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iodine

" in MedChemExpress (MCE) Product Catalog:

54

Inhibitors & Agonists

4

Fluorescent Dyes

11

Biochemical Assay Reagents

1

Inhibitory Antibodies

4

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1

Isotope-Labeled Compounds

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1620
    Polyvinylpyrrolidone K30

    PVP K30; Polyvidone K30; Povidone K30

    		 Environmental Pollutants Biochemical Assay Reagents Infection
    Polyvinylpyrrolidone K30 is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.
    Polyvinylpyrrolidone K30
  • HY-107903
    Thyroglobulin

    Thyroglobulin from bovine

    		 Biochemical Assay Reagents Cancer
    Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle. Thyroglobulin activates Akt kinase activity in FRTL-5 thyroid cell .
    Thyroglobulin
  • HY-142870
    ZY-444

    		Pyruvate Carboxylase (PC) Apoptosis β-catenin ERK Wnt Cancer
    ZY-444 is an anti-cancer agent, targeting pyruvate carboxylase (PC). ZY-444 suppresses the Wnt/β-catenin/Snail signaling pathway by blocking nuclear translocation of β-catenin. ZY-444 selectively inhibits proliferation, migration, and invasion and induces apoptosis in cancer cells. ZY-444 exhibits potent anti-tumor in cancer mouse models. ZY-444 can be used for the study of breast cancer, lung cancer (NSCLC), prostate cancer and iodine-refractory thyroid cancer .
    ZY-444
  • HY-B1426
    Iodixanol
    3 Publications Verification

    		 Biochemical Assay Reagents Cancer
    Iodixanol is an iodine-containing non-ionic radiocontrast agent .
    Iodixanol
  • HY-B1770
    Sodium Iodide,99%

    		Environmental Pollutants Biochemical Assay Reagents Cardiovascular Disease Endocrinology
    Sodium Iodide is a compound composed of sodium ions and iodine ions. Sodium Iodide scavenges hydrogen peroxide. Sodium Iodide maintains the level of thyroid hormone T3 through its iodine component. Sodium Iodide protects tissues from oxidative damage and regulates thyroid homeostasis. Sodium Iodide relieves acute myocardial infarction .
    Sodium Iodide,99%
  • HY-B1620H
    Polyvinylpyrrolidone K90

    PVP K90; Polyvidone K90; Povidone K90

    		 Environmental Pollutants Biochemical Assay Reagents Infection
    Polyvinylpyrrolidone K90 can be used to prepare drug delivery systems, such as electrospun nanofibrous membranes. Polyvinylpyrrolidone K90 is widely used in human and veterinary medicine as an effective wound healing promoter and disinfectant when combined with iodine and other compounds. In addition, Polyvinylpyrrolidone K90 is also used to stabilize nanosuspensions, interact with the surface of drug crystals, and remain bound to the surface after drying .
    Polyvinylpyrrolidone K90
  • HY-B2234
    Povidone iodine
    2 Publications Verification

    iodopovidone

    		 Environmental Pollutants Bacterial Infection
    Povidone iodine (iodopovidone) displays excellent antibacterial activity which can against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively.
    Povidone iodine
  • HY-D0826
    Cy2-SE (iodine)

    Cyanine2 Succinimidyl Ester (iodine)

    		 Fluorescent Dye Others
    Cy2-SE iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
    Cy2-SE (iodine)
  • HY-108775A
    Sodium thiosulfate (99%, water≤1.0%)

    Sodium hyposulfite (99%, water≤1.0%)

    		 Environmental Pollutants Biochemical Assay Reagents COX Interleukin Related NF-κB β-catenin GSK-3 Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Sodium thiosulfate is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease .
    Sodium thiosulfate (99%, water≤1.0%)
  • HY-W016153
    2-Bromo-4-methylphenol

    		Biochemical Assay Reagents Bacterial Fungal Infection
    2-Bromo-4-methylphenol is a versatile compound. 2-Bromo-4-methylphenol produces an iodine-like odor in reverse osmosis water and red wine matrices. 2-Bromo-4-methylphenol exhibits antibacterial properties and effectively inhibits the growth of bacteria and fungal. 2-Bromo-4-methylphenol is an important intermediate for a variety of organic compounds .
    2-Bromo-4-methylphenol
  • HY-B1362
    Iopromide
    2 Publications Verification

    		 Biochemical Assay Reagents Cardiovascular Disease
    Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.
    Iopromide
  • HY-W094695
    Starch soluble

