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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
oxygenase-1
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "oxygenase-1" in MCE Product Catalog:
69
69 Publications Verification
Synonyms: Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9
23
23 Cited Publications
Synonyms: Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX
Target:
Research Areas:
Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model [1].
17
12
12 Cited Publications
Target:
Research Areas:
Heme Oxygenase-1-IN-1 (Compound 2) hydrochloride is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 0.25 μM [1].
12
12 Cited Publications
Target:
Research Areas:
Heme Oxygenase-1-IN-1 (compound 2) is a potent heme oxygenase 1 (HO-1) inhibitor, with an IC50 of 0.25 μM. Heme Oxygenase-1-IN-1 can be used for cancer research [1].
4
Category:
Monophenols Simple Phenylpropanols Phenols Dicerothamnus rhinocerotis Phenylpropanoids Plants Umbelliferae
Target:
3
2
2 Cited Publications
Cat. No.: HY-B2184
CAS No.: 64506-49-6
Research Areas:
Sofalcone, a gastric antiulcer agent, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.
2
2 Cited Publications
Research Areas:
OB-24 is a selective small-molecule HO-1 inhibitor (IC50 = 1.9 μM for HO-1 and IC50 for HO-2 >100 μM). OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis [1] .
1
Category:
Flavonols Cupressaceae Flavonoids Neurological Disease Thuja occidentalisLinn. Plants Disease Research Fields Inflammation/Immunology
Target:
1
1
1 Cited Publications
Synonyms: 4-Hydroxy-3-methoxycinnamaldehyde
Category:
other families Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology
Target:
1
Cat. No.: HY-134608
CAS No.: 14325-03-2
Synonyms: Co-PPIX
Research Areas:
Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) [1].
Cat. No.: HY-W013812
CAS No.: 544-35-4
Synonyms: Linoleic Acid ethyl ester; Mandenol
Cat. No.: HY-136234
CAS No.: 13312-52-2
Synonyms: 9Z β-Carotene
Target:
Research Areas:
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. 9-cis-β-Carotene inhibits photoreceptor degeneration and restores retinal function in vivo. 9-cis-β-Carotene has the potential for the study of congenital stationary night blindness and fundus albipunctatus [1].
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Research Areas:
Keap1-Nrf2-IN-9 (Compound 11) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) inhibitor with an IC50 of 0.575 μM. Keap1-Nrf2-IN-9 increases the expression of Nrf2 target genes including heme oxygenase 1 (Hmox1), glutathione S-transferase P (GstP), and glutamate-cysteine ligase catalytic (Gclc) and modulatory (Gclm) subunits. Keap1-Nrf2-IN-9 shows no cytotoxic activity in ARPE19 cells [1].
Target:
Research Areas:
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
