20 Results for "

porcine lipase

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "porcine lipase" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N8599
CAS No.: 531-58-8
Cichoriin is an orally active coumarin glycoside with broad biological activities. Cichoriin exhibits inhibitory activities against α-amylase, α-glucosidase, pancreatic lipase and DPP-IV, with IC50 values of 5.76, 2.94, 16.83 and 9.16 μg/mL, respectively. Cichoriin significantly improves metabolic dysfunction-associated steatohepatitis (MASH) in mice by activating the AMPK signaling pathway. Cichoriin upregulates PPAR-γ in adipose tissue and alleviates obesity and associated cardiorenal injury in rats. Cichoriin blocks monosodium urate crystal-induced activation of the NLRP3 inflammasome and cell pyroptosis by inhibiting P2Y14R (IC50 = 8.47 nM). In silico virtual screening reveals that Cichoriin has a strong binding affinity for SARS-CoV-2 .
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Cat. No.: HY-W013168
CAS No.: 1492-30-4
Synonyms: 4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate; pNpp
Target:  

Lipase

Research Areas:  

Others

4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate) is a chromogenic substrate for lipases and esterases. Upon enzymatic hydrolysis, 4-Nitrophenyl palmitate releases p-nitrophenol, which can be quantified by colorimetric detection at 410 nm as a measure of enzymatic activity. 4-Nitrophenyl palmitate is used to characterize the activity of various bacterial and mammalian enzymes, including those from Burkholderia and porcine pancreatic lipase .
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Cat. No.: HY-126411
CAS No.: 28148-89-2
Purity:  96.75%
Peonidin-3-O-galactoside chloride is an anthocyanin with antioxidant properties and blood-brain barrier permeability. Peonidin-3-O-galactoside chloride inhibits pancreatic lipase, with an IC50 value of 23.2 μg/mL against porcine pancreatic lipase. Peonidin-3-O-galactoside chloride mediates neuroprotection, regulates glucose metabolism, protects cells from high glucose-induced damage, promotes glucose uptake and increases ATP production. Peonidin-3-O-galactoside (chloride) can be used in the research of obesity and neurodegenerative diseases .
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Cat. No.: HY-P2879A
CAS No.: 9026-00-0
Research Areas:  

Metabolic Disease

Cholesterol esterase, Porcine pancreas is an enzyme that hydrolyzes cholesteryl esters into cholesterol and free fatty acids in the intestine. Cholesterol esterase, also known as bile salt-stimulated lipase or carboxyl ester lipase, functions to promote cholesterol absorption .
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Cat. No.: HY-77817
CAS No.: 1003-29-8
Synonyms: 2-Formylpyrrole
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) is a heterocyclic organic compound that serves as a scaffold for the synthesis of various bioactive compounds .
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Cat. No.: HY-119741
CAS No.: 200399-47-9
Salacinol, compound found in Salacia reticulata, is an orally active α-glucosidase/lipase inhibitor. Salacinol inhibits enzymatic activity of intestinal maltase (IC50 = 3.2 μg/mL, Ki = 0.31 μg/mL), sucrase (IC50 = 0.84 μg/mL, Ki = 0.32 μg/mL), and isomaltase (IC50 = 0.59 μg/mL, Ki = 0.47 μg/mL), and inhibits increases in serum glucose levels in sucrose-loaded rats. Salacinol also inhibits pancreatic lipase and lipoprotein lipase. Salacinol can be used for the research of diabetes mellitus .
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Cat. No.: HY-W127391
CAS No.: 17598-94-6
Synonyms: (Rac)-1,2-Didodecanoylglycerol
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
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Cat. No.: HY-Y0606
CAS No.: 3144-16-9
Synonyms: (+)-10-Camphorsulfonic acid
Target:  

Lipase

Research Areas:  