    		Biochemical Assay Reagents Others
    Starch soluble is a biodegradable, highly biocompatible hydrophilic biopolymer nanocarrier. Starch soluble forms complexes with iodine, acts on multiple bacterial targets, and improves the storage stability of iodine. Starch soluble enhances the solubility and dissolution rate of Gefitinib (HY-50895). Starch soluble can be used as a nanocarrier for relevant studies .
    Starch soluble
  • HY-W075603
    2,6-Diiodo-BODIPY 493/503

    2,6-Diiodo-Pyrromethene 546

    		 Fluorescent Dye Others
    2,6-Diiodo-BODIPY 493/503 is an F-Bodipy fluorescent dye with diiodo substitution at the (pyrrole) 2,6 position. 2,6-Diiodo-BODIPY 493/503 has a pyrrole iodine substituent that turns it red .
    2,6-Diiodo-BODIPY 493/503
  • HY-40145
    1-Boc-3-iodoazetidine

    		Drug Intermediate Others
    1-Boc-3-iodoazetidine acts as a bifunctional additive for lithium-oxygen (Li-O2) batteries and can be used to enhance the performance of Li-O2 batteries. 1-Boc-3-iodoazetidine is applied in the synthesis of C3-functionalized azetidines and C2-functionalized azetidines via a lithium/iodine exchange or β-elimination/lithiation reaction sequence .
    1-Boc-3-iodoazetidine
  • HY-W145520
    Amylopectin

    		Biochemical Assay Reagents Others
    Amylopectin is a branched glucan polymer and one of the two principal components of starch, found in botanical sources including corn, amaranth, and potato .
    Amylopectin
  • HY-N10348
    Progoitrin

    		Others Drug Derivative Endocrinology
    Progoitrin is a sulfur-containing glucosinolate, as well as a naturally occurring orally active thioglycoside. Progoitrin acts as a hepatotoxin and antithyroid agent. Progoitrin is quantitatively converted to goitrin in vivo, including via a gastrointestinal hydrolysis pathway that does not require exogenous myrosinase, thereby blocking the organification of iodine in the thyroid gland and inhibiting the uptake and accumulation of radioactive iodine. Progoitrin can be used in studies related to Graves' disease .
    Progoitrin
  • HY-P99566
    Tenatumomab

    ST2146

    		 Transmembrane Glycoprotein Cancer
    Tenatumomab (ST2146) is a murine monoclonal antibody against tenascin-C. And tenascin-C, the large extracellular glycoprotein, is overexpressed in cancer. Tenatumomab has been used for Pretargeted Antibody Guided Radioimmunoresearch (PAGRIT), and delivering radionuclides to tumors via PAGRIT and direct 131Iodine labeling approach .
    Tenatumomab
  • HY-D1054
    Cy2 (iodine)

    Cyanine2 (iodine)

    		 Fluorescent Dye Others
    Cy2 iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
    Cy2 (iodine)
  • HY-B1796
    Thymol iodide

    		Fungal Infection
    Thymol iodide is an iodine derivative of thymol, serving as a mild preservative and fungicide. Thymol iodide is commonly used as an iodine source in the intensive culture of rotifers. Thymol iodide effectively enables Brachionus "Cayman" rotifers to reach iodine levels similar to those of copepods, and maintains a high iodine content during storage. After 28 days of intrapleural injection of Thymol iodide, it does not enhance the efficacy of inducing pleurodesis in rabbits, nor does it improve the efficacy of talc slurry pleurodesis .
    Thymol iodide
  • HY-149132
    Dendrogenin A

    DDA

    		 LXR Cancer
    Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase .
    Dendrogenin A
  • HY-114918
    MS438

    		TSH Receptor Endocrinology
    MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice .
    MS438
  • HY-114994
    MS437

    		TSH Receptor Endocrinology
    MS437 is a potent TSH receptor (TSHR) stimulator with an EC50 value of 13x10 -8 M. MS437 shows potent activation of Gsα, Gαq and Gα12 and up-regulation of thyroglobulin (Tg), sodium iodine symporter (NIS) and TSHR gene expressions .
    MS437
  • HY-W025438
    5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine

    		Nucleoside Antimetabolite/Analog Drug Intermediate Others
    5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a 2'-O-methyluridine derivative bearing a 5'-O-(4,4'-dimethoxytrityl) protecting group.5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine serves as a starting material for synthesis of a conformationally rigid cyclic uridylic acid derivative .
    5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine
  • HY-W002668
    5-Bromo-2-iodopyridine

    		Biochemical Assay Reagents Drug Intermediate Others
    5-Bromo-2-iodopyridine is a pyridine derivative containing bromine and iodine, which can be used in the synthesis of other active compounds, such as Lonafarnib .
    5-Bromo-2-iodopyridine
  • HY-N0224A
    Goitrin

