136 Results for "

phenolic antioxidant

" in MedChemExpress (MCE) Product Catalog:
Products (136)

136 Results for "phenolic antioxidant" in MCE Product Catalog:

138
Curcumin
Curcumin
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138 Publications Verification
Cat. No.: HY-N0005
CAS No.: 458-37-7
Synonyms: Diferuloylmethane; Natural Yellow 3; Turmeric yellow
Category:  

Anti-aging Plants Food Research Sunscreen Pigments Phenols Polyphenols Cosmetic Research Curcuma longa Disease Research Fields Cancer Zingiberaceae

Target:  

Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis Apoptosis

Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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38
Chlorogenic acid
Chlorogenic acid
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38 Cited Publications
Cat. No.: HY-N0055
CAS No.: 327-97-9
Synonyms: 3-O-Caffeoylquinic acid; Heriguard; NSC-407296
Category:  

Caprifoliaceae Anti-aging Lonicera japonica Thunb. Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Microorganisms Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Disease Research Fields Inflammation/Immunology Cancer

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite

Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .
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16
Isochlorogenic acid A
Isochlorogenic acid A
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16 Cited Publications
Cat. No.: HY-N0056
CAS No.: 2450-53-5
Synonyms: 3,5-Dicaffeoylquinic acid; 3,5-CQA
Category:  

Caprifoliaceae Lonicera japonica Thunb. Ketones, Aldehydes, Acids Phenols Polyphenols Plants Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Free Radical Scavengers Reactive Oxygen Species (ROS) HBV Endogenous Metabolite HIV Bacterial

Isochlorogenic acid A (3,5-Dicaffeoylquinic acid) is a natural phenolic acid with anti-mutagenicity, anti-HBV, anti-HIV, anti-oxidant, anti-bacterial, and anti-inflammatoryy activities .
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11
Carvacrol
Carvacrol
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11 Cited Publications
Cat. No.: HY-N0711
CAS No.: 499-75-2
Synonyms: Cymophenol
Category:  

Preservatives Monophenols Labiatae Phenols Plants Derris elliptica (Roxb.) Benth. Disease Research Fields Inflammation/Immunology Food Research

Target:  

Environmental Pollutants Apoptosis Endogenous Metabolite Notch Fungal Bacterial

Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .
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9
Danshensu
Danshensu
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9 Cited Publications
Cat. No.: HY-N1913
CAS No.: 76822-21-4
Synonyms: Dan shen suan A; Salvianic acid A
Category:  

Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis

Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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9
Danshensu sodium
Danshensu sodium
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9 Cited Publications
Cat. No.: HY-N1913A
CAS No.: 81075-52-7
Synonyms: Dan shen suan A sodium; Salvianic acid A sodium
Category:  

Simple Phenylpropanols Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Phenylpropanoids Plants

Target:  

Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis

Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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7
Olive oil
Olive oil
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7 Cited Publications
Cat. No.: HY-108749
CAS No.: 8001-25-0
Synonyms: Cropure OL
Olive oil (Cropure OL) is an oleaginous compound found in the fruit of the Olea europaea tree . Olive oil contains many phenolic components and exerts antioxidant activity. Olive oil exhibits hydroxyl radical scavenging, platelet aggregation inhibition and xanthine oxidase inhibitory activity. Olive oil can promote wound healing and relieve inflammation. Olive oil can be used for the research of inflammation, cancer, metabolic and cardiovascular disease, such as diabetic foot ulcers and inflammatory bowel disease .
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6
Cryptochlorogenic acid
Cryptochlorogenic acid
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6 Cited Publications
Cat. No.: HY-N0787
CAS No.: 905-99-7
Synonyms: 4-Caffeoylquinic acid; 4-O-Caffeoylquinic acid
Category:  

Plants Moraceae Endogenous metabolite Simple Phenylpropanols Other Diseases Phenols Polyphenols Phenylpropanoids Disease Research Fields Morus alba Linn.

Target:  

Endogenous Metabolite NF-κB Keap1-Nrf2 mTOR HIF/HIF Prolyl-Hydroxylase

Cryptochlorogenic acid (4-Caffeoylquinic acid) is a naturally occurring phenolic acid compound with oral effectiveness, anti-inflammatory, antioxidant and anti-cardiac hypertrophy effects. Alleviating LPS (HY-D1056) and ISO (HY-B0468) by regulating proinflammatory factor expression, inhibiting NF-κB activity, promoting Nrf2 nuclear transfer, and regulating PI3Kα/Akt/ mTOR / HIF-1α signaling pathway Induced physiological stress response .
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5
Thymol
Thymol
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5 Cited Publications
Cat. No.: HY-N6810
CAS No.: 89-83-8
Category:  

Infection Monophenols Labiatae Phenols Plants Derris elliptica (Roxb.) Benth. Disease Research Fields Inflammation/Immunology Cancer

Target:  

Apoptosis Bacterial Fungal

Thymol is a TRPA1 agonist. Thymol induces cancer cell apoptosis. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects .
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5
Methyl gallate
Methyl gallate
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5 Cited Publications
Cat. No.: HY-N2010
CAS No.: 99-24-1
Synonyms: Gallincin; NSC 363001
Category:  

Cardiovascular Disease Infection Paeonia lactiflora Pall. Phenols Polyphenols Plants Paeoniaceae Disease Research Fields

