-)-trans-Phenothrin), an orally active Type II synthetic pyrethroid, is widely used to kill insects, mosquitoes, and human lice. D-Phenothrin is also used in veterinary medicine to control insect pests on animals and protect agricultural crops .
|
-
-
- HY-B1837
-
|
|
Environmental Pollutants
Sodium Channel
|
Infection
|
|
Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product .
|
-
-
- HY-B1953
-
|
|
Environmental Pollutants
Insecticide
nAChR
|
Infection
|
|
Thiacloprid is an orally active neurotoxic insecticide and also a nAChR agonist. Thiacloprid reduces the viability of healthy cells, depletes reduced glutathione, and increases MDA levels, thereby inducing cytotoxicity and oxidative stress damage. In practical applications, Thiacloprid has lower acute toxicity to honeybees than other compounds of the same class such as Imidacloprid (HY-B0838), but it still significantly impairs the learning and memory function, immune capacity and survival status of honeybees. Thiacloprid induces intestinal microbial dysbiosis and reduces survival rate in middle-aged honeybees, increases the risk of premature collapse in bumblebee colonies, and significantly decreases the final colony weight and reproductive output. Thiacloprid is used in broad-spectrum agricultural pest control, often alone or in combination with Deltamethrin (HY-B1971), and meets the pest management needs of various crops including potatoes, cabbages, various fruits and vegetables, and nuts .
|
-
-
- HY-B0816
-
|
|
Environmental Pollutants
Insecticide
|
Others
Cancer
|
|
Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
-
- HY-B1072
-
|
|
Environmental Pollutants
Parasite
Insecticide
|
Infection
|
|
Phenothrin is a Type I pyrethroid insecticide. Phenothrin induces dose-dependent DNA damage in human peripheral blood lymphocytes and hepatocytes, and exhibits definite genotoxic potential. Phenothrin acts as an insecticide for pest control in agriculture, households and public health, as well as for the elimination of human head lice infestations .
|
-
-
- HY-122062
-
-
-
- HY-177552
-
|
|
GABA Receptor
Chloride Channel
Insecticide
|
Infection
|
|
4''-Oxoavermectin B1a is a potentiator targeting GABA (γ-aminobutyric acid) and glutamate-gated chloride channels with insecticidal and acaricidal activities. 4''-Oxoavermectin B1a is promising for research of agricultural pests .
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- HY-N16475
-
|
|
nAChR
|
Infection
|
|
Spinosyn L is a selective nicotinic acetylcholine receptors (nAChR) agonist. Spinosyn L causes sustained neural excitation and paralysis in insects. Spinosyn L is promising for research of pesticides for controlling Lepidoptera, Diptera, and other agricultural pests .
|
-
-
- HY-B1970
-
|
2,4'-DDT
|
Insecticide
Estrogen Receptor/ERR
|
Endocrinology
|
|
o,p'-DDT (2,4'-DDT) is a chlorinated organic pesticide with estrogenic activity. o,p'-DDT is persistent in the environment, can accumulate in organisms and disrupt the endocrine system. o,p'-DDT is used in agriculture as a pesticide, especially for controlling insect pests. The use of o,p'-DDT has led to toxic effects in organisms, raising widespread concern about its environmental and health effects. o,p'-DDT has also led to research into its long-term effects in ecosystems .
|
-
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- HY-15311R
-
|
Abamectin (Standard); Avermectin B1a-Avermectin B1b mixt. (Standard)
|
Reference Standards
Parasite
Autophagy
Apoptosis
Reactive Oxygen Species (ROS)
Antibiotic
|
Infection
Inflammation/Immunology
|
|
Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .
|
-
-
- HY-163776
-
|
|
Parasite
|
Others
|
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Insecticidal agent 13 (compound A15) is a phenylpyrazole derivative with insecticidal and acaricidal activities, which can be used in the research of agricultural pest control .
|
-
-
- HY-Z8942
-
|
|
Insecticide
Parasite
Chloride Channel
|
Infection
|
|
Avermectin B2a is an insecticide targeting glutamate-gated chloride channels (GluCls). Avermectin B2a causes hyperpolarization of nematode/insect neurons and subsequent paralysis/death. Avermectin B2a is promising for research of agricultural pests .
