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crystallization

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39

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1

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11

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1

Peptides

4

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4

Natural
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Isotope-Labeled Compounds

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116285
    n-Octyl β-D-glucopyranoside
    3 Publications Verification

    		 Biochemical Assay Reagents Others
    n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .
    n-Octyl β-D-glucopyranoside
  • HY-B1620E
    Polyvinylpyrrolidone K60

    PVP K60; Polyvidone K60; Povidone K60

    		 Biochemical Assay Reagents Others
    Polyvinylpyrrolidone K60 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K60 promotes amorphous dispersion and inhibits crystallization of the drug .
    Polyvinylpyrrolidone K60
  • HY-P99665
    Insulin efsitora alfa

    LY-3209590

    		 Insulin Receptor Metabolic Disease
    Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes .
    Insulin efsitora alfa
  • HY-N2514
    α-Lactose

    α-D-Lactose

    		 Others Others
    α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .
    α-Lactose
  • HY-W129513
    Sorbitan monopalmitate

    		Biochemical Assay Reagents Others
    Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations .
    Sorbitan monopalmitate
  • HY-P99877
    Efavaleukin alfa

    AMG592

    		 Biochemical Assay Reagents Inflammation/Immunology
    Efavaleukin alfa (AMG592) is a IL-2 mutein fragment crystallizable fusion protein. Efavaleukin alfa drives the selective expansion of regulatory T cells. Efavaleukin alfa is applicable to research related to systemic lupus erythematosus .
    Efavaleukin alfa
  • HY-P99919
    Efmarodocokin alfa
    1 Publications Verification

    		 Interleukin Related Infection
    Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia .
    Efmarodocokin alfa
  • HY-P11111
    QP5

    		Drug Derivative Others
    QP5 is an Amelogenin (HY-P71627)-derived peptide. QP5 binds to hydroxyapatite and demineralized enamel surfaces, temporarily stabilizes amorphous calcium phosphate (ACP), and regulates the crystallization of hydroxyapatite. QP5 promotes remineralization of artificial enamel caries in vitro, and acts synergistically with fluoride to enhance enamel caries remineralization. QP5 can be used in studies related to enamel caries and early enamel caries .
    QP5
  • HY-W017054
    2-Amino-2-methyl-1,3-propanediol

    		Biochemical Assay Reagents Others
    2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change material with energy release and heat storage properties. 2-Amino-2-methyl-1,3-propanediol can crystallize from a supercooled solid state, release thermal energy during heating, and store thermal energy in the supercooled solid state. 2-Amino-2-methyl-1,3-propanediol can be used in the production of surfactants, vulcanization accelerators, and as a biological buffer .
    2-Amino-2-methyl-1,3-propanediol
  • HY-123622
    CYMAL-5, 98% (TLC)

    		Biochemical Assay Reagents Others
    CYMAL-5, 98% (TLC) is a cycloalkyl aliphatic saccharide. CYMAL-5, 98% (TLC) is a glycosidic surfactant (GS) with a chiral maltose polar head group and a cyclohexyl-pentyl hydrophobic tail. CYMAL-5, 98% (TLC) is a non-ionic detergent that has a tenfold lower critical micelle concentration (CMC) in comparison with OG, and has previously been used for membrane protein extraction or crystallization of membrane proteins for X-ray crystallographic studies .
    CYMAL-5, 98% (TLC)
  • HY-131591
    Digalacturonic acid

    		Endogenous Metabolite Others
    Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K .
    Digalacturonic acid
  • HY-NP193A
    Rat IgG Fc fragment

    		Fc Receptor (FcR) Inflammation/Immunology
    Rat IgG Fc fragment is a crystallizable fragment (Fc) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rat IgG Fc fragment
  • HY-116285S1
    1-O-n-Octyl-β-D-glucopyranoside-d17

