35 Results for "

mouse CD3

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "mouse CD3" in MCE Product Catalog:

1
1 Cited Publications
製品番号: HY-P99124

Target:  

CD3

研究分野:  

Inflammation/Immunology

Anti-Mouse CD3 Antibody (17A2) is an anti-mouse CD3 IgG2b antibody inhibitor derived from the host Rat. Anti-Mouse CD3 Antibody (17A2) enhances T-cell proliferation and activation and stimulate IFN-γ or IL-17 production in splenic T cells. Anti-Mouse CD3 Antibody (17A2) significantly suppresses mortality in Graft-versus-host disease (GVHD) mice models .
loading...
    loading...
1
1 Cited Publications
製品番号: HY-10201S2
CAS 番号: 1210608-86-8
純度:  98.35%
別名: Bay 43-9006-13C,d3
Sorafenib- 13C,d3 (Bay 43-9006- 13C,d3) is the 13C, deuterated-labeled Sorafenib (HY-10201). Sorafenib (Bay 43-9006) is a potent oral active multikinase inhibitor. Sorafenib blocks autophosphorylation and activity of receptor tyrosine kinases (VEGFR-2, VEGFR-3) and RAF family kinases, thereby suppressing the RAF/MEK/ERK and PI3K/Akt pathways, inhibiting STAT3 phosphorylation, and selectively inhibiting the MAPK pathway in cancer cells. Sorafenib induces cell cycle arrest, autophagy, apoptosis, and PARP cleavage, reduces Bcl-2, Bcl-XL, cyclin D1 levels, and activates Bak and Bax. Sorafenib inhibits tumor growth and metastasis in mouse and rat models. Sorafenib can be used for cancer research, such as colon, breast, non-small-cell lung cancer (NSCLC), ovarian, pancreatic, melanoma, colorectal and hepatocellular carcinoma .
loading...
    loading...
1
1 Cited Publications
製品番号: HY-K0306

MCE Mouse CD3+ T Cells Negative Selection Kit is designed for the isolation of CD3+ T cells from single cell suspensions of mouse spleen cells and lymph nodes.

loading...
    loading...
製品番号: HY-P990864

Target:  

CD3

研究分野:  

Inflammation/Immunology

Anti-CD3 Antibody (OKT-3) is a kind of mouse IgG2a κ antibody inhibitor, targeting to human CD3. Anti-CD3 Antibody (OKT-3) decreases T cells. Anti-CD3 Antibody (OKT-3) can be used for the research of immunology, such as graft-versus-host disease .
loading...
    loading...
製品番号: HY-P99948
CAS 番号: 2329692-74-0
別名: AMG-596

Target:  

EGFR CD3

研究分野:  

Neurological Disease Cancer

Etevritamab (AMG-596) is a bispecific T-cell engager that targets EGFRvIII and CD3. Etevritamab simultaneously binds CD3 on T cells and EGFRvIII on glioblastoma multiforme cells, thereby forming a bridge structure. Etevritamab triggers T-cell activation, proliferation, secretion of cytotoxic substances, and tumor cell lysis. Etevritamab extends overall survival and induces tumor regression in mouse models of glioblastoma multiforme. Etevritamab can be used for research related to glioblastoma .
loading...
    loading...
製品番号: HY-P9954
CAS 番号: 509077-98-9

Target:  

CD3

研究分野:  

Cancer

Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers .
loading...
    loading...
製品番号: HY-P99623
CAS 番号: 1664355-28-5
別名: MGD006; S80880

Target:  

CD3

研究分野:  

Cancer

Flotetuzumab (MGD006; S80880) is an investigational CD123/CD3 bispecific dual-affinity retargeting antibody (DART) molecule. Flotetuzumab reactivates T cells by simultaneously binding to CD123 in target cells and CD3 in effector T cells, leading to T-cell-mediated cytotoxicity in target cells. Flotetuzumab shows inhibitory effect on a mouse model of patient-derived xenograft (PDX) in acute myeloid leukemia (AML) .
loading...
    loading...
製品番号: HY-P99152
CAS 番号: 140608-64-6
別名: Muromanab-CD3
Muromonab (Muromonab-CD3; OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients .
loading...
    loading...
製品番号: HY-P990802

Target:  

