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Isoforms Recommended:	CA IX

Results for "

hCA-IX

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Akt (1) Antibiotic (2) Apoptosis (14) Autophagy (4) Bacterial (5) Bcl-2 Family (1) c-Met/HGFR (1) Carbonic Anhydrase (98) Caspase (1) CDK (4) COX (1) DNA/RNA Synthesis (1) Endogenous Metabolite (3) ERK (1) Ferroptosis (1) HDAC (1) Hydroxycarboxylic Acid Receptor (HCAR) (1) Isotope-Labeled Compounds (1) LOX-1 (1) Mitochondrial Metabolism (2) NAMPT (1) NOD-like Receptor (NLR) (1) P-glycoprotein (1) Parasite (1) Radionuclide-Drug Conjugates (RDCs) (2) Reactive Oxygen Species (ROS) (4) Reference Standards (4) VEGFR (5) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (87) Cardiovascular Disease (5) Endocrinology (2) Infection (6) Inflammation/Immunology (3) Metabolic Disease (4) Neurological Disease (5)
Click Chemistry:	Azide (1)

104

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0782

Acetazolamide Maximum Cited Publications 13 Publications Verification	Carbonic Anhydrase Autophagy Bacterial	Cardiovascular Disease Cancer
Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC₅₀ of 30 nM for *hCA IX*. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities .

HY-B0782A

Acetazolamide sodium Maximum Cited Publications 13 Publications Verification	Carbonic Anhydrase Autophagy Bacterial	Infection Cardiovascular Disease Metabolic Disease Cancer
Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC₅₀ of 30 nM for *hCA IX*. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities .

HY-32004

Coumalic acid	Endogenous Metabolite Parasite Hydroxycarboxylic Acid Receptor (HCAR)	Infection
Coumalic acid is an inhibitor of human carbonic anhydrase (hCA) (K_I = 0.073 μM for hCA IX; K_I = 0.083 μM for hCA XII). Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavorings, fragrances and cosmetics industries, as polymer components, and pharmaceutical scaffolds. Coumalic acid displays antibronchial and antimalarial activity .

HY-B0782R

Acetazolamide (Standard) Maximum Cited Publications 13 Publications Verification	Reference Standards Carbonic Anhydrase Autophagy Bacterial	Cardiovascular Disease Cancer
Acetazolamide (Standard) is the analytical standard of Acetazolamide. This product is intended for research and analytical applications. Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC₅₀ of 30 nM for *hCA IX*. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities .

HY-W013316

Lasamide	Carbonic Anhydrase	Endocrinology
Lasamide is a potent human Carbonic Anhydrase inhibitor with K_i values of 7.54 and 2.76 nM for hCAXII and hCAIX, respectively .

HY-B0782S

Acetazolamide-d3	Carbonic Anhydrase	Cardiovascular Disease
Acetazolamide-d₃ is deuterium labeled Acetazolamide (HY-B0782). Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC₅₀ of 30 nM for hCA IX. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities.

HY-146206

HCAIX-IN-1	Carbonic Anhydrase	Cancer
HCAIX-IN-1 (compound 21e) is a potent and selective *HCAIX* inhibitor with K_Is of 694.9, 126.6, 3.3, 9.8 nM for hCA I, hCA II, hCA IX, hCA XII, respectively .

HY-W012168

4-Chloro-3-sulfamoylbenzoic acid	Carbonic Anhydrase	Metabolic Disease
4-Chloro-3-sulfamoylbenzoic acid is a weak inhibitor of human carbonic anhydrase isoforms hCA I, hCA II, hCA IV, and *hCA IX, and a synthesis intermediate for carbonic anhydrase inhibitors. 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide detected in tissues, urine, and feces of rats* and rabbits following Tripamide (HY-106570) administration. 4-Chloro-3-sulfamoylbenzoic acid can be used for the study of carbonic anhydrase inhibition and species differences in drug metabolism .

HY-W044762

5,6-Dihydro-2H-pyran-2-one	Carbonic Anhydrase	Cancer
5,6-Dihydro-2H-pyran-2-one (Compound 1) is a prodrug-type carbonic anhydrase inhibitor. 5,6-Dihydro-2H-pyran-2-one can specifically inhibit the tumor-associated subtype *hCA IX* and the cytoplasmic subtype hCA I with K_i values of 1.35 and 8.03 μM. 5,6-Dihydro-2H-pyran-2-one can be used for the research on hypoxia-related cancer .

