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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
peptide nucleic acids
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "peptide nucleic acids" in MCE Product Catalog:
Cat. No.: HY-P0311
CAS No.: 184776-51-0
Cat. No.: HY-P4076
CAS No.: 791642-10-9
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Cat. No.: HY-P0311A
Cat. No.: HY-D0820
CAS No.: 1345823-20-2
Synonyms: Sulfo-Cyanine5-alkyne
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CY5-YNE (Sulfo-Cyanine5-alkyne) is a class of near-infrared fluorescent dye derivatives used in research related to the labeling of proteins, peptides, nucleic acids, and nanomaterials. CY5-YNE is a click chemistry reagent. It contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. CY5-YNE exhibits photostable emission properties in imaging applications, enabling covalent labeling of azide-modified substrates .
Cat. No.: HY-P3150
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Recombinant Proteinase K is a serine protease that cleaves the carboxy-terminated peptide bonds of aliphatic and aromatic amino acids. Recombinant Proteinase K can be used to digest proteins and remove contamination from nucleic acid preparations .
Cat. No.: HY-P4084A
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Cat. No.: HY-D2891
CAS No.: 2071694-39-6
Cat. No.: HY-151738
CAS No.: 1935981-35-3
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Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W540122
CAS No.: 186046-81-1
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Fmoc-PNA-C (Bhoc)-OH is a cytosine peptide nucleic acid (PNA) monomer protected by Fmoc/Bhoc. Fmoc-PNA-C (Bhoc)-OH can be used for solid-phase synthesis of long-chain PNAs, including the 20-mer PNA targeting Nnmt mRNA and the PNA targeting the tyrosinease gene to inhibit melanogenesis. Fmoc-PNA-C (Bhoc)-OH can be applied in studies related to type 2 diabetes and Escherichia coli infections .
Cat. No.: HY-151778
CAS No.: 2250433-81-7
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Fmoc-Abg(N3)-OH is a click chemistry reagent containing an azide group. Fmoc-Abg(N3)-OH has the potential to synthesize peptide nucleic acids (PNA) and peptoids. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-W320685
CAS No.: 147325-09-5
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(S)-N-Boc-L-homoserine ethyl ester is a synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine.
Cat. No.: HY-W012443
CAS No.: 2039-96-5
Cat. No.: HY-P1566
CAS No.: 395069-92-8
Cat. No.: HY-155995
CAS No.: 2762209-68-5
Synonyms: MK-905
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Pro-905 is a phosphite peptide with antitumor activity. Pro-905 delivers the active nucleotide antimetabolite thioguanosine monophosphate (TGMP) to the tumor. Pro-905 effectively prevents incorporation of purine salvage substrates into nucleic acids and inhibits colony formation in human malignant peripheral nerve sheath tumors (MPNST) cells. Pro-905 inhibits purine salvage incorporation to nucleic acids and prevents cell growth. Pro-905 inhibits the growth of MPNST and enhances the anti-tumor efficacy of JHU395 (HY-124778) .
Cat. No.: HY-174289
CAS No.: 2408481-83-2
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TMTHSI succinimide NHS ester is a highly efficient cyclic alkyne click reagent. TMTHSI succinimide NHS ester has the primary activity to rapidly undergo strain-promoted cycloaddition reactions with azides. TMTHSI succinimide NHS ester is easily functionalized and can be linked to a variety of small molecules and (peptides, nucleic acids) biologics via a variety of linkers .
Cat. No.: HY-W025936
CAS No.: 186046-83-3
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Cat. No.: HY-D2758
CAS No.: 1911598-65-6
Synonyms: Etienic acid; Testosterone-17β-carboxylic acid; 3-Oxoandrost-4-ene-17β-carboxylic acid
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Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research .
Cat. No.: HY-D0820A
Synonyms: Sulfo-Cyanine5-alkyne triethylamine
Research Areas:
CY5-YNE triethylamine (Sulfo-Cyanine5-alkyne triethylamine) is a class of near-infrared fluorescent dye derivatives used in research related to the labeling of proteins, peptides, nucleic acids, and nanomaterials. CY5-YNE triethylamine is a click chemistry reagent. It contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. CY5-YNE triethylamine exhibits photostable emission properties in imaging applications, enabling covalent labeling of azide-modified substrates .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
