27 Results for "

cyclase-C

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "cyclase-C" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-17584
CAS No.: 851199-59-2
Target:  

Guanylate Cyclase

Research Areas:  

Cancer

Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
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2
2 Cited Publications
Cat. No.: HY-17584A
CAS No.: 851199-60-5
Target:  

Guanylate Cyclase

Research Areas:  

Cancer

Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
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1
1 Cited Publications
Cat. No.: HY-P71666
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Gucy2c; Guc2c; Heat-stable enterotoxin receptor; STA receptor; EC 4.6.1.2; Guanylyl cyclase C; GC-C; Intestinal guanylate cyclase
Species:  
Rat
Source:  
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Cat. No.: HY-108741
CAS No.: 467426-54-6
Purity:  99.93%
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology Cancer

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis .
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Cat. No.: HY-P3499
CAS No.: 1092457-65-2
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology

Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research .
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Cat. No.: HY-108741A
CAS No.: 1075732-84-1
Purity:  99.51%
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology Cancer

Plecanatide acetate, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide acetate activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide acetate can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of murine colitis .
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Cat. No.: HY-P3282
CAS No.: 1092457-78-7
Target:  

Guanylate Cyclase

Research Areas:  

Metabolic Disease

MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C) .
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Cat. No.: HY-P99662
CAS No.: 1514889-12-3
Synonyms: MLN0264; TAK-264
Indusatumab vedotin (MLN-0264; AKT-264) is an antibody-drug conjugate (ADC) consisting of the human anti-guanylate cyclase C (GCC) antibody linked to a microtubule-disruptor Monomethyl auristatin (HY-15162). Indusatumab vedotin has anti-proliferative effects on pancreas cancer cell lines. Indusatumab vedotin arrests cell cycle at G2/M phase, and induces apoptosis .
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Cat. No.: HY-17584R
CAS No.: 851199-59-2
Research Areas:  

Cancer

Linaclotide (Standard) is the analytical standard of Linaclotide. This product is intended for research and analytical applications. Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.
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Cat. No.: HY-P77679
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; MUCIL
Species:  
Source:  
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Cat. No.: HY-P705193
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; MUCIL
Species:  
Source:  
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Cat. No.: HY-P77680
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; MUCIL
Species:  
Source:  
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Cat. No.: HY-P704653
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
CHO
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Cat. No.: HY-P77942
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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Cat. No.: HY-P77943
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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Cat. No.: HY-P700415
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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Cat. No.: HY-P701000
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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Cat. No.: HY-P704652
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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Cat. No.: HY-P77944
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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Cat. No.: HY-P700603
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Species:  
Source:  
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