HY-149269

COX-2-IN-30	COX Carbonic Anhydrase LOX-1	Inflammation/Immunology
COX-2-IN-30 is a benzenesulfonamide derivative, as well as an orally active and dual inhibitor of COX (IC₅₀=49 nM for COX-2, 10.4 μM for COX-1) and 5-LOX (IC₅₀=2.4 μM). COX-2-IN-30 also inhibits transmembrane *hCA IX* and hCA XII isoform with nanomolar calss K_i values. COX-2-IN-30 exhibits analgesic, anti-inflammatory, and ulcerogenic activities, and does not show acute gastric effect .

HY-155391

hCA/Wnt/β-catenin-IN-1	Carbonic Anhydrase P-glycoprotein Wnt β-catenin	Cancer
hCA/Wnt/β-catenin-IN-1 (Compd 15) is an inhibitor of *hCA* (K_i: 33.6, 24.1, 6.8 nM for hCA II, hCA IX, hCA XII). hCA/Wnt/β-catenin-IN-1 reduces P-gp activity. hCA/Wnt/β-catenin-IN-1 also inhibits Wnt/β-catenin signaling pathway. hCA/Wnt/β-catenin-IN-1 inhibits cancer cell viability, including the NCI/ADR-RES DOX-resistant cell line .

HY-147986

hCA I-IN-2	Carbonic Anhydrase	Cancer
hCA I-IN-2 (Compound 6d) is a selective *human carbonic anhydrase I (hCA* I) inhibitor with K_i** values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .

HY-147985

hCA I-IN-1	Carbonic Anhydrase	Cancer
hCA I-IN-1 (Compound 6q) is a *human carbonic anhydrase I (hCA* I) inhibitor with K_i** values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .

HY-157135

hCAIX-IN-19	Carbonic Anhydrase	Cancer
hCAIX-IN-19 is a sulfonamides inhibitor against *hCA IX* with an inhibition constant (K_I) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117) .

HY-152001

hCAIX-IN-24	Carbonic Anhydrase	Cancer
hCAIX-IN-24 is a potent and selectively *hCA IX* inhibitor with an K_I value of 32.1 nM. hCAIX-IN-24 shows anti-proliferative activity .

HY-156169

hCAIX/XII-IN-7	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-7 (compound 3e) is a potent *hCA IX* and XII inhibitor with K_is of 3.2 nM, 9.2 nM, 503.7 nM and 59 nM for hCA I, hCA II, hCA IX and hCA XII, respectively. hCAIX/XII-IN-7 has the potential for hypoxic tumors research .

HY-168030

hCAIX-IN-23	Apoptosis Ferroptosis Carbonic Anhydrase Reactive Oxygen Species (ROS) Caspase Mitochondrial Metabolism	Cancer
hCAIX-IN-23 (Compound 27) is a human carbonic anhydrase (hCA) inhibitor with K_i values of 10.4 and 8.5 nM for *hCA IX* and hCA XII, respectively. In addition to inhibiting *hCA* activity, hCAIX-IN-23 releases NO, exhibiting dual antitumor activity. hCAIX-IN-23 induces apoptosis by regulating mitochondrial caspase activity and the ferroptosis pathway (ferroptosis) through the downregulation of *hCA IX* and iron-regulatory protein expression. hCAIX-IN-23 is useful for renal cancer research .

HY-151632

hCAIX-IN-15	Carbonic Anhydrase	Cancer
hCAIX-IN-15 is a potent *hCA IX* inhibitor with a K_i value of 38.8 nM. hCAIX-IN-15 shows good broad-spectrum anticancer activity and can be used for cancer research .

HY-151630

hCAIX-IN-16	Carbonic Anhydrase	Cancer
hCAIX-IN-16 (Compound 12d) is *hCA IX* inhibitor, with K_{i values of 190.0 and 187.9 nM for hCA IX and hCA XII, respectively. hCAIX-IN-16 can arrest the cell cycle of breast cancer MDA-MB-468 in G0-G1 and S phase and induce apoptosis. hCAIX-IN-16 shows good broad-spectrum anticancer activity and can be used for cancer research .}

HY-161697

hCAIX-IN-20	Carbonic Anhydrase	Cancer
hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with the K_i of 2.7 nM. hCAIX-IN-20 plays an important role in cancer research .

HY-163414

hCAIX/XII-IN-11	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of *hCA IX* and hCA XII with a K_i value of 0.7 μM for both the isoforms. hCAIX/XII-IN-11 can be used for anticancer research .

HY-146207

HCAIX-IN-2	Carbonic Anhydrase	Cancer
HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the K_i values of 24.6 nM and 45.3 nM for *hCA IX* and hCA XII, respectively .

