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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
poorly
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "poorly" in MCE Product Catalog:
166
166 Publications Verification
Cat. No.: HY-17031
CAS No.: 182410-00-0
Synonyms: Sulfobutylether-β-Cyclodextrin
15
15 Cited Publications
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BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM .
1
1 Cited Publications
Cat. No.: HY-Y1892
CAS No.: 121548-04-7
1
1 Cited Publications
Cat. No.: HY-140741
Purity: 99.89%
1
1 Cited Publications
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LP-922761 is a potent, selective and orally active adapter protein-2 associated kinase 1 (AAK1) inhibitor with IC50s of 4.8 nM and 7.6 nM in enzyme and cell assays, respectively. LP-922761 also inhibits BMP-2-inducible protein kinase (BIKE) with an IC50 of 24 nM. LP-922761 exhibits no significant activity at cyclin G-associated kinase (GAK), opioid, adrenergic α2 or GABAa receptors .
Synonyms: 2,6-Di-O-methyl-β-cyclodextrin
Cat. No.: HY-401424
CAS No.: 61791-12-6
Synonyms: Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
Cat. No.: HY-W250168
CAS No.: 9004-98-2
Synonyms: Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10
Cat. No.: HY-W040040
CAS No.: 17465-86-0
Cat. No.: HY-155882
CAS No.: 80506-64-5
Synonyms: mPEG750-NH2
Research Areas:
Soya Lecithin is a phospholipid mixture that can be used as a drug delivery vehicle and is a pharmaceutical excipient. Soya Lecithin can form a lipid bilayer structure through self-assembly, and its binding properties are amphiphilic (hydrophilic head and hydrophobic tail), encapsulating hydrophobic drugs. Soya Lecithin forms stable nanoliposomes or microemulsions, improves the solubility and cellular uptake efficiency of poorly soluble drugs (such as Curcumin (HY-N0005)), and exerts activities such as enhancing drug delivery and regulating cell proliferation .
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SBE13 Hydrochloride is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; SBE13 Hydrochloride poorly inhibits Plk2 (IC50>66 μM) or Plk3 (IC50=875 nM).
Cat. No.: HY-P4279
CAS No.: 1370698-94-4
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IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively.
STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly .
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NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly .
Cat. No.: HY-P5492
CAS No.: 74838-20-3
Synonyms: Delta-lysin
Cat. No.: HY-167028
CAS No.: 2421228-20-6
Cat. No.: HY-W440894
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