Target:  

Bacterial HIV Reactive Oxygen Species (ROS)

Methyl gallate is a plant phenolic with antioxidant, anticancer, and anti-inflammatory activities. Methyl gallate also shows bacterial inhibition activity. Methyl gallate also has anti-HIV-1 and HIV-1 enzyme inhibitory activities.
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5
Sinapinic acid
Sinapinic acid
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5 Cited Publications
Cat. No.: HY-W009732
CAS No.: 530-59-6
Synonyms: Sinapic acid
Category:  

other families Monophenols Simple Phenylpropanols Metabolic Disease Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

HDAC Angiotensin-converting Enzyme (ACE) Reactive Oxygen Species (ROS) Apoptosis

Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM , and also inhibits ACE-I activity . Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells . Sinapinic acid shows antioxidant and antidiabetic activities . Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats .
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4
Purpurogallin
Purpurogallin
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4 Cited Publications
Cat. No.: HY-12136
CAS No.: 569-77-7
Purity:  96.87%
Category:  

Phenols Polyphenols Plants Fagaceae Disease Research Fields Inflammation/Immunology Macaranga denticulata (Blume) Müll. Arg. Cancer

Target:  

Xanthine Oxidase

Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects .
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3
Curcumin (Standard)
Curcumin (Standard)
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3 Cited Publications
Cat. No.: HY-N0005R
CAS No.: 458-37-7
Synonyms: Diferuloylmethane (Standard); Natural Yellow 3 (Standard); Turmeric yellow (Standard)
Category:  

Microorganisms Phenols Polyphenols Plants Curcuma longa Zingiberaceae

Target:  

Reference Standards Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis

Curcumin (Standard) is the analytical standard of Curcumin (HY-N0005). This product is intended for research and analytical applications. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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2
Noreugenin
Noreugenin
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2 Cited Publications
Cat. No.: HY-N3029
CAS No.: 1013-69-0
Category:  

Natural Products  Rhododendron dauricum Linn. Plants Aloe arborescens Liliaceae Other Diseases Phenols Polyphenols Ericaceae Disease Research Fields

Target:  

Interleukin Related Apoptosis Glutathione Peroxidase SOD Glutathione S-transferase Necroptosis

Noreugenin is a phenolic compound found in Calea uniflora Less. Noreugenin inhibits myeloperoxidase activity and reduces levels of proinflammatory cytokines IL-1β and IL-17A levels in LPS (HY-D1056)-induced murine pleurisy model. Noreugenin reduces apoptosis and necrosis. Noreugenin reduces lipid peroxidation, and antioxidant enzyme (CAT, SOD, GST) activity. Noreugenin exhibits anti-inflammatory and antioxidant effects. Noreugenin can be used for the research of inflammatory conditions, such as pleurisy .
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2
2-Hydroxycinnamic acid
2-Hydroxycinnamic acid
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2 Cited Publications
Cat. No.: HY-W012531
CAS No.: 614-60-8
Category:  

Infection Cinnamomum cassia (L.) D. Don Monophenols Simple Phenylpropanols Phenols Phenylpropanoids Plants Lauraceae Disease Research Fields

Target:  

HIV SARS-CoV Endogenous Metabolite Bacterial

2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .
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2
Tea polyphenol
Tea polyphenol
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2 Cited Publications
Cat. No.: HY-N1925
CAS No.: 84650-60-2
Category:  

Phenols Plants Camellia sinensis (L.) O. Ktze. Research on Agricultural Breeding Disease Research Fields Inflammation/Immunology Cancer Theaceae Agricultural Research

Target:  

Apoptosis Autophagy

Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen metabolism .
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2
Chebulic acid
Chebulic acid
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2 Cited Publications
Cat. No.: HY-N4170
CAS No.: 23725-05-5
Category:  

Combretaceae Ketones, Aldehydes, Acids Metabolic Disease Phenols Polyphenols Terminalia chebula Retz. Plants Disease Research Fields

Target:  

Keap1-Nrf2 Reactive Oxygen Species (ROS)

Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .
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2
HTHQ
HTHQ
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2 Cited Publications
Cat. No.: HY-100768
CAS No.: 148081-72-5
Purity:  99.89%
Synonyms: 1-O-hexyl-2,3,5-trimethylhydroquinone; HX-1171; BTT-105
Target:  

Reactive Oxygen Species (ROS)

Research Areas:  

Cancer

HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals .
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1
4-Hydroxybenzyl alcohol
4-Hydroxybenzyl alcohol
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1 Cited Publications
Cat. No.: HY-Y0892
CAS No.: 623-05-2
Category:  

Neurological Disease Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Monophenols Gastrodia elata Bl. Orchidaceae Phenols Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Endogenous Metabolite

4-Hydroxybenzyl alcohol is a phenolic compound widely distributed in various kinds of plants. Anti-inflammatory, anti-oxidant, anti-nociceptive activity. Neuroprotective effect. Inhibitor of tumor angiogenesis and growth .
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1
Succinobucol
Succinobucol
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1 Cited Publications
Cat. No.: HY-14937
CAS No.: 216167-82-7
Purity:  99.62%
Synonyms: AGI-1067; Probucol monosuccinate
Target:  

Reactive Oxygen Species (ROS)

Research Areas:  

Cardiovascular Disease Inflammation/Immunology Cancer

Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects.
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