HY-173394

hCAIX/XII-IN-15	Carbonic Anhydrase Apoptosis	Cancer
hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of *hCA IX* and hCA XII, with K_is of 0.42 and 4.37 μM respectively. hCAIX/XII-IN-15 has pro-apoptotic effect in multiple myeloma cells .

HY-161295

hCAIX/XII-IN-10	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-10 (compound DK-8) is a carbonic anhydrase inhibitor. hCAIX/XII-IN-10 has potent inhibitory activity against tumor-associated membrane-bound isoforms *hCA IX* and XII, with K_i values of 32.5 nM and 29.2 nM .

HY-147828

hCAIX-IN-11	Carbonic Anhydrase	Cancer
hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor with K_i s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells .

HY-147827

hCAIX-IN-10	Carbonic Anhydrase	Cancer
hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with K_i s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells .

HY-150695

hCAIX/XII-IN-5	Carbonic Anhydrase Apoptosis	Cancer
hCAIX/XII-IN-5 (Coumarin 9a) a carbonic anhydrase (CA) inhibitor, and exhibits excellent hCA IX/XII selectivity (K_i=93.9 and 85.7 nM, respectively) over hCA I and hCA II. hCAIX/XII-IN-5 shows anti-proliferative activities to cancer cells. hCAIX/XII-IN-5 can delay cell cycle and induce apoptosis .

HY-162063

hCAIX/XII-IN-9	Carbonic Anhydrase	Inflammation/Immunology Cancer
hCAIX/XII-IN-9 (compound 8) is a potent carbonic anhydrase (CA) inhibitor with K_i values of 1658 nM, 184.8 nM, 8.9 nM, 64.8 nM for hCA I, hCA II, hCA IX, and hCA XII, respectively .

HY-77036R

Furagin (Standard) Furazidine (Standard); Furazidin (Standard)	Reference Standards Antibiotic Bacterial Carbonic Anhydrase	Infection Cancer
Furagin (Standard) is the analytical standard of Furagin. This product is intended for research and analytical applications. Furagin (Furazidine) is an analogue of Nitrofurantoin (HY-A0090) and has antibacterial activity. Furagin also inhibits human carbonic anhydrases (K_is: 260 and 57 nM for hCA IX and XII, respectively) .

HY-156181

hCAIX/XII-IN-8	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-8 (compound 3g) is a potent human (carbonic anhydrase) CA IX and XII inhibitor, with K_i values of 8.5 and 6.7 nM, respectively. hCAIX/XII-IN-8 shows particularly strong inhibitory activity against the tumor-associated membrane-bound isoforms, hCA IX and XII, while maintaining a high selectivity ratio over cytosolic off-target isoforms hCA I and II .

HY-179271

CA/HDAC-IN-1	Carbonic Anhydrase HDAC	Cancer
CA/HDAC-IN-1 (Compound 11) is a CA and HDAC inhibitor with K_i values of 7.4 nM, 31.0 nM, and 7.3 nM for hCA II, hCA IX, and hCA XII, respectively, and IC₅₀ values of 0.21 μM and 3.60 μM for HDAC3 and HDAC8, respectively. CA/HDAC-IN-1 has anti-cancer activity against colon cancer, breast cancer, and melanoma .

HY-150570

Carbonic anhydrase inhibitor 14	Carbonic Anhydrase CDK	Cancer
Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with K_i values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 14 can also inhibit CDK2 with an IC₅₀ of 20.3 μM. Carbonic anhydrase inhibitor 14 shows antitumor activity .

HY-101136

Dealanylascamycin AT-265	Antibiotic Carbonic Anhydrase Bacterial	Infection
Dealanylascamycin (AT-265) (Compound 2) is a nucleoside antibiotic. AT 265 is a carbonic anhydrase (CA) inhibitor, with K_i values of 167, 65.2, 234, and 143 nM for hCA I, hCA II, hCA IV, and *hCA IX* respectively. Dealanylascamycin is the active form of Ascamycin (HY-121071). Dealanylascamycin exhibits broad-spectrum antibacterial activity and is effective against pathogenic bacteria such as Xanthomonas citri (MIC = 0.4 μg/mL). Dealanylascamycin has high cytotoxicity .

HY-146254

hCAIX-IN-12	Carbonic Anhydrase Apoptosis Reactive Oxygen Species (ROS)	Cancer
hCAIX-IN-12 is a potent *hCAIX* inhibitor with IC₅₀ values of 0.74, 10.78 μM for CAIX and CAII, respectively. hCAIX-IN-12 shows antiproliferative effect and induces apoptosis. hCAIX-IN-12 increases ROS production. hCAIX-IN-12 has the potential for the research of colorectal cancer (CRC) .

