1. Anti-infection
  2. HBV
  3. Besifovir

Besifovir (Synonyms: LB80331)

Cat. No.: HY-19447
Handling Instructions

Besifovir (LB80331), a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV) .

For research use only. We do not sell to patients.

Besifovir Chemical Structure

Besifovir Chemical Structure

CAS No. : 441785-25-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 187 In-stock
Estimated Time of Arrival: December 31
5 mg USD 170 In-stock
Estimated Time of Arrival: December 31
10 mg USD 270 In-stock
Estimated Time of Arrival: December 31
50 mg USD 820 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1120 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Besifovir:

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Description

Besifovir (LB80331), a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV) [1][2].

Molecular Weight

299.22

Formula

C₁₀H₁₄N₅O₄P

CAS No.

441785-25-7

SMILES

NC1=NC=C2N=CN(CC3(OCP(O)(O)=O)CC3)C2=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (835.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3420 mL 16.7101 mL 33.4202 mL
5 mM 0.6684 mL 3.3420 mL 6.6840 mL
10 mM 0.3342 mL 1.6710 mL 3.3420 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (6.95 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (6.95 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.95 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BesifovirLB80331LB 80331LB-80331HBVHepatitis B virusInhibitorinhibitorinhibit

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Product name:
Besifovir
Cat. No.:
HY-19447
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