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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
crystal structures
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "crystal structures" in MCE Product Catalog:
Cat. No.: HY-154487
CAS No.: 25637-84-7
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Glycerol dioleate is a lipid capable of forming Lyotropic Liquid Crystal (LLC). When formulated with phosphatidylcholine and exposed to aqueous media, glycerol dioleate constructs an inverted hexagonal (HII) phase structure with sustained-release properties. The in-situ forming gel prepared by optimizing glycerol dioleate with phosphatidylcholine and N-methyl-2-pyrrolidone enables stable release of Risperidone (HY-11018) for up to 60 days in vitro and in vivo. Glycerol dioleate causes minimal side effects in rabbits, making it an ideal carrier component for the development of antischizophrenia agents .Note: Lyotropic liquid crystals (Lyotropic Liquid Crystal, LLC) are ordered fluid phases self-assembled by amphipathic molecules (e.g., lipids, surfactants) in solvents (usually water) at specific concentrations .
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Bis-PEG4-NHS ester is a crosslinking reagent and amine-reactive modulator .Bis-PEG4-NHS ester reacts with primary amine groups on liposome surfaces via amide bond formation to covalently attach dibenzylcyclooctyne groups, with a hydrophilic PEG4 spacer reducing steric hindrance for subsequent click chemistry .Bis-PEG4-NHS ester enables site-specific antibody coupling to liposome surfaces via copper-free strain-promoted alkyne-azide cycloaddition click chemistry without disrupting liposome structure in minimal organic solvent volumes .Bis-PEG4-NHS ester undergoes hydrolysis during annealing to form -COOH groups that interact with PbI and FAI to enhance perovskite structural integrity, passivate defects, and modulate nucleation kinetics to regulate crystal growth .Bis-PEG4-NHS ester enhances device efficiency and long-term stability when used as an antisolvent additive for p-i-n perovskite solar cells .
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Barium sulfate (Baryta white) is a poorly soluble inorganic barium salt that can serve as an oral radiocontrast agent. Barium sulfate precipitates in the form of crystals with a porous internal structure. Barium sulfate is a mineral scale compound. Barium sulfate can be used in research on diagnostic imaging .
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2-Methylimidazole (2-Methyl-1H-imidazole) is a nitrogen-containing MOF ligand that serves as a laccase-mimicking activity enhancer and a morphology regulator for copper-based metal-organic frameworks. 2-Methylimidazole promotes the formation of natural laccase-like nanoenzyme structures, accelerates electron transfer and enhances catalytic activity. During hydrothermal synthesis, 2-Methylimidazole inhibits the vertical growth of crystals, thus enabling the preparation of two-dimensional nanosheet morphology .
Cat. No.: HY-Y1359S
CAS No.: 1173022-19-9
Synonyms: 2-Methyl-1H-imidazole-d6
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Rutaceae Extract Plant Flavonoids Flavonones Disease Research Fields Citrus Extract Cancer
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Cat. No.: HY-121125
CAS No.: 64274-28-8
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Plant Iridoids Terpenoids Plantaginaceae Extract Pseudolysimachion linariifolium subsp. dilatatum (Nakai & Kitag.) D. Y. Hong Extract
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Cat. No.: HY-157294B
CAS No.: 960248-81-1
Synonyms: GSK47866A
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(Rac)-GSK866 (GSK47866A) is a non-steroidal glucocorticoid receptor (GR) ligand. The crystal structure of (Rac)-GSK866 bound to the GR LBD (3E7C) can be used as a model to study the mechanism of action of ligands of the same class .
Cat. No.: HY-W010361
CAS No.: 10581-12-1
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2-Methylimidazole (Standard) is the analytical standard of 2-Methylimidazole. This product is intended for research and analytical applications. 2-Methylimidazole (2-Methyl-1H-imidazole) is a nitrogen-containing MOF ligand that serves as a laccase-mimicking activity enhancer and a morphology regulator for copper-based metal-organic frameworks. 2-Methylimidazole promotes the formation of natural laccase-like nanoenzyme structures, accelerates electron transfer and enhances catalytic activity. During hydrothermal synthesis, 2-Methylimidazole inhibits the vertical growth of crystals, thus enabling the preparation of two-dimensional nanosheet morphology .
Cat. No.: HY-168385
CAS No.: 66908-04-1
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1,3-Dimyristoyl-2-oleoylglycerol is a crystal structure of the beta1 polymorphs of mono-unsaturated triacylglycerols .
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Decacyclene is a large polycyclic aromatic hydrocarbon with a triple symmetry. Decacyclene is a three-blade molecular propeller in the solid state, and crystal structure analysis shows that the molecule has a non-planar twisted form, and the crystal is chiral, which may correspond to the enantiomers of the Decacyclene propeller. Decacyclene can be used for research in chemical synthesis and materials science .
Cat. No.: HY-120757
CAS No.: 153314-49-9
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Cat. No.: HY-120631A
CAS No.: 841302-51-0
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BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.
Cat. No.: HY-116255
CAS No.: 2059892-29-2
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MS453 is a potent and highly selective SETD8 inhibitor with an IC50 value of 804 nM. MS453 specifically modifies a cysteine residue close to the inhibitor binding site. MS453 is selective for 28 other methyltransferases. The crystal structure of MS453 reveals its binding mode to SETD8, providing an atomic-level view for the development of high-quality chemical probes for SETD8 .
Cat. No.: HY-CE00345
CAS No.: 27718-41-8
Synonyms: Coenzyme A,S-(4-hydroxybenzoate); 4-Hydroxybenzoyl-CoA; 4-Hydroxybenzoyl-coenzyme A
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(4-Hydroxybenzoyl)-CoA (Coenzyme A,S-(4-hydroxybenzoate)) is the S-(4-hydroxybenzoyl) derivative of coenzyme A. 4-Hydroxybenzoyl-CoA binds to the thioesterase active site and is hydrolyzed to CoA and 4-HBA. 4-Hydroxybenzoyl-CoA is the natural substrate of 4-Hydroxybenzoyl-CoA thioesterase and is also the dehalogenase product bound at its active site in the crystal structure .
Cat. No.: HY-189085
CAS No.: 1186659-59-5
IGF-1R-IN-6 is an IGF-1R inhibitor and a co-crystal ligand in the kinase structure of PDB 3EKK. IGF-1R-IN-6 occupies the kinase binding pocket. IGF-1R-IN-6 can be used in cancer research .
Cat. No.: HY-184616
Nanomaterials with sizes ranging from 1 to 100 nm are generally referred to as nanocrystals. The preparation of platinum nanocrystals with controllable morphology was first reported in 1996. Pt, Ag, Au, Rh, and other nanocrystals have been synthesized using various methods. Platinum has a face-centered cubic (fcc) structure, but unlike Ag, Au, and Pd, it rarely forms twins; most platinum nanocrystals are single-crystal structures. XFJ116 platinum nanoparticles were prepared via a chemical reduction method, exhibiting uniform size and good dispersibility, and can also provide platinum nanoparticles with amino and carboxyl terminator modifications.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
