120 Results for "

hepatitis B virus (HBV)

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "hepatitis B virus (HBV)" in MCE Product Catalog:

22
22 Publications Verification
Cat. No.: HY-B1192
CAS No.: 50-50-0
Synonyms: β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .
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17
17 Cited Publications
Cat. No.: HY-N0063
CAS No.: 65995-63-3
Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a reversible and non-competitive 3CL pro inhibitor and inhibits SARS-CoV-2 replication in vitro. Punicalagin is an anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects. Punicalagin has the potential for the research of COVID-19 .
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14
14 Cited Publications
Cat. No.: HY-100029
CAS No.: 298708-81-3
Purity:  99.24%
Target:  

HBV

Research Areas:  

Infection

BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
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4
4 Cited Publications
Cat. No.: HY-N0699
CAS No.: 2034-69-7
Synonyms: Dephnoretin; Thymelol
Daphnoretin (Dephnoretin; Thymelol) is a protein kinase C (PKC) activator that inhibits the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and exhibits antiviral activity. Daphnoretin exerts its antitumor effects by inhibiting the activation of the PI3K/AKT signaling pathway and triggers the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and activation of the NLRP3 inflammasome. Daphnoretin regulates the differentiation and maturation of dendritic cells, inhibits their immunostimulatory function by downregulating the phosphorylation level of JNK, and thus exerts a protective effect in skin graft rejection .
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3
3 Cited Publications
Cat. No.: HY-N0639
CAS No.: 65995-64-4
Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity .
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2
2 Cited Publications
Cat. No.: HY-109137
CAS No.: 2004677-13-6
Purity:  98.18%
Synonyms: GS-9688
Research Areas:  

Infection

Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection .
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2
2 Cited Publications
Cat. No.: HY-112564
CAS No.: 1572510-42-9
Purity:  99.94%
Target:  

HBV

Research Areas:  

Infection

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).
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2
2 Cited Publications
Cat. No.: HY-N6939
CAS No.: 82508-31-4
Pseudolaric Acid B is an orally active diterpene acid. Pseudolaric Acid B has anti-fungal, anti-fertility, anti-angiogenesis and anticancer activity, and can induce tumor cell apoptosis and autophagy. In addition, Pseudolaric Acid B can inhibit the secretion of hepatitis B virus (HBV) and has immunosuppressive effect, selectively inhibiting the proliferation of T lymphocytes and the production of IL-2 .
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2
2 Cited Publications
Cat. No.: HY-109195
CAS No.: 2090064-66-5
Purity:  99.73%
Synonyms: ABI-H0731
Target:  

HBV

Research Areas:  

Infection Inflammation/Immunology

Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM .
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2
2 Cited Publications
Cat. No.: HY-100028
CAS No.: 211364-06-6
Purity:  98.39%
Target:  

HBV DNA/RNA Synthesis

Research Areas:  

Infection Cancer

AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells .
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2
2 Cited Publications
Cat. No.: HY-100029A
CAS No.: 298708-79-9
Purity:  98.92%
Target:  

HBV

Research Areas:  

Infection

BAY 41-4109 racemate is the racemate of BAY 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
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2
2 Cited Publications
Cat. No.: HY-N8107
CAS No.: 34446-06-5
Matairesinol monoglucoside is a STING activator. Matairesinol monoglucoside modulates the STING-TBK1-IRF3 signaling axis, promotes STING transcriptional expression, increases TBK1 and IRF3 phosphorylation. Matairesinol monoglucoside induces IFN-α and IFN-β production, reduces HBV DNA, HBsAg, and HBeAg expression. Matairesinol monoglucoside can be used for the research of hepatitis b virus (hbv) infection .
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1
1 Cited Publications
Cat. No.: HY-B0017
CAS No.: 3424-98-4
Synonyms: Epavudine; L-Thymidine; NV 02B
Target:  

HBV

Research Areas:  

Infection

Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication .
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1
1 Cited Publications
Cat. No.: HY-148560
CAS No.: 2919019-72-8
Purity:  98.87%
Target:  

HBV DNA/RNA Synthesis

Research Areas:  

Infection

ccc_R08 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection .
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1
1 Cited Publications
Cat. No.: HY-19447
CAS No.: 441785-25-7
Synonyms: LB80331
Target:  

HBV

Research Areas:  

Infection

Besifovir (LB80331), a parent agent converted by LB80380 (HY-19447A), further metabolizes to its active form, LB80317 (HY-106235). Besifovir is an orally active, novel antiviral agent against hepatitis B virus (HBV) .
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1
1 Cited Publications
Cat. No.: HY-P74354
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Capsid protein; Core antigen; C protein; HBcAg; hepatitis B virus (HBV)(ayw/France/Tiollais/1979)
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-118122
CAS No.: 69123-98-4
Purity:  99.91%
Synonyms: FIAU; DRG-0098; NSC 678514
Fialuridine (FIAU), a nucleoside analog, is a HSV-1 and HSV-2 inhibitor with Kis of 0.14 μM and 0.95 μM, respectively. Fialuridine shows anti-orthopoxvirus and anti-hepatitis B virus (HBV) activities. Fialuridine inhibits duck HBV DNA replication with IC50 values of 0.075 μM and 156 μM in human hepatoma cells and in chicken liver cells, respectively .
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Cat. No.: HY-147255
CAS No.: 2137847-19-7
Purity:  98.40%
Synonyms: ZM-H1505R
Target:  

HBV

Research Areas:  

Infection

Canocapavir (ZM-H1505R) is an orally active HBV core protein-targeting antiviral agent. Canocapavir binds to the hydrophobic pocket at the dimer-dimer interface of HBV core protein (HBc), stimulating intracellular accumulation of nonfunctional HBV capsids, disrupting viral replication. Canocapavir interferes with the interaction between HBc and HBV large surface protein, resulting in diminished
production of empty virionsis. Canocapavir can be used for the research of hepatitis B virus (HBV) infection .
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Cat. No.: HY-P990015
CAS No.: 2645440-65-7
Synonyms: VIR-3434

Target:  

HBV

Research Areas:  

Infection

Tobevibart (VIR-3434) is a human IgG1 lambda monoclonal antibody against hepatitis B virus (HBV) surface antigen (HBsAg). Tobevibart shows potent neutralization against HBsAg from all HBV genotypes in vitro and inhibits viral entry of HBV and hepatitis delta virus (HDV). Recommend Isotype Controls: Human IgG1 lambda2, Isotype Control (HY-P990096) .
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Cat. No.: HY-W074930
CAS No.: 147127-19-3
Synonyms: (S)-GS 1278; (S)-PMPA; (S)-TDF
Target:  

HIV HBV

Research Areas:  

Infection

(S)-Tenofovir is the less active S-enantiomer of Tenofovir (HY-13910). Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV). (S)-Tenofovir has low activity to Orf virus. (S)-Tenofovir can be used for research on contagious pustular dermatitis .
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