    		Isotope-Labeled Compounds Others
    1-O-n-Octyl-β-D-glucopyranoside-d17 is the deuterium labeled n-Octyl β-D-glucopyranoside . n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins .
    1-O-n-Octyl-β-D-glucopyranoside-d17
  • HY-W250181
    Octyl thiomaltoside

    Octyl β-D-thiomaltopyranoside

    		 Biochemical Assay Reagents Others
    Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.
    Octyl thiomaltoside
  • HY-157657
    Cardiolipin (16:1/16:1/16:1/16:1) sodium salt

    Diphosphatidylglycerol sodium salt; 16:1 Cardiolipin sodium salt; 64:4-CL sodium salt

    		 Liposome Others
    Cardiolipin (16:1/16:1/16:1/16:1) sodium salt is an anionic phospholipid that promote hydroxyapatite crystallization and supersaturation in a calcium solution .
    Cardiolipin (16:1/16:1/16:1/16:1) sodium salt
  • HY-NP0197A
    Goat IgG Fc fragment

    		Fc Receptor (FcR) Inflammation/Immunology
    Goat IgG Fc fragment is a crystallizable fragment (Fc) of goat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Goat IgG Fc fragment
  • HY-125830
    ITIC

    		Biochemical Assay Reagents Others
    ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes. ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 °C.
    ITIC
  • HY-W040218
    MEGA-8

    N-Octanoyl-N-methylglucamine

    		 Biochemical Assay Reagents Others
    MEGA-8 (N-Octanoyl-N-methylglucamine) is a nonionic sugar-based surfactant. MEGA-8 can gently solubilize membrane proteins without easily causing their denaturation. MEGA-8 is a commonly used reagent for the extraction and study of membrane proteins in biochemistry .
    MEGA-8
  • HY-161715
    LH708

    		Others Others
    LH708 is an orally active L-cystine crystallization inhibitor with an EC50 of 59.8 nM. LH708 can be used for Cystinuria research .
    LH708
  • HY-161716
    LH1753

    		Others Others
    LH1753 is an orally active L-cystine crystallization inhibitor with an EC50 of 29.5 nM. LH1753 can be used for Cystinuria research .
    LH1753
  • HY-132930
    TCMDC-136230

    		Parasite Infection
    TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
    TCMDC-136230
  • HY-132929
    TCMDC-125431

    		Parasite Infection
    TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
    TCMDC-125431
  • HY-NP0196D
    Mouse IgG Fc fragment

    		Fc Receptor (FcR) Inflammation/Immunology
    Mouse IgG Fc fragment is a crystallizable fragment (Fc) of mouse immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Mouse IgG Fc fragment
  • HY-NP0198A
    Rabbit IgG Fc fragment

    		Fc Receptor (FcR) Inflammation/Immunology
    Rabbit IgG Fc fragment is a crystallizable fragment (Fc) of rabbit immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rabbit IgG Fc fragment
  • HY-135253
    GR122222X

    		DNA/RNA Synthesis Others
    GR122222X is a DNA gyrase B protein inhibitor related to the cyclothiidine structure, which allows the crystallization of this protein fragment for molecular replacement studies.
    GR122222X
  • HY-132931
    TCMDC-125457

    		Parasite Infection
    TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
    TCMDC-125457
  • HY-159910
    LH1513

    		Mitochondrial Metabolism Cancer
    LH1513 is a dioxalate derivative of l-lysine (HY-N0469) that inhibits CaOx crystallization with better activity than citrate and pyruvate. LH1513 has potential preventive activity in hyperoxaluria models and effectively prevents urinary CaOx crystal formation in Agxt knockout mice. AGXT-1 is a mitochondrial protein involved in metabolism .
    LH1513
  • HY-130916
    5(6)-CR6G,SE

