Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
60 Results for "
dATP
" in MedChemExpress (MCE) Product Catalog:
Products (60)
60 Results for "dATP" in MCE Product Catalog:
9
Research Areas:
Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.
Cat. No.: HY-158712
Purity: ≥98.0%
Synonyms: dATP trisodium
TAS1553 is a potent, orally active protein-protein interaction (PPI) inhibitor with an IC50 values of 0.0396 μM. TAS1553 inhibits DNA replication and reduces intracellular dATP pool. TAS1553 induces apoptosis. TAS1553 can be used for cancer research .
Cat. No.: HY-136648B
CAS No.: 54680-12-5
Synonyms: dATP trisodium,100 mM Solution,PCR Grade
Synonyms: SVT016426
QM31 (SVT016426), a cytoprotective agent, is a selective inhibitor of Apaf-1. QM31 inhibits the formation of the apoptosome (IC50=7.9μM), the caspase activation complex composed by Apaf-1, cytochrome c, dATP and caspase-9. QM31 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint .
0 Images
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-(3-amino-1-propyn-1-yl)-7-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-erythro-pentofuranosyl]- (TEA)
Cat. No.: HY-132143B
Cat. No.: HY-136648AR
CAS No.: 54680-12-5
Synonyms: dATP trisodium (Standard)
Cat. No.: HY-W048513
CAS No.: 60129-59-1
Cat. No.: HY-160728
CAS No.: 1048021-78-8
Synonyms: 3′-O-Azidomethyl dATP
Target:
Research Areas:
3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm -1, which determines the DNA sequences continuously .
Cat. No.: HY-D1721
Target:
Research Areas:
Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .
Cat. No.: HY-145425
CAS No.: 2771006-54-1
Research Areas:
PAIR2 is a highly selective inhibitor targeting the kinase domain of human IRE1α, with a Ki value of 8.8 nM against human IRE1α. PAIR2 fully occupies the ATP-binding site of the IRE1α kinase domain, partially antagonizes the ribonuclease activity of IRE1α, specifically inhibits regulated IRE1α-dependent decay (RIDD) and its mediated substrate cleavage, while preserving the splicing function of Xbp1 mRNA. PAIR2 also promotes the differentiation of B cells into plasma cells, blocks IRE1α-induced cell apoptosis, and restores the expression of Fgfr2 mRNA in AT2 cells. PAIR2 effectively reaches a steady-state concentration in the lung tissues of Mus musculus, and serves as an important tool for investigating the function of the IRE1α signaling pathway in diseases such as pulmonary fibrosis .
Cat. No.: HY-136648S5
Synonyms: dATP-13C10 dilithium
Cat. No.: HY-136648S1
Purity: 99.2%
Synonyms: dATP-13C10,15N5 dilithium
Cat. No.: HY-131740
CAS No.: 67460-15-5
Synonyms: C7dATP
Target:
Research Areas:
2'-Deoxytubercidin 5'-triphosphate(C7dATP) is a deoxyadenosine triphosphate (dATP) analog, which can reduce the electrophoretic mobility abnormality caused by the compression of G or A residues, and is used to improve the quality of DNA sequencing data .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
