14 Results for "

isoindolinone

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "isoindolinone" in MCE Product Catalog:

Cat. No.: HY-W004767
CAS No.: 480-91-1
Isoindolinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-N15388
CAS No.: 126654-52-2
Hericenone A is an isoindolinone found in the fruiting bodies of Hericium erinaceus. Hericenone A exerts cytotoxic activity against cancer cells. Hericenone A can be used for the research of cancer, such as metastatic human hepatocellular carcinoma .
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Cat. No.: HY-138790
CAS No.: 2927334-86-7
Purity:  99.52%
Research Areas:  

Cancer

Glutarimide-Isoindolinone-NH-PEG4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology .
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Cat. No.: HY-103407A
CAS No.: 1782532-06-2
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease Cancer

PD 168568 dihydrochloride is a orally active and potent dopamine receptor D4 (DRD4) antagonist. PD 168568 dihydrochloride contains an isoindolinone and is selective for the D4 receptor versus D2 and D3, with Ki values of 8.8, 1842, and 2682 nM, respectively. PD 168568 dihydrochloride can be used for glioblastoma (GBM) research .
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Cat. No.: HY-169575
CAS No.: 1606996-12-6
PARP1-IN-36 (compound 11) is a 4-carboxamido-isoindolinone derivative and a selective PARP-1 inhibitor with a Kd < 0.01 μM. PARP1-IN-36 can be utilized in cancer, cardiovascular diseases, nervous system injury and inflammation research .
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Cat. No.: HY-103407
CAS No.: 210688-56-5
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease Cancer

PD 168568 is a orally active and potent dopamine receptor D4 (DRD4) antagonist. PD 168568 contains an isoindolinone and is selective for the D4 receptor versus D2 and D3, with Ki values of 8.8, 1842, and 2682 nM, respectively. PD 168568 can be used for glioblastoma (GBM) research .
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Cat. No.: HY-W745874
3-(4-Chlorophenyl)-1-isoindolinone-d4 is the deuterium labeled 3-(4-Chlorophenyl)isoindolin-1-one (HY-W600173).
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Cat. No.: HY-138791
CAS No.: 2803819-65-8
Purity:  99.12%
Research Areas:  

Cancer

Glutarimide-Isoindolinone-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology .
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Cat. No.: HY-138792
CAS No.: 2803827-03-2
Purity:  98.51%
Research Areas:  

Cancer

Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology .
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Cat. No.: HY-147617
CAS No.: 2361378-89-2
Target:  

c-Fms

Research Areas:  

Cancer

CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1) .
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Cat. No.: HY-N21648
CAS No.: 1629208-29-2
Hericerin A is an isoindolinone derivative and a selective cytotoxic agent. Hericerin A is isolated from Hericium erinaceus cultured on brown rice. Hericerin A downregulates the phosphorylation of AKT and downregulates c-Myc oncoprotein levels downstream of p-AKT inactivation. Hericerin A induces Apoptosis. Hericerin A exhibits anticancer activity against leukemia. Hericerin A is used in research on acute promyelocytic leukemia, breast cancer, and Helicobacter pylori infection .
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Cat. No.: HY-N21647
CAS No.: 870193-55-8
Erinacerin B is an isoindolinone skeleton compound. Erinacerin B is present in the mycelia and fruiting bodies of Hericium erinaceus. Erinacerin B inhibits NF-κB (p65 subunit) and AP-1 (c-Jun subunit). Erinacerin B inhibits LPS-induced nitric oxide and Prostaglandin E2 (HY-101952) production. Erinacerin B attenuates neuroinflammation. Erinacerin B is used in research on neurodegenerative and inflammatory diseases .
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Cat. No.: HY-P4948
CAS No.: 1926163-49-6
Research Areas:  

Others

Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
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