14 Results for "

melanocortin receptor 4

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "melanocortin receptor 4" in MCE Product Catalog:

25
25 Publications Verification
Cat. No.: HY-P0252
CAS No.: 581-05-5
Synonyms: α-Melanocyte-Stimulating Hormone
α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) .
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25
25 Publications Verification
Cat. No.: HY-P0252A
CAS No.: 171869-93-5
Synonyms: α-Melanocyte-Stimulating Hormone TFA
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC) .
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1
1 Cited Publications
Cat. No.: HY-P0267
CAS No.: 121062-08-6
Melanotan (MT)-II is a melanocortin receptor agonist. Melanotan (MT)-II activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .
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Cat. No.: HY-P5971
CAS No.: 1456699-27-6
Synonyms: Mifomelatide
TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia. TCMCB07 has potential transport capabilities .
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Cat. No.: HY-118930A
CAS No.: 455957-71-8
Purity:  98.76%
Target:  

Melanocortin Receptor

Research Areas:  

Metabolic Disease Endocrinology

MK-0493 hydrochloride is a potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R), demonstrating significant reductions in energy intake .
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Cat. No.: HY-124740
CAS No.: 681847-92-7
Purity:  99.70%
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

ML00253764 is a selective melanocortin receptor 4 (MC4R) antagonist, can induce apoptosis by inhibiting ERK1/2 and Akt phosphorylation, and has anticancer activity .
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Cat. No.: HY-110123
CAS No.: 1706524-94-8
Purity:  99.47%
ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. ML-00253764 can cross blood-brain barrier .
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Cat. No.: HY-P5971A
Target:  

Melanocortin Receptor

Research Areas:  

Metabolic Disease

TCMCB07 TFA, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 TFA plays an important role in cachexia .
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Cat. No.: HY-P702372
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MC4R; Mutated melanocortin receptor 4; melanocortin 4 receptor; Mutant melanocortin-4 receptor; melanocortin receptor 4; BMIQ20; MC4-R
Species:  
Mouse
Source:  
E. coli Cell-free
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Cat. No.: HY-P705900
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MC4R; melanocortin receptor 4; MC4-R; BMIQ20; Mutant melanocortin-4 receptor; melanocortin 4 receptor; Mutated melanocortin receptor 4
Species:  
Human
Source:  
E. coli Cell-free
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Cat. No.: HY-P703161
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MC4R; Mutated melanocortin receptor 4; melanocortin 4 receptor; Mutant melanocortin-4 receptor; melanocortin receptor 4; BMIQ20; MC4-R
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P810898
Synonyms: melanocortin receptor 4, MC4-R, MC4R

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P0267A
CAS No.: 1036322-26-5
Melanotan (MT)-II acetate is a melanocortin receptor agonist. Melanotan (MT)-II acetate activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II acetate reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II acetate improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II acetate induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II acetate increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II acetate can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .
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Cat. No.: HY-110123R
CAS No.: 1706524-94-8
ML-00253764 hydrochloride (Standard) is the analytical standard of ML-00253764 (hydrochloride) (HY-110123). This product is intended for research and analytical applications. ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. ML-00253764 can cross blood-brain barrier .
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