HY-159128

hCAIX-IN-21	Carbonic Anhydrase	Cancer
hCAIX-IN-21 (compound 16c) is a potent *hCAIX* inhibitor with K_I values of 5.2, 3.5, 12.6, 13600 nM for hCAIX, hCA II, hCA XII, hCA I, respectively. hCAIX-IN-21 inhibits cathepsin B enzyme activity .

HY-147662

hCAIX-IN-5	Carbonic Anhydrase	Cancer
hCAIX-IN-5 (compound 6b) is a potent and selective *hCAIX* inhibitor with K_Is of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively .

HY-147665

hCAIX-IN-7	Carbonic Anhydrase	Cancer
hCAIX-IN-7 (compound 6c) is a potent and selective *hCAIX* inhibitor with K_Is of >10000, >10000, 43.0, 410.6 nM for hCAI, hCAII, hCAIV, hCAIX, respectively .

HY-147722

hCAIX-IN-8	Carbonic Anhydrase	Cancer
hCAIX-IN-8 (compound 7i) is a potent and selective *hCAIX* inhibitor with IC₅₀s of 1.99, 0.024, 1.10 μM for CAII, CAIX, CAVA respectively. hCAIX-IN-8 shows anti-proliferation activity with low toxicity. hCAIX-IN-8 decreases the epithelial to mesenchymal transitions and induces apoptosis. hCAIX-IN-8 inhibits cell migration and colonization potential .

HY-146007

hCAIX-IN-17	Carbonic Anhydrase	Cancer
hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase (hCA) inhibitor with K_i values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, *hCA IX* and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity .

HY-172178

hCAIX/XII-IN-14	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-14 (Compound 1i) is an *hCAIX/XII* inhibitor, with K_i values of hCAII, *hCAIX, and hCAXII* for 9.4 nM, 5.6 nM, and 6.3 nM, respectively .

HY-146257

hCAIX/XII-IN-2	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-2 (compound 6a) is a potent and selective *hCAIX* and hCAXIIinhibitor with K_i values of >10000, >10000, 30.0, 3.6 nM for hCAI, hCAII, hCAIX and hCAXII, respectively .

HY-146258

hCAIX/XII-IN-3	Carbonic Anhydrase	Cancer
hCAIX/XII-IN-3 (compound 6q) is a potent and selective *hCAIX* and hCAXIIinhibitor with K_i values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively .

HY-149301

hCAIX-IN-18	Carbonic Anhydrase	Cancer
hCAIX-IN-18 (compound 30) is an inhibitor of carbonic anhydrase (CA), with K_is of 3.5 nM, 9.4 nM, 43.0 nM and 8.2 nM for hCAI, hCAII, *hCAIX, hCAXII, respectively. hCAIX*-IN-18 can be used for cancer research .

HY-147663

hCAIX-IN-6	Carbonic Anhydrase	Cancer
Compounds 6b and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6k was effective on HCA XII. Compounds 6b, 14g and 6k can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action.

HY-146988

hCAIX/XII-IN-1	Carbonic Anhydrase Apoptosis	Cancer
hCAIX/XII-IN-1 is a potent CAIX/XII inhibitor with the K_I values of 0.48 µM and 0.83 µM for CAIX and CAXII, respectively. hCAIX/XII-IN-1 shows antiproliferative activity in vitro. hCAIX/XII-IN-1 induces apoptosis in MCF-7 cells .

HY-151472

hCAIX/XII-IN-6	Carbonic Anhydrase	Infection
hCAIX/XII-IN-6 is an orally active carbonic anhydrase (CA) inhibitor. hCAIX/XII-IN-6 inhibits human CA isoforms hCA I, II, IV, IX, and XII with K_i values of 6697 nM, 2950 nM, 4093 nM, 4.1 nM and 7.7 nM, respectively. hCAIX/XII-IN-6 can be used for the research of rheumatoid arthritis (RA) .

HY-151406

hCAIX-IN-13	Apoptosis	Cancer
hCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC₅₀ value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer .

HY-149329

hCAIX/VII-IN-1	Carbonic Anhydrase	Neurological Disease Cancer
hCAIX/VII-IN-1 is a selective hCA VII/IX inhibitor. hCAIX/VII-IN-1 inhibit hCAⅠ, hCAⅡ, hCAⅣ, hCAⅦ and hCAⅨ with K_i values of 336.2 nM,185.8 nM, 1055 nM, 35.6 nM and 28.0 nM, respectively. hCAIX/VII-IN-1 can be used for the research of cancer and neurological diseases .

HY-162000

hCAIX/XII-IN-13	Apoptosis	Cancer
hCAIX/XII-IN-13 is an inhibitor of human carbonic anhydrases (hCA). hCAIX/XII-IN-13 shows good inhibitory activity against the tumor-related CA subtypes IX and XII, with K_i values of 0.08 µM and 0.06 µM, respectively. Under hypoxic conditions, hCAIX/XII-IN-13 can restore the cytotoxicity of Doxorubicin (HY-15142A) on MCF-7 cells, increasing G₂/M phase cell cycle arrest and apoptosis .

HY-151633

hCAIX-IN-14	Carbonic Anhydrase	Cancer
hCAIX-IN-14 (compound 5a) is a potent inhibitor of human CA IX with a K_i value of 134.8 nM .

Cat. No.	Product Name	Target	Research Area

HY-P10761

DPI-4452	Radionuclide-Drug Conjugates (RDCs) Carbonic Anhydrase	Cancer
DPI-4452 is a CAIX-targeting cyclic peptide with a DOTA cage, and can be chelated with radionuclide for CAIX-expressing tumor PET-CT imaging and study. DPI-4452 specifically and selectively binds CAIX without interaction with an in vitro off-target receptor panel of 55 targets (IC₅₀ for recombinant hCAIX: 130 nM). Radiolabeled DPI-4452 inhibits tumor growth in HT-29 and SK-RC-52 xenograft mouse models . DPI-4452 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).

HY-P11737

IPM-N001	Radionuclide-Drug Conjugates (RDCs) Carbonic Anhydrase	Cancer
IPM-N001 is a carbonic anhydrase IX (CAIX) ligand with a K_d value of <0.0337 nM for hCAIX. When radio-conjugated with ⁶⁸Ga, IPM-N001 serves as a CAIX-targeted radionuclide tracer. [ ⁶⁸Ga]Ga-IPM-N001 exhibits excellent tumor uptake and significantly improves the tumor-to-background ratio in PET/CT imaging studies using OS-RC-2 tumor-bearing mice. IPM-N001 can be used for the research of clear cell renal cell carcinoma .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-32004

Coumalic acid	Structural Classification Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Smilacis Glabrae Rhizoma Plants Disease Research Fields Source Classification	Endogenous Metabolite Parasite Hydroxycarboxylic Acid Receptor (HCAR)
Coumalic acid is an inhibitor of human carbonic anhydrase (hCA) (K_I = 0.073 μM for hCA IX; K_I = 0.083 μM for hCA XII). Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavorings, fragrances and cosmetics industries, as polymer components, and pharmaceutical scaffolds. Coumalic acid displays antibronchial and antimalarial activity .

HY-N2682A

(E)-Dehydrodiconiferyl alcohol	Monophenols Glycine soya Classification of Application Fields Lignans Phenols Cyamopsis tetragonoloba (L.) Taub. Phenylpropanoids Plants Compositae Disease Research Fields Cancer Source Classification	Carbonic Anhydrase
(E)-Dehydrodiconiferyl alcohol behaves as good *hCA IX* and hCA XII dual inhibitors . And (E)-Dehydrodiconiferyl alcohol suppresses the NF-κB nuclear translocation in connective tissue of healing area .

HY-W015675R

4-Hydroxycyclohexanecarboxylic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Lasamide (Standard) is the analytical standard of Lasamide. This product is intended for research and analytical applications. Lasamide is a potent human Carbonic Anhydrase inhibitor with Ki values of 7.54 and 2.76 nM for hCAXII and hCAIX, respectively .

Cat. No.	Product Name	Chemical Structure

HY-B0782S

Acetazolamide-d3
Acetazolamide-d₃ is deuterium labeled Acetazolamide (HY-B0782). Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC₅₀ of 30 nM for hCA IX. Acetazolamide has diuretic, antihypertensive and anti-gonococcal activities.

HY-B0782S1

Acetazolamide-13C2,d3
Acetazolamide- ¹³C₂,d₃ is the ¹³C- and deuterium labeled Acetazolamide. Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC₅₀ of 30 nM for hCA IX . Diuretic effects .

Cat. No.	Product Name		Classification

HY-159128

hCAIX-IN-21		Azide
hCAIX-IN-21 (compound 16c) is a potent *hCAIX* inhibitor with K_I values of 5.2, 3.5, 12.6, 13600 nM for hCAIX, hCA II, hCA XII, hCA I, respectively. hCAIX-IN-21 inhibits cathepsin B enzyme activity .

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hCA-IX

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