    5(6)-CarboxyrhodaMine 6G, succinimidyl ester

    		 Biochemical Assay Reagents Others
    5(6)-CR6G,SE (5(6)-CarboxyrhodaMine 6G) is a trace fluorescent labeling reagent for fluorescence imaging of protein crystallization. 5(6)-CR6G,SE can efficiently bind to proteins to produce characteristic fluorescence under specific excitation conditions. 5(6)-CR6G,SE shows a peak absorption wavelength of approximately 525 nm and exhibits a peak fluorescence emission wavelength of around 550 nm when excited by a 530 nm green LED .
    5(6)-CR6G,SE
  • HY-121120
    Isosulfazecin

    		Antibiotic Infection
    Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .
    Isosulfazecin
  • HY-179800
    8.8 MAG

    		Others Others
    8.8 MAG acts as a detergent for crystallization.
    8.8 MAG
  • HY-179801
    8.7 MAG

    		Others Others
    8.7 MAG acts as a detergent for crystallization.
    8.7 MAG
  • HY-179783
    18:0 Dibromo MG

    		Metabolic Disease
    18:0 Dibromo MG acts as a detergent for crystallization.
    18:0 Dibromo MG
  • HY-179748
    7.7 MAG

    		Others Metabolic Disease
    7.7 MAG acts as a detergent for crystallization.
    7.7 MAG
  • HY-179783A
    18:0 Dibromo MG (S-isomer)

    		Biochemical Assay Reagents Metabolic Disease
    18:0 Dibromo MG (S-isomer) acts as a detergent for crystallization.
    18:0 Dibromo MG (S-isomer)
  • HY-179749
    7.9 MAG

    		Others Others
    7.9 MAG is a non-monoolein lipid and acts as a detergent for crystallization.
    7.9 MAG
  • HY-185217
    PPI stabilizer-1

    		Ras Cancer
    PPI stabilizer-1-1 (Compound 2) is a KRAS dimerizing agent. PPI stabilizer-1-1 dimerizes KRAS with a KD of 3.8 µM. PPI stabilizer-1-1 co-crystallizes with GCP-KRAS G12D. PPI stabilizer-1 can be used for the research of KRAS-driven cancers .
    PPI stabilizer-1
  • HY-181784
    Ac-CoA-IN-1

    		Fungal Infection
    Ac-CoA-IN-1 is an acyl-AMP phosphate analog and weak inhibitor of Candida albicans acetyl-CoA synthetase 2, with no activity against Cryptococcus neoformans acetyl-CoA synthetase 1. Ac-CoA-IN-1 crystallizes with Cryptococcus neoformans ACS1 enzyme to yield structural insight for inhibitor design. Ac-CoA-IN-1 can be used for the research of fungal infections .
    Ac-CoA-IN-1
  • HY-W414390
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%

    2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%

    		 Biochemical Assay Reagents Others
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98% (2-Cyclohexylethyl-4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranoside, 98%) is a detergent that can be used for the purification and crystallization of membrane-bound proteins in their native structure. It can self-assemble into micelles and vesicles in aqueous solution and can be used for the study of biomembrane models.
    2-Cyclohexylethyl-4-O-(α-D-glucopyranosyl)-β-D-glucopyranoside, 98%
  • HY-P991921
    TNX-1500

    		TNF Receptor Fc Receptor (FcR) Cardiovascular Disease Endocrinology
    TNX-1500 is a crystallizable fragment-modified anti-CD154 antibody. TNX-1500 contains the hu5c8 fragment antigen-binding (Fab) domain from Ruplizumab (HY-P99315) and an IgG4 Fc region engineered to reduce FcγRIIa binding. TNX-1500 has significantly weaker binding affinity to FcγRI, FcγRIIaH, FcγRIIbF, FcγRIIIaF, and FcγRIIIaV compared to hu5c8 (Kd values: 8.7 nM, 7100 nM, 4900 nM, 8000 nM, 6000 nM respectively). TNX-1500 prolongs nonhuman primate renal allograft survival, prolongs nonhuman primate cardiac allograft survival. TNX-1500 can be used for the research of allograft rejection [1] [2].
    TNX-1500

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