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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
crystallinity
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "crystallinity" in MCE Product Catalog:
300
300 Publications Verification
Synonyms: GSK-1120212 (DMSO solvate); JTP-74057 (DMSO solvate)
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib (DMSO solvate) activates autophagy and induces apoptosis . This product is in solid form, a DMSO solvate, and a stable crystalline form.
38
38 Cited Publications
Cat. No.: HY-B1369A
CAS No.: 64221-86-9
Synonyms: N-Formimidoyl thienamycin; MK0787
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Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
38
38 Cited Publications
Cat. No.: HY-B1369
CAS No.: 74431-23-5
Synonyms: N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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3
3 Cited Publications
Synonyms: Adonitol; Adonite
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2
2 Cited Publications
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TLR7/8-IN-1 is a crystalline from of a TLR7/TLR8 inhibitor extracted from patent WO2019220390, compound 2b. TLR7/8-IN-1 can be used for the research of autoimmune disease .
1
1 Cited Publications
Cat. No.: HY-U00007A
CAS No.: 6935-63-3
Synonyms: Ba 2652 dihydrochloride; Stilbamidin dihydrochloride
Stilbamidine dihydrochloride is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.
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UCB-6876 is a TNFα inhibitor. UCB-6876 specifically binds to the asymmetric crystalline form of TNF-α trimer with a KD of 22 μM. UCB-6876 is applicable to research related to autoimmune diseases (rheumatoid arthritis and Crohn's disease) .
Cat. No.: HY-W015300
CAS No.: 505-48-6
Synonyms: Octanedioic acid
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Cat. No.: HY-W012161
CAS No.: 3061-90-3
Synonyms: L-Alanyl-L-phenylalanine; H-Ala-Phe-OH
Cat. No.: HY-W019885A
CAS No.: 7758-29-4
Synonyms: Sodium triphosphate pentabasic, 98%
Cat. No.: HY-100582R
CAS No.: 488-81-3
Synonyms: Adonitol (Standard); Adonite (Standard)
Cat. No.: HY-B1369R
CAS No.: 74431-23-5
Synonyms: N-Formimidoyl thienamycin monohydrate (Standard); MK0787 monohydrate (Standard)
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Cat. No.: HY-W744966
CAS No.: 374726-62-2
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Research Areas:
Mandipropamid is a cellulose synthase (CesA3) inhibitor and fungicide, with an IC50 of 19.8 nM against Phytophthora infestans. Mandipropamid inhibits the synthesis of crystalline cellulose on the cell surface, disrupts the cell wall structure of oomycetes, and induces germ tube tip swelling and growth arrest in Phytophthora infestans. S-Mandipropamid, an isomer of Mandipropamid, exhibits enantioselective acute toxicity to zebrafish embryos and larvae. Mandipropamid is applicable to studies related to plant infections .
Cat. No.: HY-N1446A
CAS No.: 25496-72-4
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Cat. No.: HY-W017469
CAS No.: 487-68-3
Synonyms: 2,4,6-Trimethylbenzaldehyde
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Cat. No.: HY-W250183B
CAS No.: 9005-00-9
Synonyms: Polyethylene glycol octadecyl ether (n～20)
Synonyms: 2,3-DPG pentasodium salt
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Research Areas:
2,3-Diphospho-D-glyceric acid (2,3-DPG) pentasodium salt is a hemoglobin binder and vascular calcification inhibitor that reduces the oxygen affinity of hemoglobin. 2,3-Diphospho-D-glyceric acid pentasodium salt also specifically delays the transformation of colloidal calciprotein particles into crystalline forms, thereby effectively inhibiting vascular smooth muscle cell calcification without affecting the normal formation of osteoid nodules in osteoblast-like cells. 2,3-Diphospho-D-glyceric acid pentasodium salt shows no cytotoxicity to tested cell lines and only weakly interferes with β-hematin formation mediated by glyceryl monopalmitate. 2,3-Diphospho-D-glyceric acid pentasodium salt can be used to study the pathological mechanisms of vascular calcification and malaria-related conditions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
