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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
electric eel acetylcholinesterase
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "electric eel acetylcholinesterase" in MCE Product Catalog:
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Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research. Acetylcholinesterase, Electric eel can catalyze the decomposition or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetic acid and choline. The main function of Acetylcholinesterase, Electric eel is to terminate neuronal transmission and signal conduction between synapses to prevent ACh diffusion and activation of nearby receptors .
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Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively .
Cat. No.: HY-N10917
CAS No.: 688360-06-7
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Cat. No.: HY-N21824
CAS No.: 155158-70-6
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Cat. No.: HY-105853
CAS No.: 54063-52-4
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Pitofenone, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively .
Cat. No.: HY-W740798
CAS No.: 69912-75-0
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Cat. No.: HY-105853S
Cat. No.: HY-N21822
CAS No.: 62928-56-7
Synonyms: Folifine
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Cat. No.: HY-N7263
CAS No.: 134332-50-6
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Cat. No.: HY-146035
CAS No.: 2390042-05-2
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AChE-IN-14 (compound 5) is a potent cholinesterase inhibitor with IC50s of 0.46 , 0.48, and 0.44 μM for electric eel acetylcholinesterase (eeAChE), human recombinant acetylcholinesterase (hAChE), and equine serum butyrylcholinesterase (eqBuChE), respectively. AChE-IN-14 exhibits high affinity toward human H3 receptor (H3R; Ki= 159.8 nM). AChE-IN-14 can be used for the research of Alzheimer’s disease .
Cat. No.: HY-144790
CAS No.: 2764664-52-8
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AChE-IN-12 is a potent and blood-brain barrier (BBB) penetrant acetylcholinesterase (AChE) with IC50s of 0.41 μM and 1.88 μM for rat AChE and electric eel AChE. AChE-IN-12 is also a good antioxidant (ORAC = 3.3 eq), selective metal chelator and huMAO-B inhibitor (IC50 = 8.8 μM). AChE-IN-12 has remarkable inhibition of self- and Cu 2+-induced Aβ1-42 aggregation, as well as exhibits a good neuroprotective effect. AChE-IN-12 can be used for researching Alzheimer’s disease .
Cat. No.: HY-183303
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AChE-IN-116 is a selective acetylcholinesterase (AChE) inhibitor with an electric eel AChE IC50 of 1.60 μM and Ki of 1.72 μM. AChE-IN-116 exhibits weak ability to scavenge DPPH radical. AChE-IN-116 can be used for the research of Alzheimer's disease .
Cat. No.: HY-181161
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AChE-IN-107 is a selective acetylcholinesterase (AChE) inhibitor with an IC50 of 0.22 μM and a Ki of 0.207 μM. AChE-IN-107 shows no inhibitory effect on equine serum BChE at 10 μM. AChE-IN-107 exhibits mixed-type inhibition of electric eel acetylcholinesterase, binding to both free enzyme and enzyme-substrate complex. AChE-IN-107 acts as a cytotoxin, reduces cell viability in hepatocellular carcinoma HepG2 cells.AChE-IN-107 can be used for the research of alzheimer's disease .
Cat. No.: HY-N20649
CAS No.: 67068-82-0
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Cat. No.: HY-185346
CAS No.: 2365416-33-5
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AChE-IN-113 is a selective acetylcholinesterase inhibitor with a Ki value of 8.3 μM against electric eel acetylcholinesterase. AChE-IN-113 can be used for the research of Alzheimer's disease .
Cat. No.: HY-N19855
CAS No.: 69506-63-4
Synonyms: Geranicardic acid
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Cat. No.: HY-110389R
CAS No.: 1248-42-6
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Pitofenone hydrochloride (Standard) is the analytical standard of Pitofenone hydrochloride (HY-110389). This product is intended for research and analytical applications. Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively .
Cat. No.: HY-N21823
CAS No.: 220961-34-2
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Cat. No.: HY-N21596
CAS No.: 142878-03-3
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Toddalia asiatica (L.) Lam. Quinones Rutaceae Coumarins Phenylpropanoids Plants Naphthalene Quinones
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Cat. No.: HY-108723
CAS No.: 69353-21-5
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Dihydrogalanthamine hydrobromide is the hydrobromide form of 1,2-dihydrogalanthamine, which exhibits acetylcholinesterase (acetylcholinesterase, AChE) inhibitory activity. Dihydrogalanthamine hydrobromide can be used in the research of nervous system-related diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