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- HY-W750355
-
|
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Insecticide
|
Infection
|
|
Azadirachtin D is an insect growth regulator targeting ecdysone receptor (EcR) in insects. Azadirachtin D blocks the 20-hydroxyecdysone signaling pathway, leading to developmental arrest or death in insects. Azadirachtin D is promising for research of agricultural pests .
|
-
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- HY-126744
-
|
|
Parasite
|
Others
|
|
Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm [2].
|
-
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- HY-W740651
-
|
|
Insecticide
Sodium Channel
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Infection
|
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Jasmolin II is an insecticide targeting voltage-gated sodium channels in insects. Jasmolin II leads to neuronal hyperexcitation and insect paralysis. Jasmolin II is promising for research of agricultural pests .
|
-
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- HY-B1953R
-
|
|
Reference Standards
nAChR
Insecticide
|
Infection
|
|
Thiacloprid (Standard) is the analytical standard of Thiacloprid. This product is intended for research and analytical applications. Thiacloprid is an orally active neurotoxic insecticide and also a nAChR agonist. Thiacloprid reduces the viability of healthy cells, depletes reduced glutathione, and increases MDA levels, thereby inducing cytotoxicity and oxidative stress damage. In practical applications, Thiacloprid has lower acute toxicity to honeybees than other compounds of the same class such as Imidacloprid (HY-B0838), but it still significantly impairs the learning and memory function, immune capacity and survival status of honeybees. Thiacloprid induces intestinal microbial dysbiosis and reduces survival rate in middle-aged honeybees, increases the risk of premature collapse in bumblebee colonies, and significantly decreases the final colony weight and reproductive output. Thiacloprid is used in broad-spectrum agricultural pest control, often alone or in combination with Deltamethrin (HY-B1971), and meets the pest management needs of various crops including potatoes, cabbages, various fruits and vegetables, and nuts .
|
-
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- HY-W109323
-
|
(E)-8-Dodecen-1-yl acetate; trans-8-Dodecenyl acetate
|
Olfactory Receptor
|
Infection
|
|
(E)-8-Dodecenyl ((E)-8-Dodecen-1-yl; trans-8-Dodecenyl) acetate is a sex pheromone targeting the olfactory receptors of male Gymnandrosoma aurantianum moths. acting as an agonist. (E)-8-Dodecenyl acetate is promising for research of agricultural pests .
|
-
-
- HY-15308B
-
|
|
Parasite
Chloride Channel
|
Neurological Disease
|
|
Δ²-Avermectin B₁ₐ (Compound 3) is an antiparasitic agent targeting glutamate-gated chloride channels (GluCls) in the neuromuscular system of invertebrates. Δ²-Avermectin B₁ₐ enhances chloride ion influx, leading to hyperpolarization of the neuromuscular cell membrane, inhibition of neural signal transmission, and ultimately paralysis and death of parasites. Δ²-Avermectin B₁ₐ is promising for research of agricultural pests .
|
-
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- HY-126772
-
|
|
Insecticide
|
Infection
|
|
Tralomethrin is a pyrethroid insecticide used to control a wide range of pests in agriculture and public health .
|
-
-
- HY-W706237
-
|
|
Isotope-Labeled Compounds
Insecticide
|
Infection
|
|
Tralomethrin-d5 is the deuterium labeled Tralomethrin (HY-126772). Tralomethrin is a pyrethroid insecticide used to control a wide range of pests in agriculture and public health .
|
-
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- HY-N16476
-
|
|
GABA Receptor
nAChR
|
Infection
|
|
Spinosyn J is a non-competitive insect nicotinic acetylcholine receptor (nAChR) and γ-aminobutyric acid (GABA) receptor modulator with insecticidal activity. Spinosyn J is promising for research of agricultural pests .
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- HY-W488109
-
|
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Insecticide
|
|
|
Genite is a highly effective pesticide with strong insecticidal activity. Genite can effectively control the number of various pests and is widely used in agricultural production. The use of Genite can significantly increase the yield and quality of crops.
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-
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- HY-B0816R
-
|
|
Insecticide
Reference Standards
|
Others
|
|
Etofenprox (Standard) is the analytical standard of Etofenprox. This product is intended for research and analytical applications. Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
-
- HY-W718786
-
|
|
Isotope-Labeled Compounds
Insecticide
|
Cancer
|
|
Etofenprox-phenol-d5 is the deuterium labeled Etofenprox (HY-B0816). Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
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- HY-W420337
-
|
LH2010A
|
Reactive Oxygen Species (ROS)
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Infection
|
|
Fluopimomide (LH2010A) is a potent pesticide, widely used for agricultural pest management. Fluopimomide adversely affects the nematodes growth, locomotive behaviors, reproduction, and lifespan, accompanying with enhanced of reactive oxygen species (ROS) generation, lipid and lipofuscin accumulation, and malondialdehyde content. Fluopimomide inhibits antioxidant systems in the nematodes .
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-
-
- HY-118839
-
|
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Endogenous Metabolite
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Infection
|
|
Trans-Phenothrin is a synthetic pyrethroid with activity against adult fleas and ticks. Trans-Phenothrin has shown significant differences in biological activity between its different enantiomers in comparison with fenvalerate and d-trans-phenothrin. Trans-Phenothrin is used in agriculture for its potential insecticide activity against pests such as Plutella xylostella .
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-
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- HY-B1837R
-
|
|
Reference Standards
Sodium Channel
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Infection
|
|
Cyfluthrin (Standard) is the analytical standard of Cyfluthrin. This product is intended for research and analytical applications. Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture,veterinary, insecticide,pyrethroid and stored product[1][2].
|
-
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- HY-174441
-
|
|
Chloride Channel
|
Others
|
|
Molluscicidal agent-2 (Compound 16) is a molluscicide with an LC50 of 0.58 mg/mL against Monacha cartusiana snails. Molluscicidal agent-2 exerts its effect through a dual mode of action: gastrointestinal toxicity and GABAA-GluCl channel antagonism. Molluscicidal agent-2 can be used in research on agricultural pest control .
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- HY-N16479
-
|
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Insecticide
|
Infection
|
|
Azadirachtin I is an insecticide targeting insect growth and development-related pathways (e.g., ecdysone signaling pathway, chitin synthesis pathway). Azadirachtin I inhibits chitin synthesis and disrupting intestinal function by interfering with the growth and development processes of insect larvae such as molting and pupation, increasing insect mortality and reducing adult fecundity. Azadirachtin I is promising for research of agricultural pests, such as Lepidoptera, Coleoptera .
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-
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- HY-B1072R
-
|
|
Reference Standards
Parasite
Environmental Pollutants
Insecticide
|
Infection
|
|
Phenothrin (Standard) is the analytical standard of Phenothrin (HY-B1072). This product is intended for research and analytical applications. Phenothrin is a Type I pyrethroid insecticide. Phenothrin induces dose-dependent DNA damage in human peripheral blood lymphocytes and hepatocytes, and exhibits definite genotoxic potential. Phenothrin acts as an insecticide for pest control in agriculture, households and public health, as well as for the elimination of human head lice infestations.
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-
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- HY-162778
-
|
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Parasite
|
Infection
|
|
FM-1088 is an insecticide. FM-1088 can be used in research related to crop disease and insect pest control .
|
-
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- HY-118504S
-
|
|
Isotope-Labeled Compounds
nAChR
|
Neurological Disease
|
|
Sulfoxaflor-d3 is the deuterium labeled Sulfoxaflor (HY-118504). Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the α-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc .
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-
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- HY-B1953S
-
|
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nAChR
Insecticide
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Infection
|
|
Thiacloprid-d4 is the deuterium labeled Thiacloprid. Thiacloprid is an orally active neurotoxic insecticide and also a nAChR agonist. Thiacloprid reduces the viability of healthy cells, depletes reduced glutathione, and increases MDA levels, thereby inducing cytotoxicity and oxidative stress damage. In practical applications, Thiacloprid has lower acute toxicity to honeybees than other compounds of the same class such as Imidacloprid (HY-B0838), but it still significantly impairs the learning and memory function, immune capacity and survival status of honeybees. Thiacloprid induces intestinal microbial dysbiosis and reduces survival rate in middle-aged honeybees, increases the risk of premature collapse in bumblebee colonies, and significantly decreases the final colony weight and reproductive output. Thiacloprid is used in broad-spectrum agricultural pest control, often alone or in combination with Deltamethrin (HY-B1971), and meets the pest management needs of various crops including potatoes, cabbages, various fruits and vegetables, and nuts .
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-
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- HY-W747609
-
|
|
Parasite
|
Infection
|
|
Butoxycarboxim is an organophosphate insecticide/acaricide mainly used in agriculture to control a variety of pests.
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-
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- HY-W719559
-
|
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Insecticide
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Infection
|
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Cyclaniliprole is an insecticide and insect ryanodine receptor modulator with higher selectivity for insect ryanodine receptors than for mammalian ones. Cyclaniliprole exerts lethal effects on larvae and adults of various agricultural pests. Cyclaniliprole exhibits broad-spectrum insecticidal activity against pests of the orders Lepidoptera, Thysanoptera, Diptera, Hemiptera and Coleoptera .
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-
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- HY-N20623
-
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Drug Intermediate
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Others
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(+)-Todomatuic acid is a naturally occurring sesquiterpenoid, and its derivatives juvabiones exhibit juvenile hormone-like activity in insects as well as antifungal activity. (+)-Todomatuic acid can be used in research on the regulation of agricultural pests and the inhibition of phytopathogenic fungi .
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-
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- HY-W747601
-
|
|
Cholinesterase (ChE)
SOD
Reactive Oxygen Species (ROS)
Bcl-2 Family
MDM-2/p53
Apoptosis
Insecticide
|
Infection
|
|
Chlorphoxim is a broad-spectrum and highly efficient insecticide. Chlorphoxim kills pests by inhibiting AChE. Chlorphoxim inhibits the activities of SOD and CAT in zebrafish embryos. Chlorphoxim induces oxidative stress in zebrafish embryos by activating ROS. Chlorphoxim induces apoptosis by upregulating the expression levels of Bax, Bcl2 and p53 in zebrafish embryos. Chlorphoxim exhibits neurotoxicity and developmental toxicity. Chlorphoxim is used in agricultural research for the control of various pests .
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-
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- HY-N16837
-
|
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Insecticide
|
Infection
|
|
6''-O-β-D-Apiofuranosylastragalin (compound 1) is a flavonoid glycoside that can be naturally extracted from the methanol extract of fresh leaves of Solidago altissima L. (a plant of the genus Solidago in the Asteraceae family). The related methanol extract exhibits antifeedant activity against Thrips palmi and can be used in the research of natural antifeedants for agricultural pest control .
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-
-
- HY-N18288
-
|
|
Insecticide
|
Infection
|
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6''-O-(3'''-Hydroxy-3'''-methylglutaryl) vitexin is an orally active flavonoid glycoside and insecticide that can be isolated from the twigs of Eleusine coracana. 6''-O-(3'''-Hydroxy-3'''-methylglutaryl) vitexin exhibits distinct antifeedant activity against Nilaparvata lugens (brown planthopper) nymphs and effectively inhibits their feeding behavior. 6''-O-(3'''-Hydroxy-3'''-methylglutaryl) vitexin can serve as a plant-derived natural defense substance for regulating pest behavior and investigating potential control mechanisms of agricultural pests .
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-
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- HY-124920
-
|
Mercaptodimethur
|
Insecticide
SOD
Glutathione Peroxidase
Reactive Oxygen Species (ROS)
Cholinesterase (ChE)
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Infection
Inflammation/Immunology
|
|
Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals .
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-
-
- HY-W720758
-
|
|
Insecticide
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Infection
|
|
3,7,11-Trimethyl-1-dodecanol is an alcohol volatile organic compound present in Spirulina platensis, with a faint odor. 3,7,11-Trimethyl-1-dodecanol inhibits the oviposition behavior of female Ostrinia nubilalis (European corn borer). 3,7,11-Trimethyl-1-dodecanol can be used in studies related to behavioral regulation of agricultural pests .
