lipoamide

By Targets:	CXCR (2) Endogenous Metabolite (2) Insulin Receptor (1) Melanocortin Receptor (1) Neuropeptide Y Receptor (2) NO Synthase (1) Parasite (1) PROTAC Linkers (2) Trk Receptor (1)
By Research Areas:	Cancer (5) Metabolic Disease (2) Neurological Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1142

*Lipoamide* 5+ Cited Publications (±)-α-lipoamide; DL-lipoamide; DL-6,8-Thioctamide	NO Synthase	Others
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P2800A

Diaphorase, clostridium sp.	Endogenous Metabolite	Metabolic Disease
Diaphorase, Clostridium sp. is a diaphorase derived from Clostridium sp. As a flavin-containing NAD (P) H dehydrogenase, Diaphorase, Clostridium sp. uses NADH as an electron donor to reduce artificial dyes such as DCPIP and NBT, and participates in energy metabolism .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-141338

Lipoamide-PEG3-Mal	PROTAC Linkers	Cancer
Lipoamide-PEG3-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-141339

Lipoamide-PEG11-Mal	PROTAC Linkers	Cancer
Lipoamide-PEG11-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-E70340

Lipoamide dehydrogenase, porcine	Endogenous Metabolite	Others
Lipoamide dehydrogenase, porcine is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-N19829

Lipoamide B	Others	Others
Lipoamide B is a lipoic acid amide present in marine Bacillus pumilus (SP21) .

HY-N19828

Lipoamide A	Others	Others
Lipoamide A is a natural lipoic acid product isolated from marine Bacillus pumilus (SP21) .

HY-P11480

TrkA/NGF-IN-1	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Cat. No.	Product Name	Target	Research Area

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-P11480

TrkA/NGF-IN-1	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1142

*Lipoamide* 5+ Cited Publications (±)-α-lipoamide; DL-lipoamide; DL-6,8-Thioctamide	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	NO Synthase
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-N19829

Lipoamide B	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Others
Lipoamide B is a lipoic acid amide present in marine Bacillus pumilus (SP21) .

HY-N19828

Lipoamide A	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Others
Lipoamide A is a natural lipoic acid product isolated from marine Bacillus pumilus (SP21) .

Species:	Human (4)
Tag:	His (2) Strep (1) Tag Free (1) GST (1)
Source:	Sf9 insect cells (2) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P74207

	DBT Protein, Human (sf9, His) lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; BCKAD-E2; DBT	Human	Sf9 insect cells
	DBT proteins are components of the branched-chain α-keto dehydrogenase complex, which catalyzes the conversion of α-keto acids into acyl-CoA and CO(2). This complex includes branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2), and lipoamide dehydrogenase (E3). DBT Protein, Human (sf9, His) is the recombinant human-derived DBT protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P702948

	BCKDK Protein, Human (sf9, GST) Branched-chain alpha-ketoacid dehydrogenase kinase; BCKDH kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase; mitochondrial	Human	Sf9 insect cells
	BCKDK Protein, Human (sf9, GST) is the recombinant human-derived BCKDK, expressed by Sf9 insect cells , with GST labeled tag.

HY-P703609

	BCKDK Protein, Human Branched-chain alpha-ketoacid dehydrogenase kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; 2.7.11.4; BCKDK; Homo sapiens; Human; Kinase; Transferase; 2.7.11.1	Human	E. coli
	BCKDK Protein, Human is the recombinant human-derived BCKDK, expressed by E. coli, with tag free labeled tag.

HY-P703610

	BCKDK Protein, Human (His, Strep) Branched-chain alpha-ketoacid dehydrogenase kinase; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; 2.7.11.4; BCKDK; Homo sapiens; Human; Kinase; Transferase; 2.7.11.1	Human	E. coli
	BCKDK Protein, Human (His, Strep) is the recombinant human-derived BCKDK, expressed by E. coli, with Strep, His labeled tag.

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Host:	Mouse (3) Rabbit (6)
Reactivity:	Human (9) mouse (1) rat (1) Rat (5) Mouse (8)
Application:	WB IHC-P (1) IHC-P (4) ICC/IF (7) IP (2) IHC-F (2) WB (8) FC (1)
Isotype:	IgG (6) IgG1 (2)
Conjugation:	Non-conjugated (9)
Clonality:	Monoclonal (5) Recombinant (3)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81949

	Lipoamide Dehydrogenase Antibody (YA1694) Diaphorase; Dihydrolipoamide dehydrogenase; DLDD; DLDH; GCSL; LAD; lipoamide dehydrogenase; lipoamide reductase; Lipoyl dehydrogenase; PHE3	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Lipoamide Dehydrogenase Antibody (YA1694) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lipoamide Dehydrogenase.

HY-P81949A

	Lipoamide Dehydrogenase Antibody (YA1694)(PBS only) Diaphorase; Dihydrolipoamide dehydrogenase; DLDD; DLDH; GCSL; LAD; lipoamide dehydrogenase; lipoamide reductase; Lipoyl dehydrogenase; PHE3	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Lipoamide Dehydrogenase Antibody (YA1694) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lipoamide Dehydrogenase.

HY-P85504

	Pyruvate Dehydrogenase E1 alpha Antibody (YA5196) mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase; lipoamide; alpha 1; Pyruvate dehydrogenase complex, E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 component subunit alpha; Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; somatic form.	WB, ICC/IF	Human, Mouse
	Pyruvate Dehydrogenase E1 alpha Antibody (YA5196) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Pyruvate Dehydrogenase E1 alpha.

HY-P81650

	PDK2 Antibody (YA1395) PDK2; PDHK2; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2; mitochondrial; Pyruvate dehydrogenase kinase isoform 2	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	PDK2 Antibody (YA1395) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDK2.

HY-P85321

	PDK1 Antibody (YA5013) PDK1; PDHK1; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; mitochondrial; Pyruvate dehydrogenase kinase isoform 1	WB, IP	Human, Mouse, Rat
	PDK1 Antibody (YA5013) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to PDK1.

HY-P810471

	BCKDK Antibody BCKDK, Branched Chain Keto Acid Dehydrogenase Kinase, [3-Methyl-2-Oxobutanoate Dehydrogenase [lipoamide]] Kinase, Mitochondrial, Branched-Chain Alpha-Ketoacid Dehydrogenase Kinase, BCKDH Kinase, EC 2.7.11.4, BCKDHKIN, BDK, 3-Methyl-2-Oxobutanoate Dehydrogenase [lipoamide] Kinase, Mitochondrial, Branched Chain Alpha-Ketoacid Dehydrogenase Kinase, Branched Chain Ketoacid Dehydrogenase Kinase, BCKD-Kinase, EC 2.7.11.1, EC 2.7.11, BCKDKD	WB IHC-P	Human, mouse, rat
	BCKDK Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to BCKDK.

HY-P80878

	Pyruvate Dehydrogenase E1 alpha Antibody (YA681) mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase (lipoamide) alpha 1; Pyruvate dehydrogenase complex; E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 com	WB, ICC/IF	Human, Mouse
	Pyruvate Dehydrogenase E1 alpha Antibody (YA681) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Pyruvate Dehydrogenase E1 alpha.

HY-P810637

	Phospho-PDHA1 (Ser293) Antibody (YA9899) mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase (lipoamide) alpha 1; Pyruvate dehydrogenase complex; E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 com	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	Phospho-PDHA1 (Ser293) Antibody (YA9899) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-PDHA1 (Ser293).

HY-P80878A

	Pyruvate Dehydrogenase E1 alpha Antibody (YA681)(PBS only) mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase (lipoamide) alpha 1; Pyruvate dehydrogenase complex; E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 com	WB, ICC/IF	Human, Mouse
	Pyruvate Dehydrogenase E1 alpha Antibody (YA681) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Pyruvate Dehydrogenase E1 alpha.

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lipoamide

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