69 Results for "

olfactory

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "olfactory" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-116144
CAS No.: 119515-38-7
Purity:  98.00%
Synonyms: Lcaridin
Research Areas:  

Infection

Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial, anticandidal and antifungal properties .
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3
3 Cited Publications
Cat. No.: HY-135869
CAS No.: 1254044-38-6
Purity:  99.84%
Research Areas:  

Neurological Disease

Mito-apocynin (C11), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C11) selectively targets mitochondria, and shows neuroprotective effect. Mito-apocynin (C11) prevents hyposmia and corrects deficits in motor function .
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2
2 Cited Publications
Cat. No.: HY-135190
CAS No.: 469-61-4
Purity:  ≥98.0%
Synonyms: α-cedrene
(-)-Cedrene (α-cedrene) is a major constituent that can be found in essential oils. (-)-Cedrene (α-cedrene) is a natural, orally active ligand of mouse olfactory receptor 23, which induces skeletal muscle hypertrophy in mice. (-)-Cedrene exhibits trypanocidal (Trypanosoma b. brucei) (IC50 = 4.07 μg/mL). (-)-Cedrene is antileukemic in vitro (IC50 = 22.2 μg/mL). (-)-Cedrene has antimicrobial activity against anaerobic bacteria and yeast. (-)-Cedrene exhibits anti-obesity activity .
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2
2 Cited Publications
Cat. No.: HY-109046
CAS No.: 1038984-31-4
Purity:  99.39%
Synonyms: CX-1632; S-47445
Target:  

iGluR mTOR

Research Areas:  

Neurological Disease

Tulrampator (S-47445) is an orally active selective AMPA receptor modulator. Tulrampator possesses procognitive, enhancing synaptic plasticity, anti-depressant-anxiolytic-like, procognitive and potential neuroprotective properties. Tulrampator can be used for research of alzheimer’s disease and in major depressive disorder .
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1
1 Cited Publications
Cat. No.: HY-N2085
CAS No.: 18031-40-8
Synonyms: (S)-(-)-Perillaldehyde; (S)-Perillaldehyde
L-Perillaldehyde is a major component in the essential oil containing in Perillae Herba. Inhalation of L-Perillaldehyde shows antidepressant-like activity through the olfactory nervous function .
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1
1 Cited Publications
Cat. No.: HY-155659
Purity:  99.86%
Research Areas:  

Neurological Disease

4A7C-301 is a Nurr1 agonist with robust neuroprotective effects in vitro. 4A7C-301 significantly ameliorates neuropathological abnormalities and improves motor and olfactory dysfunctions in AAV2-mediated α-synuclein-overexpressing male mouse models. 4A7C-301 can be used for the research of Parkinson’s disease .
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1
1 Cited Publications
Cat. No.: HY-125751
CAS No.: 1434515-70-4
Purity:  99.53%
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

UCSF924, a chemical probe, is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases .
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1
1 Cited Publications
Cat. No.: HY-137016A
CAS No.: 51239-26-0
Purity:  ≥99.0%
Target:  

HCN Channel

Research Areas:  

Neurological Disease

8-Pcpt-cGMP sodium is the sodium salt form of 8-Pcpt-cGMP (HY-137016). 8-Pcpt-cGMP sodium is an agonist for cyclic nucleotide-gated (CNG) channel with an EC50 of 0.5 μM. 8-Pcpt-cGMP sodium exhibits good membrane permeability. 8-Pcpt-cGMP sodium can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction .
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-125934
CAS No.: 2464-18-8
Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite .
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Cat. No.: HY-145567
CAS No.: 23062-06-8
Purity:  99.81%
Synonyms: PH94B
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca ++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety .
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Cat. No.: HY-N8847
CAS No.: 127-41-3
Synonyms: alpha-Ionone
α-Ionone (alpha-Ionone) is an activator of the olfactory receptor OR10A6. α-Ionone induces apoptosis by activating OR10A6 and increasing the phosphorylation of the LATS-YAP-TAZ signaling axis in the Hippo pathway. α-Ionone can inhibit tumor formation both in vivo and in vitro .
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Cat. No.: HY-128900
CAS No.: 6186-98-7
Purity:  98.9%
11-cis-Vaccenyl acetate is male-specific lipid that mediates aggregation behavior in both male and female flies, which activates a few dozen olfactory neurons located in T1 sensilla on the antenna of both male and female flies .
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Cat. No.: HY-120597
CAS No.: 1256269-87-0
Purity:  99.80%
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

SAK3 is a potent T-type voltage-gated Ca 2+ channels (T-VGCCs) enhancer. SAK3 enhances Cav3.1 and Cav3.3 T-type Ca 2+ channel currents. Acute SAK3 administration improves memory deficits in olfactory-bulbectomized mice . SAK3 inhibits amyloid β plaque formation in APP-KI mice by activating the proteasome activity .
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Cat. No.: HY-125982
CAS No.: 525582-84-7
Purity:  ≥98.0%
Target:  

Insecticide

Research Areas:  

Others

VUAA1 is an insect odorant co-receptor (Orco) agonist. VUAA1 activates both heteromeric and homomeric Orco-containing channels. VUAA1 can disrupt the destructive behaviors of nuisance insects. VUAA1 can be used for insect olfactory research .
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Cat. No.: HY-139783
CAS No.: 65113-99-7
Purity:  ≥98.0%
Research Areas:  

Others

3-Campholenyl-2-butanol, a synthetic sandalwood odorant, is a selective olfactory receptor OR2AT4 agonist. 3-Campholenyl-2-butanol prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1 in the outer root sheath (ORS) .
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Cat. No.: HY-W074514
CAS No.: 3333-13-9
Target:  

Insecticide

Research Areas:  

Others

4-Allyltoluene, an aromatic compound, can elicite antennal olfactory response of Mediterranean fruit fly measured by electroantennography (EAG) .
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Cat. No.: HY-N7707
CAS No.: 28219-61-6
Research Areas:  

Cancer

Sandacanol is a specific agonist of olfactory receptor (OR10H1). Sandacanol induces cell cycle arrest and some apoptosis in bladder cancer cells .
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Cat. No.: HY-116144R
CAS No.: 119515-38-7
Synonyms: Lcaridin (Standard)
Research Areas:  

Infection

Picaridin (Standard) is the analytical standard of Picaridin. This product is intended for research and analytical applications. Picaridin (Lcaridin) is a broad spectrum arthropod repellent. The repellent and deterrent activities of Picaridin involve olfactory sensing in mosquitoes, and ticks, via their interactions with odorant receptor proteins .
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Cat. No.: HY-W753791
CAS No.: 2111-75-3
(±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM .
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