    (S)-Goitrin; L-5-Vinyl-2-thiooxazolidone

    		 Influenza Virus Metabolic Disease
    Goitrin ((S)-Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity .
    Goitrin
  • HY-W053842
    tert-Butyl 3-iodopropylcarbamate

    		Biochemical Assay Reagents Others
    tert-Butyl 3-iodopropylcarbamate is a compound with a t-butyl and a terminal iodine. The iodine (I) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
    tert-Butyl 3-iodopropylcarbamate
  • HY-117953
    RU 59063

    		Prostaglandin Receptor Endocrinology
    RU 59063 is an N-substituted arylthiohydantoin compound with antiandrogenic activity and high relative binding affinity for the rat androgen receptor. RU 59063 is a nonsteroidal androgen receptor that functions as a radioactive AR radioprobe (Ki: 0.71 nM, rAR) when its trifluoromethyl group is replaced by a similar hydrophobic iodine atom .
    RU 59063
  • HY-W011079
    5-Iodouridine
    1 Publications Verification

    		 Nucleoside Antimetabolite/Analog Infection Cancer
    5-Iodouridine is an iodine-containing pyrimidine nucleoside analog. 5-Iodouridine inhibits dihydroorotase with a Ki value of 340 µM. 5-Iodouridine significantly enhances the cell-killing effect of gamma irradiation. 5-Iodouridine can be used in the research of HSV-1 infection and leukemia .
    5-Iodouridine
  • HY-34619
    [Hydroxy(tosyloxy)iodo]benzene
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    [Hydroxy(tosyloxy)iodo]benzene is a versatile reagent for the mild oxidation of aryl iodides at the iodine atom by ligand transfer. [Hydroxy(tosyloxy)iodo]benzene is an effective reagent for the one-step conversion of ketones to the corresponding α-tosyloxy ketones. [Hydroxy(tosyloxy)iodo]benzene is also a Bronsted acid and is expected to catalyze the enolization of ketones .
    [Hydroxy(tosyloxy)iodo]benzene
  • HY-130982
    Lenalidomide-PEG3-iodine

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Lenalidomide-PEG3-iodine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Lenalidomide based cereblon ligand and a 3-unit PEG linker. Lenalidomide-PEG3-iodine can be used in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM .
    Lenalidomide-PEG3-iodine
  • HY-W442078
    Iodine-C3-O-C3-PEG-Boc

    		PROTAC Linkers Cancer
    Iodine-C3-O-C3-PEG-Boc is a PROTAC linker that can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961) .
    Iodine-C3-O-C3-PEG-Boc
  • HY-133846
    Iodothiouracil

    		Thyroid Hormone Receptor Cancer
    Iodothiouracil exhibits high selectivity for melanoma, remains stable in the melanin in melanoma cells, and localizes remote secondary metastases of melanoma. Iodothiouracil can be used for melanoma imaging when labeled with iodine-123, and can be used for radiation therapy when labeled with iodine-131 .
    Iodothiouracil
  • HY-W460133
    tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate

    		Biochemical Assay Reagents Others
    tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate is a PEG linker containing a Boc protected amine and an iodine group. The protected amine can be deprotected under mild acidic conditions. Iodine (I) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
    tert-Butyl (2-(2-(2-iodoethoxy)ethoxy)ethyl)carbamate
  • HY-W586331
    Thalidomide-iodo

    		Ligands for E3 Ligase Cancer
    Thalidomide-iodo is an iodinated E3 ligase activator. Thalidomide-iodo can be used for further derivitization by substitution of iodine.
    Thalidomide-iodo
  • HY-B1362S
    Iopromide-d3

    		Isotope-Labeled Compounds Cardiovascular Disease
    Iopromide-d3 is the deuterium labeled Iopromide. Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.
    Iopromide-d3
  • HY-B1362R
    Iopromide (Standard)

    		Biochemical Assay Reagents Reference Standards Cardiovascular Disease
    Iopromide (Standard) is the analytical standard of Iopromide. This product is intended for research and analytical applications. Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration.
    Iopromide (Standard)
  • HY-W076313
    2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione
    1 Publications Verification

    		 Ligands for E3 Ligase Cancer
    2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione is a derivative of Thalidomide with an iodine atom on the benzyl ring
    2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione
  • HY-131556
    4-Iodoamphetamine hydrochloride

    p-Iodoamphetamine hydrochloride

    		 5-HT Receptor Neurological Disease
    4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. 4-Iodoamphetamine hydrochloride selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes.
    4-Iodoamphetamine hydrochloride
  • HY-B1292R
    Iodipamide (Standard)

