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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
apoB
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "apoB" in MCE Product Catalog:
5
5 Cited Publications
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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5
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5
5 Cited Publications
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4
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Mipomersen sodium (ISIS 301012) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen sodium can be used for the research of homozygous familial hypercholesterolemia (HoFH) .
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Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen can be used for the research of homozygous familial hypercholesterolemia (HoFH) .
Synonyms: LY3473329
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Muvalaplin (LY3473329) is an orally active small molecule apolipoprotein a (apolipoprotein a) inhibitor that binds to the KIV8 domain (Kd = 22 nM) and kringle IV domains 7 and 8, blocks the non-covalent interaction between apo (a) and apoB-100, and prevents Lp (a) assembly, thereby lowering circulating Lp (a) levels. Muvalaplin can be used in research on atherosclerotic cardiovascular disease .
Cat. No.: HY-18778
CAS No.: 866399-87-3
Synonyms: TA-8995; DEZ-001; AMG-899
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Obicetrapib (TA-8995; DEZ-001) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib potently reduces atherogenic lipoproteins (such as LDL-C, ApoB, Lp (a)) and increases HDL-C. Obicetrapib can be used for the research of dyslipidemia and atherosclerotic cardiovascular disease (ASCVD) .
Cat. No.: HY-P99822
CAS No.: 2361290-85-7
Synonyms: SHR-1209
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Cat. No.: HY-W588264
CAS No.: 10468-90-3
Synonyms: 3-Monoiodothyronine
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3-Iodo-L-thyronine (3-Monoiodothyronine) is a thyroid hormone metabolite. 3-iodo-L-thyronine can bind to apolipoprotein B-100 (apoB-100) .
Cat. No.: HY-46749
CAS No.: 2565656-71-3
Synonyms: LY3473329 tetrahydrochloride
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Muvalaplin tetrahydrochloride (LY3473329 tetrahydrochloride) is an orally active small molecule apolipoprotein a (apolipoprotein a) inhibitor that binds to the KIV8 domain (Kd = 22 nM) and kringle IV domains 7 and 8, blocks the non-covalent interaction between apo (a) and apoB-100, and prevents Lp (a) assembly, thereby lowering circulating Lp (a) levels. Muvalaplin tetrahydrochloride can be used in research on atherosclerotic cardiovascular disease .
Cat. No.: HY-171464
CAS No.: 2924841-79-0
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Lp(a)-IN-5 (Compound A) is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases .
Cat. No.: HY-177291
CAS No.: 256397-11-2
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LAB687 is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 0.9 nM for apolipoprotein B (apoB) secretion in HepG2 cells. LAB687 also acts as a Smoothened (Smo) antagonist, with IC50 values of 2.48 μM and 3.42 μM against mouse and human Smo receptors, respectively. LAB687 reduces triglyceride and low-density lipoprotein cholesterol (LDL-C) levels, and inhibits the Hedgehog signaling pathway. LAB687 can be used in studies related to Hedgehog-dependent cancers .
Cat. No.: HY-171464A
CAS No.: 2924841-80-3
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Lp(a)-IN-5 (Compound A) hydrochloride is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 hydrochloride inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 hydrochloride is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases .
Cat. No.: HY-P991574
CAS No.: 2643310-75-0
Synonyms: REG-101
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Cat. No.: HY-173323
CAS No.: 3070232-49-1
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Lp(a)-IN-7 (example 1) is a lipoprotein (a) (Lp(a)) formation inhibitor with an IC50 of 2.51 nM in conditioned media containing apolipoprotein B (apoB) and apolipoprotein(a). Lp(a)-IN-7 can be used for the study of cardiovascular disease .
Cat. No.: HY-P10188
CAS No.: 255822-48-1
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Cat. No.: HY-RS00833
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APOB Human Pre-designed siRNA Set A contains three designed siRNAs for APOB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24199
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Apob Rat Pre-designed siRNA Set A contains three designed siRNAs for Apob gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P7524
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoB; Lipoprotein B; Apolipoprotein B; apoB Protein; Apolipoprotein B-100; Apo B-100; apoB-100; apoB-48; Apolipoprotein B (Including Ag(X) Antigen); LDLCQ4; Alternative Protein apoB; FCHL2; Apolipoprotein B48; FLDB
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Human
Source:
E. coli
Cat. No.: HY-RS17734
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Apob Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apob gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
