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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
follicle-stimulating hormone receptor
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "follicle-stimulating hormone receptor" in MCE Product Catalog:
2
Target:
Research Areas:
Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
2
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Cetrorelix (SB-75) is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix is applicable for fertility assistance research .
Cat. No.: HY-153213
CAS No.: 1421683-12-6
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Org 274179-0 is a low-molecular-weight allosteric thyrotropin receptor (TSH Receptor) antagonist with equipotent follicle-stimulating hormone receptor antagonistic activity and selectivity for the luteinizing hormone receptor. Org 274179-0 binds to the transmembrane domain of the thyrotropin receptor, stabilizes the receptor's inactive state, and blocks agonist-induced and constitutive signaling through the adenylyl cyclase/cAMP and phospholipase C pathways. Org 274179-0 can be used for research on Graves' disease and Graves' ophthalmopathy .
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FSHR agonist 1 is a high affinity and allosteric follicle stimulating hormone receptor (FSHR) agonist with a pEC50 of 7.72. FSHR agonist 1 formes extensive interactions with the TMD to directly activate FSHR .
Cat. No.: HY-160857
CAS No.: 1850256-71-1
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TOP5668 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5668 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats .
Cat. No.: HY-P0056A
CAS No.: 220810-26-4
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Cat. No.: HY-118860
CAS No.: 195962-23-3
Synonyms: Org 36286; MK-8962
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Cat. No.: HY-164764
CAS No.: 1067189-44-9
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ADX61623 is a potent follicle stimulating hormone (FSH) receptor (FSHR) negative allosteric modulator (NAM). ADX61623 shows luteinizing hormone receptor (LH-R) activity and is not active on thyroid-stimulating hormone (TSH) receptors. ADX61623 can be used for the study of estrogen dependent disease .
Cat. No.: HY-P0056
CAS No.: 76712-82-8
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Cat. No.: HY-P0009B
CAS No.: 130143-01-0
Synonyms: SB-75 diacetate
Target:
Research Areas:
Cetrorelix (SB-75) diacetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix diacetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix diacetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix diacetate is applicable for fertility assistance research .
Cat. No.: HY-160856
CAS No.: 1848981-48-5
Synonyms: TOP05300
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TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats .
Cat. No.: HY-120767
CAS No.: 1321816-57-2
Synonyms: KLH-2109 choline; OBE-2109 choline
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Linzagolix choline (KLH-2109 choline) is a non-peptide gonadotropin-releasing hormone (GnRH) antagonist with oral activity. Linzagolix choline inhibits the release of endogenous gonadotropins such as luteinizing hormone LH and follicle-stimulating hormone FSH by binding to the GnRH receptor within the pituitary gland. This inhibition results in a reduction in the production of sex hormones such as estrogen and progesterone, which in turn affects the course of sex hormone-dependent diseases. Linzagolix choline can be used in the study of sex hormone-dependent diseases such as endometriosis and uterine fibroids .
Cat. No.: HY-P72198
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FSHR; FSHRO; Prev. ODG1; FSH receptor; LGR1; FSHR1; follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; follicle stimulating hormone receptor; LRRNT Domain-Containing Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-149105
CAS No.: 487064-35-7
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FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor. FSH receptor antagonist 1 exhibits an IC50 of 28 nM on a cell line expressing the human FSH receptor. FSH receptor antagonist 1 significantly inhibits follicle growth and ovulation in an ex vivo mouse model .
Cat. No.: HY-P0009S1
Synonyms: SB-75-d10
Cat. No.: HY-134835
CAS No.: 1801551-07-4
Synonyms: Relugolix impurity 1
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GnRH antagonist 1 (Relugolix impurity 1) is a GnRH receptor antagonist that blocks the binding of gonadotropin-releasing hormone (GnRH) in the anterior pituitary, thereby inhibiting the secretion of luteinizing hormone and follicle-stimulating hormone. GnRH antagonist 1 can be used for research on endometriosis, uterine fibroids, and prostate cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