    Adipiodone (Standard)

    		 Reference Standards Others
    Iodipamide (Standard) is the analytical standard of Iodipamide. This product is intended for research and analytical applications. Iodipamide is an iodine-based contrast agent, mainly used for X-ray imaging, particularly for gallbladder and bile duct imaging [1] .
    Iodipamide (Standard)
  • HY-155446
    di-DTPA-LTL

    		Hapten Inflammation/Immunology Cancer
    di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients .
    di-DTPA-LTL
  • HY-W441271
    Deoxy-thalidomide-5-iodine

    		Ligands for E3 Ligase Cancer
    Deoxy-thalidomide-5-iodine is a Thalidomide analog that can be useful in PROTAC research.
    Deoxy-thalidomide-5-iodine
  • HY-14998
    Halofenate

    MK 185

    		 β-catenin PPAR Wnt Endocrinology
    Halofenate, structurally akin to clofibrate, was evaluated in hypertriglyceridemic patients over 6-week periods in a controlled, double-blind crossover trial. It effectively reduced serum triglycerides by 50%, with minimal impact on serum cholesterol levels. Additionally, it lowered serum uric acid by 30% and exhibited uricosuric effects independent of glomerular filtration rate. Halofenate was associated with a significant increase in plasma thyroxine (T4), accompanied by a decrease in protein-bound iodine and T4 by column. In vitro studies confirmed its ability to displace T4 from thyroid-binding proteins, suggesting a thyroxine-displacing effect, which could influence thyroid function in vivo .
    Halofenate
  • HY-169395
    (S,R,S)-AHPC-CO-PEG-C2-iodine

    		E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-CO-PEG-C2-iodine is an E3 ligase (VHL) ligand-linker conjugate, and can be used for synthesis of PROTACs, such as PROTAC FAK degrader 1 (HY-119932)
    (S,R,S)-AHPC-CO-PEG-C2-iodine
  • HY-D3448
    8-Anthracene-BODIPY 505/515-di(iodine)

    		Fluorescent Dye Others
    8-Anthracene-BODIPY 505/515-di iodine (BDP-1) is an iodine-substituted BODIPY derivative and monomer for synthesis of conjugated porous polymer CPP-1. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high (Ex/Em = 505/515 nm) .
    8-Anthracene-BODIPY 505/515-di(iodine)
  • HY-W348170
    tert-Butyl((5-iodopentyl)oxy)dimethylsilane

    		Biochemical Assay Reagents Others
    tert-Butyl((5-iodopentyl)oxy)dimethylsilane is a silane compound with a terminal iodine group. The trimethylsilane is commonly used for surface modifications. The iodine (I) is a very good leaving group for nucleophilic substitution reactions.
    tert-Butyl((5-iodopentyl)oxy)dimethylsilane
  • HY-W248726
    tert-Butyl (6-iodohexyl)carbamate

    		Biochemical Assay Reagents Others
    tert-Butyl (6-iodohexyl)carbamate is a six carbon linker containing an iodine group and a t-butyl ester. The iodine (I) acts as a good leaving group for nucleophilic substitution reactions. The t-butyl ester groups can be deprotected under acidic conditions.
    tert-Butyl (6-iodohexyl)carbamate
  • HY-W092078
    tert-Butyl (4-iodobutyl)carbamate

    		Biochemical Assay Reagents Others
    tert-Butyl (4-iodobutyl)carbamate is a four carbon linker containing a Boc-protected amino group and an iodine group. The Boc group can be deprotected under mild acidic conditions to form the free amine. Iodine (I) is a very good leaving group for nucleophilic substitution reactions.
    tert-Butyl (4-iodobutyl)carbamate
  • HY-W587533
    Cyclic iodixanol

    		Drug Intermediate Others
    Cyclic iodixanol is a impurity of Iodixanol (HY-B1426). Iodixanol is an iodine-containing non-ionic radiocontrast agent.
    Cyclic iodixanol
  • HY-B1292B
    Iodipamide meglumine

    Adipiodone meglumine

    		 Biochemical Assay Reagents Others
    Iodipamide (Adipiodone) meglumine is an iodine-based contrast agent, mainly used for X-ray imaging, particularly for gallbladder and bile duct imaging.
    Iodipamide meglumine
  • HY-W041657
    5-Iodopicolinic acid

    5-Iodopyridine-2-carboxylic acid

    		 Drug Intermediate Others
    5-Iodopicolinic acid (5-Iodopyridine-2-carboxylic acid) is an organic iodine compound. As an intermediate, 5-Iodopicolinic acid can be used in the synthesis of other active compounds .
    5-Iodopicolinic acid

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