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Results for "

officinale

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Akt (3) AMPK (2) Apoptosis (3) Autophagy (3) Bacterial (3) Caspase (1) Cholinesterase (ChE) (1) COX (3) Drug Derivative (4) Drug Isomer (2) EGFR (1) Environmental Pollutants (1) ERK (1) Fungal (2) Histone Demethylase (2) HIV (2) IKK (1) Interleukin Related (6) Isotope-Labeled Compounds (2) JNK (1) MMP (3) mTOR (3) Mucin (1) NF-κB (4) NO Synthase (3) Parasite (2) PERK (1) PI3K (3) Reactive Oxygen Species (ROS) (1) Reference Standards (7) STAT (1) TGF-beta/Smad (2) TNF Receptor (1) TRP Channel (2)
By Research Areas:	Cancer (16) Cardiovascular Disease (1) Endocrinology (2) Infection (8) Inflammation/Immunology (16) Metabolic Disease (3) Neurological Disease (8)

By Targets:

5-HT Receptor (1)

Akt (3)

AMPK (2)

Apoptosis (3)

Autophagy (3)

Bacterial (3)

Caspase (1)

Cholinesterase (ChE) (1)

COX (3)

Drug Derivative (4)

Drug Isomer (2)

EGFR (1)

Environmental Pollutants (1)

ERK (1)

Fungal (2)

Histone Demethylase (2)

HIV (2)

IKK (1)

Interleukin Related (6)

Isotope-Labeled Compounds (2)

JNK (1)

MMP (3)

mTOR (3)

Mucin (1)

NF-κB (4)

NO Synthase (3)

Parasite (2)

PERK (1)

PI3K (3)

Reactive Oxygen Species (ROS) (1)

Reference Standards (7)

STAT (1)

TGF-beta/Smad (2)

TNF Receptor (1)

TRP Channel (2)

By Research Areas:

Cancer (16)

Cardiovascular Disease (1)

Endocrinology (2)

Infection (8)

Inflammation/Immunology (16)

Metabolic Disease (3)

Neurological Disease (8)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14615

[6]-Gingerol Maximum Cited Publications 13 Publications Verification (S)-(+)-[6]Gingerol	AMPK Apoptosis	Cancer
[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-14616

Shogaol 10+ Cited Publications [6]-Shogaol; 6-Shogaol	Autophagy	Cancer
Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-B0264

Guaifenesin Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate	Mucin	Neurological Disease Inflammation/Immunology
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-14621

Zingerone 5+ Cited Publications Vanillylacetone; Gingerone	Environmental Pollutants NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells . Zingerone can cross the blood-brain barrier (BBB) .

HY-N0447

8-Gingerol 5 Publications Verification	TRP Channel Bacterial Apoptosis Autophagy STAT PERK EGFR PI3K Akt mTOR Caspase MMP	Infection Cardiovascular Disease Inflammation/Immunology Cancer
8-Gingerol can be found in the rhizome of ginger (Z. officinale) and has oral bioactivity. It activates TRPV1, with an EC₅₀ value of 5.0 µM. 8-Gingerol inhibits COX-2 and also suppresses the growth of H. pylori in vitro. Additionally, 8-Gingerol exhibits anticancer, antioxidant, and anti-inflammatory properties by inhibiting the epidermal growth factor receptor (EGFR) and modulating its downstream STAT3/ERK pathway to suppress the proliferation, migration, and invasion of colorectal cancer cells. 8-Gingerol also exerts immunosuppressive effects by inhibiting oxidative stress, inducing cell cycle arrest, promoting apoptosis, and regulating autophagy. Furthermore, 8-Gingerol has cardioprotective effects. 8-Gingerol is promising for research in the fields of cancer, infection, immunosuppression, and cardiovascular diseases.

HY-N6895

Violanthin	Cholinesterase (ChE)	Inflammation/Immunology
Violanthin is isolated from the stems of Dendrobium officinale, has potent antioxidant and antibacterial activities. Violanthin inhibits acetylcholinesterase (AChE) with an IC₅₀ value of 79.80 μM .

HY-14615R

[6]-Gingerol (Standard) 1 Publications Verification (S)-(+)-[6]Gingerol (Standard)	Reference Standards AMPK Apoptosis	Cancer
-Gingerol (Standard) is the analytical standard of -Gingerol. This product is intended for research and analytical applications. -Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-N2434

[10]-Shogaol 5 Publications Verification	COX Interleukin Related NF-κB Parasite	Infection Inflammation/Immunology Cancer
[10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC₅₀ value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis .

HY-N6896

Isoviolanthin 1 Publications Verification	TGF-beta/Smad PI3K Akt mTOR MMP Histone Demethylase	Endocrinology Cancer
Isoviolanthin is a flavonoid glycoside. Isoviolanthin can be extracted from Dendrobium officinale. Isoviolanthin has a strong affinity for binding to KDM6B, CHAC2, ESCO2, and IPO4. Isoviolanthin decreases MMP-2 and MMP-9. Isoviolanthin inhibits TGF-β/Smad and PI3K/Akt/mTOR signaling pathways. Isoviolanthin increases Fhl3 expression. Isoviolanthin has cytoprotective effects. Isoviolanthin has anticancer activity against hepatocellular carcinoma .

HY-N6880A

(-)-Rabdosiin	HIV	Infection Neurological Disease
(-)-Rabdosiin is a novel phenolic marker, found from Symphytum officinale L. (-)-Rabdosiin shows antioxidant, neuroprotective or anti-HIV activities .

HY-133865

Diacetoxy-6-gingerdiol 1 Publications Verification	Interleukin Related	Metabolic Disease Inflammation/Immunology
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .

HY-W1000105

Geranial (E)-3,7-Dimethylocta-2,6-dienal	TNF Receptor Interleukin Related ERK JNK IKK COX NO Synthase Reactive Oxygen Species (ROS)	Inflammation/Immunology
Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger (Zingiber officinale). Geranial inhibits LPS-induced phosphorylation of ERK1/2, JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β, TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2. Geranial increases ROS. It can be used in the research of inflammatory diseases .

HY-14616R

Shogaol (Standard) 1 Publications Verification [6]-Shogaol (Standard); 6-Shogaol (Standard)	Reference Standards Autophagy	Cancer
Shogaol (Standard) is the analytical standard of Shogaol. This product is intended for research and analytical applications. Shogaol ( -Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-B0264R

Guaifenesin (Standard) Guaiacol glyceryl ether(Standard); Guaiphenesin(Standard); Glycerol guaiacolate (Standard)	Reference Standards Others	Neurological Disease Inflammation/Immunology
Guaifenesin (Standard) is the analytical standard of Guaifenesin. This product is intended for research and analytical applications. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-W711045

Deoxygeraniol	Drug Derivative	Others
Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings.

HY-136504

Bianthrone Dianthrone	Others	Others
Bianthrone (Dianthrone) is a natural product that can be isolated from Rheum officinale Baill. Bianthrone is a potential toxic marker of Polygonum multiflorum Thunb .

HY-N16553

(3R,5S)-[4]-Gingerdiol	Others	Inflammation/Immunology
(3R,5S)-[4]-Gingerdiol (compound 32) is a gingerdiol from Zingiber officinale. (3R,5S)-[4]-Gingerdiol can be used for anti-inflammatory research .

HY-N16519

[6]-Gingerdiol	Fungal	Infection
[6]-Gingerdiol is an antifungal agent. [6]-Gingerdiol can be isolated from Zingiber officinale. [6]-Gingerdiol shows antifungal activity against M. gypseum with a MLC value of 422 μg/mL.

HY-109088

Enexasogaol trans-6-Shogaol; (E)-[6]-Shogaol	Drug Derivative	Cancer
Enexasogaol (trans-6-Shogaol; (E)-[6]-Shogaol) is the derivative of Shogaol (HY-14616) found in Ginger (Zingiber officinale* Rosc*). Enexasogaol can be used for the research of cancer .

HY-122927

Symphytine	Others	Cancer
Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity .

HY-N1285

Senkyunolide C	Others	Others
Senkyunolide C is a natural product, that can be isolated from the rhizome of Cnidium officinale .

HY-N9092

Geranyl ferulate (E)-geranylferulic acid	NO Synthase	Infection Inflammation/Immunology
Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO) .

HY-N16501

(3S,5S)-[4]-Gingerdiol	Others	Others
(3S,5S)-[4]-Gingerdiol is a phenylalkanoid can be found in Zingiber officinale .

HY-N13114

8-Gingerdione	Others	Others
8-Gingerdione can be isolated from ginger (Zingiber officinale). 8-Gingerdione has no significant inhibitory effect on the production of inflammatory factors NO, TNF-α, and IL-6.

HY-B0264S

Guaifenesin-d3 Guaiacol glyceryl ether-d₃; Guaiphenesin-d₃; Glycerol guaiacolate-d₃	Isotope-Labeled Compounds	Neurological Disease Inflammation/Immunology
Guaifenesin-d₃ is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough .

HY-B0264S1

Guaifenesin-d5	Isotope-Labeled Compounds	Neurological Disease Inflammation/Immunology
Guaifenesin-d₅ is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Guaifenesin also has narcotic effect .

