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nucleic acid intercalating agent

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Fluorescent Dyes

1

Inhibitory Antibodies

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0021
    EthD bromide
    25+ Cited Publications

    EtBr; Homidium bromide

    DNA Stain Others
    EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
    EthD bromide
  • HY-B1099
    Hycanthone
    2 Publications Verification

    DNA/RNA Synthesis Topoisomerase Parasite Infection
    Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent .
    Hycanthone
  • HY-DY1050

    DNA Stain Others
    Ethidium bromide (solution) is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
    Solvent and Concentration: Sterile water: 10 mg/Ml
    Ethidium bromide (solution)
  • HY-137265

    Flavivirus Infection
    Aminomethyltrioxsalen hydrochloride is a psoralen derivative. Aminomethyltrioxsalen hydrochloride can penetrate intact cells and react with nucleic acid secondary structures in vivo without disrupting the tissue structure of natural nucleoproteins. Aminomethyltrioxsalen hydrochloride inactivates viruses by crosslinking nucleic acid pyrimidine residues after exposure to UV-A radiation. Aminomethyltrioxsalen hydrochloride can be used in research related to dengue virus infection .
    Aminomethyltrioxsalen hydrochloride
  • HY-106991A

    S-303 dihydrochloride

    HIV Bacterial CHIKV Infection
    Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .
    Amustaline dihydrochloride
  • HY-D0021S

    EtBr-d5; Homidium-d5 bromide

    Isotope-Labeled Compounds DNA Stain Others
    EthD-d5 bromide is the deuterium labeled Ethidium bromide. EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
    EthD-d5 bromide
  • HY-16189

    NSC 264137; Celiptium

    DNA Stain Cancer
    Elliptinium acetate (NSC 264137) is a DNA intercalating agent that is highly cytotoxic to L1 210 cells and covalently binds to nucleic acids from L1210 cells. Elliptinium acetate can be used in cancer research, particularly in metastatic breast cancer .
    Elliptinium acetate
  • HY-106991AR

    S-303 dihydrochloride (Standard)

    HIV Bacterial Reference Standards CHIKV Infection
    Amustaline (dihydrochloride) (Standard) is the analytical standard of Amustaline (dihydrochloride). This product is intended for research and analytical applications. Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .
    Amustaline dihydrochloride (Standard)
  • HY-B1099R

    DNA/RNA Synthesis Topoisomerase Parasite Reference Standards Infection
    Hycanthone (Standard) is the analytical standard of Hycanthone. This product is intended for research and analytical applications. Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent .
    Hycanthone (Standard)

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