19 Results for "

pp60

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "pp60" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P701321
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src (p60-Src); SRC1
Species:  
Source:  
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Cat. No.: HY-P1199
CAS No.: 149299-77-4
Target:  

Peptides

Research Areas:  

Others

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527 .
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Cat. No.: HY-P1189
CAS No.: 154303-05-6
Echistatin is a naturally derived RGD-containing snake venom peptide. Echistatin exhibits an IC50 of 0.6 nM against mouse αvβ3 integrin, and acts as an antagonist against αvβ3, αII3, α5β1 integrins, pp125 FAK and paxillin. Echistatin reduces the phosphorylation of pp125 FAK and paxillin, inhibits the autophosphorylation and kinase activity of pp125 FAK, and weakens its binding to pp60src and paxillin. Echistatin disrupts the actin cytoskeleton and focal adhesions, induces melanoma cell detachment from fibronectin, and regulates cell adhesion and motility. Echistatin inhibits osteoclast maturation and migration, bone resorption, platelet aggregation, bone loss, as well as adhesion and metastasis of Lewis lung cancer cells; it also increases the number of osteoclasts and bone coverage area in mice with secondary hyperparathyroidism. Echistatin can be used in research related to melanoma, lung cancer and secondary hyperparathyroidism .
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Cat. No.: HY-P2548
CAS No.: 176042-83-4
Target:  

EGFR

Research Areas:  

Others

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .
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Cat. No.: HY-W013857
CAS No.: 125697-93-0
Target:  

CaMK EGFR Src

Research Areas:  

Cancer

Lavendustin C is a potent Ca 2+ calmodulin-dependent kinase II (CaMK II) inhibitor with an IC50 of 0.2 μM. Lavendustin C inhibits EGFR-associated tyrosine kinase (IC50=0.012 μM) and pp60 c-src(+) kinase (IC50=0.5 μM) .
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Cat. No.: HY-P1189A
Echistatin TFA is a naturally derived RGD-containing snake venom peptide. Echistatin TFA exhibits an IC50 of 0.6 nM against mouse αvβ3 integrin, and acts as an antagonist against αvβ3, αII3, α5β1 integrins, pp125 FAK and paxillin. Echistatin TFA reduces the phosphorylation of pp125 FAK and paxillin, inhibits the autophosphorylation and kinase activity of pp125 FAK, and weakens its binding to pp60src and paxillin. Echistatin TFA disrupts the actin cytoskeleton and focal adhesions, induces melanoma cell detachment from fibronectin, and regulates cell adhesion and motility. Echistatin TFA inhibits osteoclast maturation and migration, bone resorption, platelet aggregation, bone loss, as well as adhesion and metastasis of Lewis lung cancer cells; it also increases the number of osteoclasts and bone coverage area in mice with secondary hyperparathyroidism. Echistatin TFA can be used in research related to melanoma, lung cancer and secondary hyperparathyroidism .
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Cat. No.: HY-N7160
CAS No.: 17241-40-6
2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells .
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Cat. No.: HY-P11624
Target:  

Apoptosis

Research Areas:  

Cancer

PP-60 is an apoptosis inducer. PP-60 inhibits the proliferation of cancer cells and induces cancer cell apoptosis. PP-60 exerts anti-tumor effects in nude mouse liver tumor models. PP-60 is applicable to research related to cancers such as liver cancer, lung cancer, and prostate cancer .
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Cat. No.: HY-P3773
CAS No.: 168781-78-0
Target:  

Src

Research Areas:  

Cancer

p60c-src substrate II is an efficient pentapeptide substrate for the tyrosine kinase pp60c-src .
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Cat. No.: HY-108487
CAS No.: 190078-50-3
Synonyms: Ac-Tyr-Glu-N(n-C5H11)2
Target:  

Src

Research Areas:  

Cancer

N-Acetyl-O-phosphono-Tyr-Glu dipentylamide (Ac-Tyr-Glu-N(n-C5H11)2), a dipeptide, is a pp60 c-src SH2 domain inhibitor. N-Acetyl-O-phosphono-Tyr-Glu dipentylamide can be used for cancer research .
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Cat. No.: HY-P3744
CAS No.: 81493-98-3
Target:  

EGFR

Research Areas:  

Others

pp60v-src Autophosphorylation site is a synthetic peptide. pp60v-src Autophosphorylation site can be used for various biochemical studies .
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Cat. No.: HY-131721
CAS No.: 218461-97-3
Target:  

Drug Derivative Mitosis

Research Areas:  

Others

14,15-EET-SI is a sulfonimide (SI) analog metabolized from 14,15-EET, which is also an effective mitogen. 14,15-EET-SI can stimulate the incorporation of [3H] thymidine, activate pp60c-src and initiate the tyrosine kinase cascade, mediating their mitotic effects. Additionally, 14,15-EET-SI can increase cell proliferation as well as the expression of c-fos and egr-1 mRNA .
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Cat. No.: HY-P86318
Synonyms: Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P705885
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src (p60-Src); SRC1
Species:  
Source:  
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Cat. No.: HY-P706166
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src (p60-Src); SRC1
Species:  
Source:  
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Cat. No.: HY-P82911
Synonyms: SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Rat

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Cat. No.: HY-P86105
Synonyms: SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src; ASV;

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P82911A
Synonyms: SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Rat

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Cat. No.: HY-P705884
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src (p60-Src); SRC1
Species:  
Source:  
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