CD3

Anti-Mouse CD3ε Antibody (145-2C11) is an orally active anti-mouse CD3ε IgG1 monoclonal antibody. Anti-Mouse CD3ε Antibody (145-2C11) can improve the function of regulatory T cells (Tregs). Anti-Mouse CD3ε Antibody (145-2C11) relieves inflammatory response by inhibiting the production of pro-inflammatory cytokines and increasing the secretion of anti-inflammatory factors. Anti-Mouse CD3ε Antibody (145-2C11) can be used for researches on metabolic and immune system conditions such as diabetes and lupus. The recommend isotype control of Anti-Mouse CD3ε Antibody (145-2C11): Armenian hamster IgG, Isotype Control (HY-P990305) .
loading...
    loading...
製品番号: HY-P99916
CAS 番号: 2449199-61-3
別名: AMG-427

Target:  

FLT3 CD3 TNF Receptor

研究分野:  

Inflammation/Immunology Cancer

Emirodatamab (AMG-427) is a bispecific T-cell engager (BiTE). Emirodatamab simultaneously binds FLT3 on the surface of acute myeloid leukemia (AML) cells and CD3 on the surface of T cells, thereby precisely recruiting immune effector cells to tumor sites. Emirodatamab potently induces T cell activation, secretion of proinflammatory cytokines (such as IFNγ, TNFα), and specific cytotoxicity, effectively lysing FLT3-positive tumor cells and inhibiting their growth. Emirodatamab not only significantly prolongs survival in mouse xenograft models and eliminates diseased cells in primates, but also exhibits a synergistic enhancement effect when combined with PD-1 blockade therapy. Emirodatamab is used in studies of acute myeloid leukemia, especially relapsed or refractory cases .
loading...
    loading...
製品番号: HY-P990272

Target:  

CD3

研究分野:  

Inflammation/Immunology

Anti-Mouse CD3ε Antibody (KT3) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse CD3ε. Anti-Mouse CD3ε Antibody (KT3) increases thymocytes proliferation. Anti-Mouse CD3ε Antibody (KT3) can be used for the research of immunology .
loading...
    loading...
製品番号: HY-P990953
CAS 番号: 2640279-10-1
別名: Gen1047

Target:  

CD3

研究分野:  

Cancer

Zubotamig (Gen1047) is an CD3E/VTCN1-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Zubotamig induces T-cell mediated cytotoxicity of B7H4-positive tumor cells, triggers T-cell activation, and induces cytokine release from T cells in the presence of B7H4-expressing tumor cells. Zubotamig demonstrates antitumor activity in mouse patient-derived xenograft (PDX) models. Zubotamig can be used for the research of solid cancers (including breast, ovarian and lung cancer) .
loading...
    loading...
製品番号: HY-P99837
CAS 番号: 2367001-71-4
別名: SPV-T3a

Target:  

CD3

研究分野:  

Infection

Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .
loading...
    loading...
製品番号: HY-P991461
別名: XmAb968

Target:  

CD38

研究分野:  

Cancer

AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 & CD3E. AMG-424 kills CD38-expressing cancer cells, triggers T-cell proliferation and attenuates cytokine release. AMG 424 has antitumor activity in a bone marrow-invasive mouse cancer model and induces peripheral B-cell depletion in cynomolgus monkeys. AMG-424 can be used in multiple myeloma research. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .
loading...
    loading...
製品番号: HY-P990154
Anti-Mouse TIM-1/CD365 Antibody (3B3) is a rat-derived IgG2a κ type agonistic antibody, targeting to mouse TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3B3) enhances T-cell proliferation and responses by forming a stable TIM-1 complex and bringing TIM-1 into the T-cell receptor (TCR)-CD3 complex. Anti-Mouse TIM-1/CD365 Antibody (3B3) can be used for the researches of cancer, inflammation and immunology, such as experimental autoimmune encephalomyelitis, B16 F10 tumor and transplant .
loading...
    loading...
製品番号: HY-RS17366
研究分野:  

Others

Cd3g Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd3g gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-RS17740
研究分野:  

Others

Cd3d Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd3d gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
製品番号: HY-K0355

MCE Mouse CD3 Cell Depletion Magnetic Beads (Positive Selection) are magnetic beads covalently coupled with anti-mouse CD3 antibodies, enabling the specific binding and magnetic removal of CD3+ cells from single-cell suspensions derived from mouse spleen and other tissues. This allows efficient enrichment of the non-CD3+ cell population.

loading...
    loading...
製品番号: HY-K0354

MCE Mouse CD3/CD28 T Cell Activation Magnetic Beads are based on the two important co-stimulatory signals, without relying on feeder cells (antigen-presenting cells) or antigens, CD3 and CD28, without relying on feeder cells (antigen-presenting cells) or antigens, enabling simple and rapid T cell activation.

loading...
    loading...
製品番号: HY-P704216
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: CD3 epsilon & CD3 gamma; LCD3E & CD3G
Species:  
Source:  
loading...
    loading...