HY-N9891

12-Dehydrogingerdione 12-DHGD	NO Synthase Interleukin Related	Inflammation/Immunology
12-Dehydrogingerdione is an inhibitor of NO Synthase. 12-Dehydrogingerdione signi?cantly inhibits LPS-stimulated production of NO, IL-6 and PGE2 in Raw 264.7 cells .

HY-N0447R

8-Gingerol (Standard)	Reference Standards TRP Channel Bacterial	Infection Inflammation/Immunology Cancer
8-Gingerol (Standard) is the analytical standard of 8-Gingerol. This product is intended for research and analytical applications. 8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC₅₀ of 5.0 μM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro .

HY-14621R

Zingerone (Standard) Vanillylacetone (Standard); Gingerone (Standard)	Reference Standards NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Zingerone (Standard) is the analytical standard of Zingerone. This product is intended for research and analytical applications. Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-134635R

Dehydrozingerone (Standard)	Bacterial Fungal HIV	Infection Neurological Disease Cancer
Dehydrozingerone (Standard) is the analytical standard of Dehydrozingerone. This product is intended for research and analytical applications. Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM .

HY-N6896R

Isoviolanthin (Standard)	Reference Standards TGF-beta/Smad PI3K Akt mTOR MMP Histone Demethylase	Endocrinology Cancer
Isoviolanthin (Standard) is the analytical standard of Isoviolanthin (HY-N6896). This product is intended for research and analytical applications. Isoviolanthin is a flavonoid glycoside. Isoviolanthin can be extracted from Dendrobium officinale. Isoviolanthin has a strong affinity for binding to KDM6B, CHAC2, ESCO2, and IPO4. Isoviolanthin decreases MMP-2 and MMP-9. Isoviolanthin inhibits TGF-β/Smad and PI3K/Akt/mTOR signaling pathways. Isoviolanthin increases Fhl3 expression. Isoviolanthin has cytoprotective effects. Isoviolanthin has anticancer activity against hepatocellular carcinoma .

HY-N2434R

[10]-Shogaol (Standard)	Reference Standards COX Interleukin Related NF-κB Parasite	Infection Inflammation/Immunology Cancer
-Shogaol (Standard) is the analytical standard of -Shogaol (HY-N2434). This product is intended for research and analytical applications. [10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC₅₀ value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis .

HY-N18375

7-Gingerdiol	Drug Derivative	Others
7-Gingerdiol is a ginger phenol found in Zingiber officinale rhizomes .

HY-N10792

Methyl diacetoxy-6-gingerdiol	Others	Others
Methyl diacetoxy-6-gingerdiol is a nature product that could be isolated form the rhizomes of Zingiber officinale .

HY-N17725

(3S,5S)-5'-Methoxyoctahydrocurcumin	Others	Others
(3S,5S)-5'-Methoxyoctahydrocurcumin (Compound 13) is a diarylheptanoid that can be found in the dried rhizoma of Zingiber officinale Roscoe .

HY-N2434A

(E)-[10]-Shogaol	5-HT Receptor	Neurological Disease
(E)-[10]-Shogaol is a 5-HT_1A receptor partial agonist found in Zingiber officinale, with a K_i of 5.84 μM. (E)-[10]-Shogaol may be used in research on anxiety and depression .

HY-120912A

(E/Z)-Gingerenone A	Drug Isomer	Others
(E/Z)-Gingerenone A (Compound 42) is a diarylheptanoid compound. (E/Z)-Gingerenone A is isolated from the rhizomes of Zingiber officinale* Rosc* .

HY-N17300

Dendroside G	Drug Derivative	Others
Dendroside G is a natural product that can be found in Dendrobium officinale.

HY-N2671

5-Epilithospermoside	Others	Others
5-Epilithospermoside is a Alkaloids product that can be isolated from the roots of Lithospermum officinale. .

HY-N15733

5-Methoxy-[8]-gingerol	Others	Others
5-Methoxy-[8]-gingerol is a compound that can be isolated from ginger (Zingiber officinale) .

HY-N17465

Dendronobiloside D	Interleukin Related	Others
Dendronobiloside D is a sesquiterpene glycoside that can be isolated from Dendrobium officinale. Dendronobiloside D is an immunosuppressant that promotes the differentiation of CD4 ⁺ T cells into Treg cells .

HY-N9243

5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate	Others	Others
5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate is a Phenols product that can be isolated from the rhizomes of Zingiber officinale .

HY-100187

(Rac)-[6]-Gingerol (±)-[6]-Gingerol	Drug Isomer	Cancer
(Rac)-[6]-Gingerol is a natural product. (Rac)-[6]-Gingerol can be isolated from rhizomes of Z. officinale. (Rac)-[6]-Gingerol shows moderate anticancer activity against lung cancer, ovarian cancer, melanoma, and colon cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure