90 Results for "

antiplasmodial

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "antiplasmodial" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0740
CAS No.: 6681-15-8
Jatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
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4
4 Cited Publications
Cat. No.: HY-N0749A
CAS No.: 483-43-2
Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
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1
1 Cited Publications
Cat. No.: HY-122966
CAS No.: 115063-39-3
Purity:  99.66%
Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities .
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1
1 Cited Publications
Cat. No.: HY-N6009
CAS No.: 33390-41-9
8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE) . 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum . 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM .
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1 Cited Publications
Cat. No.: HY-N5107
CAS No.: 41689-51-4
Synonyms: (+)-epi-Magnolin
Epimagnolin A, a furfuran lignan, shows mild antiplasmodial activities (IC50=5.7 μg/mL) without noticeable toxicity on mammalian normal cells .
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Cat. No.: HY-N0749
CAS No.: 3621-38-3
Jatrorrhizine is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine is a potent and orally active inhibitor of AChE (IC50=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .
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Cat. No.: HY-N1581
CAS No.: 76-78-8
Synonyms: Nigakilactone D
Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity .
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Cat. No.: HY-N1198
CAS No.: 23141-25-5
Strictosamide is a compound that can be isolated from Nauclea officinalis. Strictosamide has various activities such as anti-inflammatory, analgesic, anti-Plasmodium, antifungal, and promoting wound healing .
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Cat. No.: HY-N5109
CAS No.: 138664-32-1
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC50s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively .
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Cat. No.: HY-E70250
CAS No.: 114414-78-7
Synonyms: Cryptotackieine
Neocryptolepine (Cryptotackieine) has antiplasmodial activity. Neocryptolepine also shows antibacterial activity against Gram-positive bacteria (MIC < 100 μg/mL), and antifungal activity .
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Cat. No.: HY-N8349
CAS No.: 191349-10-7
19,20-Epoxycytochalasin D, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin D shows potent in vitro antiplasmodial activity and phytotoxicity .
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Cat. No.: HY-N6251
CAS No.: 149155-01-1
Cratoxylone, isolated from the bark of Cratoxylum Cochinchinense, possesses antiplasmodial activity .
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Cat. No.: HY-N5005
CAS No.: 4758-99-0
Synonyms: Atisinium chloride
Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively .
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Cat. No.: HY-N2380
CAS No.: 132201-33-3
N-Benzoyl-(2R,3S)-3-phenylisoserine is the C-13 chiral side chain of paclitaxel and serves as a synthetic scaffold for constructing paclitaxel and related hybrid molecules. N-Benzoyl-(2R,3S)-3-phenylisoserine is used in studies on paclitaxel side chain synthesis and the design of anti-Plasmodium hybrid molecules .
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Cat. No.: HY-N9343
CAS No.: 22611-36-5
Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB) .
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Cat. No.: HY-N4037
CAS No.: 606-91-7
Synonyms: (-)-Homopterocarpin; 3,9-Dimethoxypterocarpan
Homopterocarpin is an isoflavonoid that can be isolated from Pterocarpus erinaceus. Homopterocarpin has hepatoprotective, antioxidant and antiplasmodial activity. Homopterocarpin is a competitive reversible inhibitor of human monoamine oxidase-B with an IC50 and a Ki of 0.72 and 0.21 μM for hMAO-B, respectively. Homopterocarpin can be used for the research of liver injury and oxidative stress .
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Cat. No.: HY-N7985
CAS No.: 69359-09-7
Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity .
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Cat. No.: HY-N4307
CAS No.: 72361-67-2
Laetanine is a noraporphine alkaloid from Litsea laeta, exhibits antiplasmodial activity. Laetanine can be found in the extract of the leaves of Phoebe tavoyana (Meissn) Hook .
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Cat. No.: HY-N11031
CAS No.: 111479-04-0
Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC50 value of 27 µM for W2 strain of Plasmodium falciparum .
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Cat. No.: HY-N15748
CAS No.: 287974-44-1
Synonyms: (-)-Pelorol
Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC50 of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC50 values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria .
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