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-
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- HY-124920S
-
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Mercaptodimethur-d3
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Isotope-Labeled Compounds
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Infection
Inflammation/Immunology
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Methiocarb-d3 is the deuterium labeled Methiocarb (HY-124920). Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals .
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- HY-W753728
-
|
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Insecticide
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Infection
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|
Xiaochongliulin is a organophosphate insecticide. Xiaochongliulin shows insecticidal activity against citrus red mite, citrus scales, cotton bollworm, diamondback moth, and rice planthopper. Xiaochongliulin has low acute oral toxicity in rats .
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| Cat. No. |
Nombre del producto |
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HY-L183
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518 compounds
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Pesticide is a single substance or mixture that can be used to prevent, mitigate, iminate pests or as a plant conditioner, defoliant or desiccant. In recent years, scientists have proposed the concept of "Molecules to Ecosystems", bringing the concept of molecular biology to understand the impact of pesticides, degradation and relationship with the environment or organisms. MCE integrates effective compounds approved as pesticides by agencies such as the Environmental Protection Agency (EPA), China Pesticide Information Network and some insecticidal compounds with potential for agricultural applications.
MCE can provide a library of 518 pesticide compounds that are tool compounds for relevant research.
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| Cat. No. |
Nombre del producto |
Category |
Target |
Chemical Structure |
| Cat. No. |
Nombre del producto |
Chemical Structure |
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- HY-W706237
-
|
|
|
Tralomethrin-d5 is the deuterium labeled Tralomethrin (HY-126772). Tralomethrin is a pyrethroid insecticide used to control a wide range of pests in agriculture and public health .
|
-
-
- HY-W718786
-
|
|
|
Etofenprox-phenol-d5 is the deuterium labeled Etofenprox (HY-B0816). Etofenprox is an orally active non-ester pyrethroid insecticide. Etofenprox induces toxicity against many pest insects, including Diptera rather than mammalian and fish. Etofenprox has a liver tumor-promoting activity in rats accompanied with microsomal ROS production increase. Etofenprox can be used in agricultural pest control and malaria research .
|
-
-
- HY-118504S
-
|
|
|
Sulfoxaflor-d3 is the deuterium labeled Sulfoxaflor (HY-118504). Sulfoxaflor is an orally active full agonist of insect nicotinic acetylcholine receptors (nAChRs), targeting the α-bungarotoxin-insensitive nAChR1 and nAChR2 subtypes. Sulfoxaflor binding to nACh is not inhibited by d-Tubocurarine (HY-125901), but is partially inhibited by Mecamylamine (HY-B1395A). Sulfoxaflor induces inward currents by activating nAChRs, leading to insect neurotoxicity. Sulfoxaflor can be used in the research of agricultural pest control, pesticide toxicology, insect neural receptor pharmacology, etc .
|
-
-
- HY-B1953S
-
|
|
|
Thiacloprid-d4 is the deuterium labeled Thiacloprid. Thiacloprid is an orally active neurotoxic insecticide and also a nAChR agonist. Thiacloprid reduces the viability of healthy cells, depletes reduced glutathione, and increases MDA levels, thereby inducing cytotoxicity and oxidative stress damage. In practical applications, Thiacloprid has lower acute toxicity to honeybees than other compounds of the same class such as Imidacloprid (HY-B0838), but it still significantly impairs the learning and memory function, immune capacity and survival status of honeybees. Thiacloprid induces intestinal microbial dysbiosis and reduces survival rate in middle-aged honeybees, increases the risk of premature collapse in bumblebee colonies, and significantly decreases the final colony weight and reproductive output. Thiacloprid is used in broad-spectrum agricultural pest control, often alone or in combination with Deltamethrin (HY-B1971), and meets the pest management needs of various crops including potatoes, cabbages, various fruits and vegetables, and nuts .
|
-
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- HY-124920S
-
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|
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Methiocarb-d3 is the deuterium labeled Methiocarb (HY-124920). Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals .
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