Metabolic Disease

(+)-Camphor-10-sulfonic acid ((+)-10-Camphorsulfonic acid) is a ligand of pancreatic lipase, with an IC50 of 24.8 μM against porcine pancreatic lipase. As an antagonist, (+)-Camphor-10-sulfonic acid prevents Orlistat (HY-B0218) from binding to the active site of pancreatic lipase. (+)-Camphor-10-sulfonic acid can be used in research related to obesity .
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Cat. No.: HY-N7163
CAS No.: 160436-10-2
Synonyms: (2S)-3',5,5'7-Tetrahydroxyflavanone
(2S)-5,7,3',5'-Tetrahydroxyflavanone ((2S)-3',5,5'7-Tetrahydroxyflavanone) is a porcine pancreatic lipase modulator with an IC50 of >200 μM against porcine pancreatic lipase. (2S)-5,7,3',5'-Tetrahydroxyflavanone interacts with an enzyme involved in triglyceride hydrolysis .
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Cat. No.: HY-N10606
Uvagrandol potently inhibits α-glucosidase and porcine lipase (IC50: 15.2 μM, 11.2 μM respectively). Uvagrandol can be used in the research of Type 2 diabetes and obesity .
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Cat. No.: HY-Y1422T
Target:  

Lipase

Research Areas:  

Metabolic Disease

Lipase, Porcine is an orally active triglyceride hydrolase and fat absorption enhancer. Lipase, Porcine catalyzes the breakdown of triglycerides into fatty acids, as well as the hydrolysis of triglycerides and other carboxylic acid esters. Lipase, Porcine increases the absorption coefficients of fats, proteins and carbohydrates. Lipase, Porcine can be used in studies related to exocrine pancreatic insufficiency and congenital pancreatic triglyceride lipase deficiency .
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Cat. No.: HY-N8362
CAS No.: 19275-44-6
1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity .
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Cat. No.: HY-N17567
CAS No.: 1941207-42-6
Morusalnol A is a arylbenzofuran derivative found in the root bark of Morus alba. Morusalnol A is a pancreatic lipase inhibitor with a porcine pancreatic lipase IC50 of 0.71 μM. Morusalnol A inhibits pancreatic lipase activity. Morusalnol A can be used for the research of obesity .
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Cat. No.: HY-77817R
CAS No.: 1003-29-8
Synonyms: 2-Formylpyrrole (Standard)
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) Standard is the analytical standard of Pyrrole-2-carboxaldehyde (HY-77817). This product is intended for research and analytical applications. Pyrrole-2-carboxaldehyde is a heterocyclic organic compound that serves as a scaffold for the synthesis of various bioactive compounds .
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Cat. No.: HY-N17876
CAS No.: 350590-46-4
Royleanonic acid is an abietan-type diterpene found in the leaves of Salvia officinalis L. Royleanonic acid is a porcine pancreatic lipase inhibitor with an IC50 of 35 μg/mL .
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Cat. No.: HY-N21863
CAS No.: 105591-35-3
Isochiisanoside is a lupane-type triterpenoid triglycoside found in the leaves of Acanthopanax sessiliflorus. Isochiisanoside dose-dependently inhibits LPS (HY-D1056A1))-induced NO (IC50 = 64.25 μM) and PGE2 production in macrophages without obvious cytotoxicity. Isochiisanoside shows weak inhibitory activity against porcine pancreatic lipase. Isochiisanoside can be used in inflammation-related research .
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Cat. No.: HY-N11721
CAS No.: 138373-23-6
5-Hydroxyaloin A is a polyphenolic antioxidant agent. 5-Hydroxyaloin A forms hydrogen bonding interactions at lipase’s active site and SOD’s active site with low binding energy. 5-Hydroxyaloin A inhibits microsomal lipid peroxidation induced by ferrous-cysteine, reducing malondialdehyde production. 5-Hydroxyaloin A can be used for the research of obesity .
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Cat. No.: HY-N19783
CAS No.: 2245106-27-6
Carambolaside M acts as an ABTS radical cation scavenger. Carambolaside M scavenges ABTS radical cations. Carambolaside M is isolated from the fresh sweet fruits of Averrhoa carambola L., a plant belonging to the genus Averrhoa in the Oxalidaceae family .
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Cat. No.: HY-N19100A
CAS No.: 93158-43-1
Target:  

Others

Research Areas:  

Others

7-Hexadecenedioic acid is an asymmetric olefinic aliphatic α,ω-dicarboxylic acid. When 7-Hexadecenedioic acid undergoes esterification with n-butanol under catalysis by PPL, it produces a 1:1 mixture of its two monobutyl ester isomers .
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Cat. No.: HY-W719455
CAS No.: 55483-00-6
Pungenin is a compound that can be isolated from Leontopodium leontopodioides. Pungenin exhibits lipase inhibitory activity. Pungenin reuduces triglyceride absorption .
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